当前位置： SCI文献检索 > CELL期刊下所有文献 > Utilization of stored mRNA in Xenopus embryos and its replacement by newly synthesized transcripts: histone H1 synthesis using interspecies hybrids.

Utilization of stored mRNA in Xenopus embryos and its replacement by newly synthesized transcripts: histone H1 synthesis using interspecies hybrids.

Abstract：

:We studied H1 gene expression in hybrids of Xenopus laevis (female) x Xenopus borealis (male) and saw paternal H1 synthesis in mid-blastulae, which indicates that the H1 genes are active by this stage. The behavior of the maternal store of H1 histone mRNA was studied in androgenetic haploids. In which all stored mRNA is of the laevis type and all new transcripts are borealis. This showed that the initial activation of H1 synthesis occurs entirely by mobilizing maternal transcripts and that these are then unstable, disappearing in a few hours, by the early gastrula stage.

journal_name

Cell

journal_title

Cell

authors

Woodland HR,Flynn JM,Wyllie AJ

doi

10.1016/0092-8674(79)90365-9

subject

Has Abstract

pub_date

1979-09-01 00:00:00

pages

165-71

issue

1

eissn

0092-8674

issn

1097-4172

pii

0092-8674(79)90365-9

journal_volume

18

pub_type

杂志文章

相关文献

CELL文献大全
  • Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration.

    abstract：:Portions of the nascent chain are exposed to the lumen, the cytosol, or neither at different stages during the cotranslational integration of a protein into the ER membrane, as shown by compartment-specific collisional quenching of fluorophores incorporated into the polypeptide. The opening or closing of each end of t...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/s0092-8674(00)80311-6

    authors： Liao S,Lin J,Do H,Johnson AE

    更新日期：1997-07-11 00:00:00

  • Gut Microbiota Orchestrates Energy Homeostasis during Cold.

    abstract：:Microbial functions in the host physiology are a result of the microbiota-host co-evolution. We show that cold exposure leads to marked shift of the microbiota composition, referred to as cold microbiota. Transplantation of the cold microbiota to germ-free mice is sufficient to increase insulin sensitivity of the host...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2015.11.004

    authors： Chevalier C,Stojanović O,Colin DJ,Suarez-Zamorano N,Tarallo V,Veyrat-Durebex C,Rigo D,Fabbiano S,Stevanović A,Hagemann S,Montet X,Seimbille Y,Zamboni N,Hapfelmeier S,Trajkovski M

    更新日期：2015-12-03 00:00:00

  • Spinning the web of cell fate.

    abstract：:Spatiotemporal changes in nuclear lamina composition underlie cell-type-specific chromatin organization and cell fate, suggesting that the lamina forms a dynamic framework critical for genome function, cellular identity, and developmental potential. ...

    journal_title：Cell

    pub_type： 杂志文章,评审

    doi：10.1016/j.cell.2013.02.052

    authors： Van Bortle K,Corces VG

    更新日期：2013-03-14 00:00:00

  • In Praise of Descriptive Science: A Breath of Fresh AIRE.

    abstract：:Meyer et al. find that subjects lacking the AIRE gene, critical for self-tolerance in T lymphocytes, show a broad range of autoantibody specificities, which can have extremely high affinities. The data also suggest that some of these autoantibodies can, surprisingly, prevent some types of autoimmunity, particularly ty...

    journal_title：Cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.cell.2016.07.018

    authors： Davis MM

    更新日期：2016-07-28 00:00:00

  • COP1, an Arabidopsis regulatory gene, encodes a protein with both a zinc-binding motif and a G beta homologous domain.

    abstract：:Plant seedling development is capable of following 1 of 2 distinct morphogenic pathways: skotomorphogenesis in darkness and photomorphogenesis in light. Dark-grown Arabidopsis seedlings with recessive mutations at the constitutively photomorphogenic (COP1) locus indicate that the wild-type COP1 protein represses photo...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/0092-8674(92)90555-q

    authors： Deng XW,Matsui M,Wei N,Wagner D,Chu AM,Feldmann KA,Quail PH

    更新日期：1992-11-27 00:00:00

  • Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2.

    abstract：:We used the interaction trap, a yeast genetic selection for interacting proteins, to isolate human cyclin-dependent kinase interactor 1 (Cdi1). In yeast, Cdi1 interacts with cyclin-dependent kinases, including human Cdc2, Cdk2, and Cdk3, but not with Ckd4. In HeLa cells, Cdi1 is expressed at the G1 to S transition, an...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/0092-8674(93)90498-f

    authors： Gyuris J,Golemis E,Chertkov H,Brent R

    更新日期：1993-11-19 00:00:00

  • Structure of the guanine nucleotide exchange factor Sec7 domain of human arno and analysis of the interaction with ARF GTPase.

