Abstract:
:The role of the noncoding genome in cancer biology is continually expanding. Cho et al. reveal a new and unexpected mechanism for the regulation of MYC expression mediated by the promoter sequence of its neighbor gene PVT1. This DNA element acts as a promoter-enhancer competitor and a candidate tumor suppressor.
journal_name
Celljournal_title
Cellauthors
Marchese FP,Huarte Mdoi
10.1016/j.cell.2018.05.023subject
Has Abstractpub_date
2018-05-31 00:00:00pages
1318-1319issue
6eissn
0092-8674issn
1097-4172pii
S0092-8674(18)30635-4journal_volume
173pub_type
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