Small RNAs of opposite sign… but same absolute value.

Abstract:

:In ciliates, small RNAs have been shown to target foreign sequences for silencing via elimination from the somatic genome. Fang et al. now reveal a set of Piwi-interacting RNAs (piRNAs) in Oxytricha trifallax that likewise enable genomic self versus nonself discrimination, this time by specifying self sequences for genome retention.

journal_name

Cell

journal_title

Cell

authors

Sontheimer EJ

doi

10.1016/j.cell.2012.11.032

subject

Has Abstract

pub_date

2012-12-07 00:00:00

pages

1157-8

issue

6

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(12)01417-1

journal_volume

151

pub_type

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