Abstract：
:In embryos of X. laevis, and many other species, early development requires targeted movements of molecules and molecular aggregates within the oocyte or egg cytoplasm. One well-known example in Xenopus is the aggregation of germ plasm, a group of cytoplasmic islands that become distributed during the first few cell cycles to cells that will give rise to the germ line. Nothing is known about the cytoskeletal motor proteins that may drive these movements. We show here that a recently identified Xenopus kinesin-like protein, Xklp1, is required for the aggregation of germ plasm in early Xenopus embryos, thus assigning this protein a role in a developmentally important cytoplasmic localization.
journal_name
Celljournal_title
Cellauthors
Robb DL,Heasman J,Raats J,Wylie Cdoi
10.1016/s0092-8674(00)81990-xsubject
Has Abstractpub_date
1996-11-29 00:00:00pages
823-31issue
5eissn
0092-8674issn
1097-4172pii
S0092-8674(00)81990-Xjournal_volume
87pub_type
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