    abstract：:Sec7-related guanine nucleotide exchange factors (GEFs) initiate vesicle budding from the Golgi membrane surface by converting the GTPase ARF to a GTP-bound, membrane-associated form. Here we report the crystal structure of the catalytic Sec7 homology domain of Arno, a human GEF for ARF1, determined at 2.2 angstroms r...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/s0092-8674(00)80933-2

    authors： Mossessova E,Gulbis JM,Goldberg J

    更新日期：1998-02-06 00:00:00

  • Physiological and Genetic Adaptations to Diving in Sea Nomads.

    abstract：:Understanding the physiology and genetics of human hypoxia tolerance has important medical implications, but this phenomenon has thus far only been investigated in high-altitude human populations. Another system, yet to be explored, is humans who engage in breath-hold diving. The indigenous Bajau people ("Sea Nomads")...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2018.03.054

    authors： Ilardo MA,Moltke I,Korneliussen TS,Cheng J,Stern AJ,Racimo F,de Barros Damgaard P,Sikora M,Seguin-Orlando A,Rasmussen S,van den Munckhof ICL,Ter Horst R,Joosten LAB,Netea MG,Salingkat S,Nielsen R,Willerslev E

    更新日期：2018-04-19 00:00:00

  • Hybrid transfer RNA genes in phage T4.

    abstract：:We describe the isolation and characterization of two unusual amber suppressor forms of T4 tRNALeu. The sequences of the suppressor tRNAs can be described as hybrids of wild-type tRNALeu and suppressor tRNAGln molecules: the chain lengths and majority of the nucleotide residues corresponded to tRNALeu, but CUA anticod...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/0092-8674(84)90544-0

    authors： McClain WH,Foss K

    更新日期：1984-08-01 00:00:00

  • The XIST noncoding RNA functions independently of BRCA1 in X inactivation.

    abstract：:Females with germline mutations in BRCA1 are predisposed to develop breast and ovarian cancers. A previous report indicated that BRCA1 colocalizes with and is necessary for the correct localization of XIST, a noncoding RNA that coats the inactive X chromosome (Xi) to mediate formation of facultative heterochromatin. A...

    journal_title：Cell

    pub_type： 信件

    doi：10.1016/j.cell.2007.01.034

    authors： Xiao C,Sharp JA,Kawahara M,Davalos AR,Difilippantonio MJ,Hu Y,Li W,Cao L,Buetow K,Ried T,Chadwick BP,Deng CX,Panning B

    更新日期：2007-03-09 00:00:00

  • The Cdk-activating kinase (CAK) from budding yeast.

    abstract：:Activation of the cyclin-dependent kinases to promote cell cycle progression requires their association with cyclins as well as phosphorylation of a threonine (residue 161 in human p34cdc2). This phosphorylation is carried out by CAK, the Cdk-activating kinase. We have purified and cloned CAK from S. cerevisiae. Unlik...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/s0092-8674(00)80129-4

    authors： Kaldis P,Sutton A,Solomon MJ

    更新日期：1996-08-23 00:00:00

  • Adaptive immunity to SARS-CoV-2 and COVID-19.

    abstract：:The adaptive immune system is important for control of most viral infections. The three fundamental components of the adaptive immune system are B cells (the source of antibodies), CD4+ T cells, and CD8+ T cells. The armamentarium of B cells, CD4+ T cells, and CD8+ T cells has differing roles in different viral infect...

    journal_title：Cell

    pub_type： 杂志文章,评审

    doi：10.1016/j.cell.2021.01.007

    authors： Sette A,Crotty S

    更新日期：2021-01-12 00:00:00

  • A ribonucleolytic rat torpedoes RNA polymerase II.

    abstract：:Three recent papers reveal a fascinating link between pol II termination and ribonucleolytic decay of the nascent transcript by a 5'-3' exonuclease (yeast Rat1 and human Xrn2). The exonuclease travels with pol II and gains access to the nascent RNA after endonucleolytic cleavage at the poly(A) site or at a second cotr...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2004.11.041

    authors： Luo W,Bentley D

    更新日期：2004-12-29 00:00:00

  • Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin.

