It takes a PHD to read the histone code.

Abstract:

:The pattern of histone modifications, called the histone code, influences transitions between chromatin states and the regulation of transcriptional activity. Four recent papers describe how plant homeodomain (PHD) finger proteins read part of this code. The PHD finger may promote both gene expression and repression through interactions with trimethylated lysine 4 on histone 3 (H3K4), a universal modification at the beginning of active genes.

journal_name

Cell

journal_title

Cell

authors

Mellor J

doi

10.1016/j.cell.2006.06.028

subject

Has Abstract

pub_date

2006-07-14 00:00:00

pages

22-4

issue

1

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(06)00821-X

journal_volume

126

pub_type

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