Abstract:
:Activating mutations of FLT3 occur in about 30% of acute myeloid leukemia (AML) cases and are associated with relapse and poor prognosis. Midostaurin is the first drug approved for AML since 2000, and the first multi-kinase inhibitor approved for the FLT3-mutant subtype. To view this Bench to Bedside, open or download the PDF.
journal_name
Celljournal_title
Cellauthors
Rasko JEJ,Hughes TPdoi
10.1016/j.cell.2017.11.007subject
Has Abstractpub_date
2017-11-16 00:00:00pages
981issue
5eissn
0092-8674issn
1097-4172pii
S0092-8674(17)31316-8journal_volume
171pub_type
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