    abstract：:Treatment of guinea pig neutrophils with pertussis toxin (islet-activating protein; IAP) results in inhibition of N-formyl peptide receptor-mediated release of arachidonic acid and granular enzymes. Inhibition by the toxin is specific, in that responses to the calcium ionophore A23187 are not affected. The action of t...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/0092-8674(84)90008-4

    authors： Bokoch GM,Gilman AG

    更新日期：1984-12-01 00:00:00

  • ParB-type DNA Segregation Proteins Are CTP-Dependent Molecular Switches.

    abstract：:During cell division, newly replicated DNA is actively segregated to the daughter cells. In most bacteria, this process involves the DNA-binding protein ParB, which condenses the centromeric regions of sister DNA molecules into kinetochore-like structures that recruit the DNA partition ATPase ParA and the prokaroytic ...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2019.11.015

    authors： Osorio-Valeriano M,Altegoer F,Steinchen W,Urban S,Liu Y,Bange G,Thanbichler M

    更新日期：2019-12-12 00:00:00

  • Transmembrane location of oligosaccharide-lipid synthesis in microsomal vesicles.

    abstract：:The oligosaccharide-lipid which is the precursor of asparagine-linked oligosaccharides of eucaryotic glycoproteins is synthesized from sugar nucleotides in the endoplasmic reticulum. The transmembrane location of the assembly of this oligosaccharide-lipid has been studied in vitro in rat liver microsomes. Protease tre...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/0092-8674(80)90475-4

    authors： Snider MD,Sultzman LA,Robbins PW

    更新日期：1980-09-01 00:00:00

  • The transcription factor titration effect dictates level of gene expression.

    abstract：:Models of transcription are often built around a picture of RNA polymerase and transcription factors (TFs) acting on a single copy of a promoter. However, most TFs are shared between multiple genes with varying binding affinities. Beyond that, genes often exist at high copy number-in multiple identical copies on the c...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2014.02.022

    authors： Brewster RC,Weinert FM,Garcia HG,Song D,Rydenfelt M,Phillips R

    更新日期：2014-03-13 00:00:00

  • Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells.

    abstract：:Membrane subdomains have been implicated in T cell signaling, although their properties and mechanisms of formation remain controversial. Here, we have used single-molecule and scanning confocal imaging to characterize the behavior of GFP-tagged signaling proteins in Jurkat T cells. We show that the coreceptor CD2, th...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2005.04.009

    authors： Douglass AD,Vale RD

    更新日期：2005-06-17 00:00:00

  • Translational control by MAPK signaling in long-term synaptic plasticity and memory.

    abstract：:Enduring forms of synaptic plasticity and memory require new protein synthesis, but little is known about the underlying regulatory mechanisms. Here, we investigate the role of MAPK signaling in these processes. Conditional expression of a dominant-negative form of MEK1 in the postnatal murine forebrain inhibited ERK ...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/s0092-8674(04)00115-1

    authors： Kelleher RJ 3rd,Govindarajan A,Jung HY,Kang H,Tonegawa S

    更新日期：2004-02-06 00:00:00

  • Kinetics of transit of transferrin and epidermal growth factor through clathrin-coated membranes.

    abstract：:The kinetics of association of epidermal growth factor (EGF) and diferric-transferrin (TF) with clathrin-coated membranes of KB cells were examined using anti-clathrin antibody bound to Staphylococcus aureus. The ligands were bound to cells at 4 degrees C and after warming to 30 degrees C for 5 min, both ligands were ...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/0092-8674(84)90006-0

    authors： Hanover JA,Willingham MC,Pastan I

    更新日期：1984-12-01 00:00:00

  • Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses.

    abstract：:T cells expressing chimeric antigen receptors (CARs) are promising cancer therapeutic agents, with the prospect of becoming the ultimate smart cancer therapeutics. To expand the capability of CAR T cells, here, we present a split, universal, and programmable (SUPRA) CAR system that simultaneously encompasses multiple ...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2018.03.038

    authors： Cho JH,Collins JJ,Wong WW

    更新日期：2018-05-31 00:00:00

  • Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity.

    abstract：:The X-ray crystal structures of an anti-p24 (HIV-1) monoclonal antibody Fab fragment alone and in complexes with the epitope peptide GATPQDLNTnL (n = norleucine), an epitope-homologous peptide GATPEDLNQKLAGN, as well as two unrelated peptides GLYEWGGARITNTD and efslkGpllqwrsG (D-peptide), are presented to a maximum re...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/s0092-8674(00)80469-9

    authors： Keitel T,Kramer A,Wessner H,Scholz C,Schneider-Mergener J,Höhne W

    更新日期：1997-12-12 00:00:00

  • Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissue.

