Abstract:
:High mobility group box 1 (HMGB1) is a pro-inflammatory cytokine that emerges as a promising peripheral marker of inflammation. HMGB1 and C-reactive protein levels were assessed in plasma of control subjects and remitted patients with bipolar disorder (BD). HMGB1 levels were significantly higher in patients with BD as compared to control subjects whereas C-reactive protein levels did not differ between the two groups. No significant effect of potential covariates was identified. The results of this pilot study suggest that HMGB1 might be a specific peripheral marker of inflammation in BD.
journal_name
J Neuroimmunoljournal_title
Journal of neuroimmunologyauthors
Marie-Claire C,Courtin C,Curis E,Bouaziz-Amar E,Laplanche JL,Jacob A,Etain B,Blanchard A,Bellivier Fdoi
10.1016/j.jneuroim.2019.576993subject
Has Abstractpub_date
2019-09-15 00:00:00pages
576993eissn
0165-5728issn
1872-8421pii
S0165-5728(19)30128-6journal_volume
334pub_type
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