Abstract:
:During RNA interference (RNAi), Dicer generates short interfering RNAs (siRNAs), which then guide target mRNA cleavage by the RISC complex. Now, Liu et al. identify R2D2, a Dicer-associated protein that is important for siRNA incorporation into RISC, thus linking the initiation and execution phases of RNAi.
journal_name
Celljournal_title
Cellauthors
Pellino JL,Sontheimer EJdoi
10.1016/s0092-8674(03)00806-7subject
Has Abstractpub_date
2003-10-17 00:00:00pages
132-3issue
2eissn
0092-8674issn
1097-4172pii
S0092867403008067journal_volume
115pub_type
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