    abstract：:An antiserum against material shed into serum-free medium by MCF-7 human mammary carcinoma cells (anti-SFM II) disrupts cell-cell interactions in murine mammary tumor epithelial cells (MMTE). We now report purification of an 80 kd glycoprotein (GP80) from SFM of MCF-7 mammary carcinoma cells that blocks the activity o...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/0092-8674(83)90379-3

    authors： Damsky CH,Richa J,Solter D,Knudsen K,Buck CA

    更新日期：1983-09-01 00:00:00

  • Plant pathogens trick guard cells into opening the gates.

    abstract：:The stomata of plants regulate gas exchange and water transpiration in response to changing environmental conditions. New work reveals that stomata also have an important role in host defense. In this issue of Cell, Melotto et al. (2006) show that stomata close upon detection of potential microbial pathogens to preven...

    journal_title：Cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.cell.2006.08.020

    authors： Schulze-Lefert P,Robatzek S

    更新日期：2006-09-08 00:00:00

  • Statistical Detection of Relatives Typed with Disjoint Forensic and Biomedical Loci.

    abstract：:In familial searching in forensic genetics, a query DNA profile is tested against a database to determine whether it represents a relative of a database entrant. We examine the potential for using linkage disequilibrium to identify pairs of profiles as belonging to relatives when the query and database rely on nonover...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2018.09.008

    authors： Kim J,Edge MD,Algee-Hewitt BFB,Li JZ,Rosenberg NA

    更新日期：2018-10-18 00:00:00

  • Small RNAs of opposite sign… but same absolute value.

    abstract：:In ciliates, small RNAs have been shown to target foreign sequences for silencing via elimination from the somatic genome. Fang et al. now reveal a set of Piwi-interacting RNAs (piRNAs) in Oxytricha trifallax that likewise enable genomic self versus nonself discrimination, this time by specifying self sequences for ge...

    journal_title：Cell

    pub_type： 评论,杂志文章

    doi：10.1016/j.cell.2012.11.032

    authors： Sontheimer EJ

    更新日期：2012-12-07 00:00:00

  • Site-specific base substitution and deletion mutations that enhance or suppress transcription of the SV40 major late RNA.

    abstract：:Transcriptional analysis of SV40 late promoter mutants indicates that the DNA sequence 5'-GGTACCTAACC-3' (map positions 294-304) is important in the control of SV40 late RNA expression. C to T base substitutions at map positions 298, 299 and 304 increased initiation of late RNA synthesis at map position 325 five to te...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/0092-8674(82)90318-x

    authors： Brady J,Radonovich M,Vodkin M,Natarajan V,Thoren M,Das G,Janik J,Salzman NP

    更新日期：1982-12-01 00:00:00

  • ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner.

    abstract：:ATRX is an X-linked gene of the SWI/SNF family, mutations in which cause syndromal mental retardation and downregulation of α-globin expression. Here we show that ATRX binds to tandem repeat (TR) sequences in both telomeres and euchromatin. Genes associated with these TRs can be dysregulated when ATRX is mutated, and ...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2010.09.023

    authors： Law MJ,Lower KM,Voon HP,Hughes JR,Garrick D,Viprakasit V,Mitson M,De Gobbi M,Marra M,Morris A,Abbott A,Wilder SP,Taylor S,Santos GM,Cross J,Ayyub H,Jones S,Ragoussis J,Rhodes D,Dunham I,Higgs DR,Gibbons RJ

    更新日期：2010-10-29 00:00:00

  • Asynchronous switching of flagellar motors on a single bacterial cell.

    abstract：:Salmonella possesses several flagella, each capable of counterclockwise and clockwise rotation. Counterclockwise rotation produces swimming, clockwise rotation produces tumbling. Switching between senses occurs stochastically. The rotational sense of individual flagella on a single cell could be monitored under specia...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/0092-8674(83)90501-9

    authors： Macnab RM,Han DP

    更新日期：1983-01-01 00:00:00

  • Decoding the Genomics of Abdominal Aortic Aneurysm.

    abstract：:A key aspect of genomic medicine is to make individualized clinical decisions from personal genomes. We developed a machine-learning framework to integrate personal genomes and electronic health record (EHR) data and used this framework to study abdominal aortic aneurysm (AAA), a prevalent irreversible cardiovascular ...

    journal_title：Cell

    pub_type： 杂志文章

    doi：10.1016/j.cell.2018.07.021

    authors： Li J,Pan C,Zhang S,Spin JM,Deng A,Leung LLK,Dalman RL,Tsao PS,Snyder M

    更新日期：2018-09-06 00:00:00