Abstract:
:The posttranslational modification of proteins by methylglyoxal, a highly reactive compound derived from glycolysis, may contribute to aging, diabetes, and other disorders. In this issue of Cell, Brownlee and colleagues (Yao et al., 2006) demonstrate a specific mechanism by which methylglyoxal modifies a transcriptional corepressor to enhance gene expression.
journal_name
Celljournal_title
Cellauthors
Ramasamy R,Yan SF,Schmidt AMdoi
10.1016/j.cell.2006.01.002subject
Has Abstractpub_date
2006-01-27 00:00:00pages
258-60issue
2eissn
0092-8674issn
1097-4172pii
S0092-8674(06)00050-Xjournal_volume
124pub_type
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