Plant pathogens trick guard cells into opening the gates.

Abstract:

:The stomata of plants regulate gas exchange and water transpiration in response to changing environmental conditions. New work reveals that stomata also have an important role in host defense. In this issue of Cell, Melotto et al. (2006) show that stomata close upon detection of potential microbial pathogens to prevent the infection of the leaf interior. Moreover, pathogenic bacteria have evolved strategies to suppress the closure of stomata.

journal_name

Cell

journal_title

Cell

authors

Schulze-Lefert P,Robatzek S

doi

10.1016/j.cell.2006.08.020

subject

Has Abstract

pub_date

2006-09-08 00:00:00

pages

831-4

issue

5

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(06)01087-7

journal_volume

126

pub_type

评论,杂志文章

相关文献

CELL文献大全
  • Correlation of specific keratins with different types of epithelial differentiation: monoclonal antibody studies.

    abstract::We have prepared three monoclonal antibodies against human epidermal keratins. These antibodies were highly specific for keratins and, in combination, recognized all major epidermal keratins of several mammalian species. We have used these antibodies to study the tissue distribution of epidermis-related keratins. In v...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/0092-8674(82)90234-3

    authors: Tseng SC,Jarvinen MJ,Nelson WG,Huang JW,Woodcock-Mitchell J,Sun TT

    更新日期:1982-09-01 00:00:00

  • Tiki casts a spell on Wnt.

    abstract::Negative feedback is a widespread feature of signaling pathways. In an unexpected twist described in this issue, He and colleagues identify a membrane-tethered metalloprotease named Tiki that inhibits Wnt signaling by removing an essential eight-residue fragment from Wnt itself. ...

    journal_title:Cell

    pub_type: 评论,杂志文章

    doi:10.1016/j.cell.2012.06.007

    authors: Vincent JP,Magee T

    更新日期:2012-06-22 00:00:00

  • Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.

    abstract::The cytosolic protein APAF1, human homolog of C. elegans CED-4, participates in the CASPASE 9 (CASP9)-dependent activation of CASP3 in the general apoptotic pathway. We have generated by gene trap a null allele of the murine Apaf1. Homozygous mutants die at embryonic day 16.5. Their phenotype includes severe craniofac...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/s0092-8674(00)81732-8

    authors: Cecconi F,Alvarez-Bolado G,Meyer BI,Roth KA,Gruss P

    更新日期:1998-09-18 00:00:00

  • Embryonic stem cell self-renewal, analyzed.

    abstract::Maintaining the pluripotency of mouse ES cells requires both LIF (leukemia inhibitory factor) and unknown factors in serum. The paper from Ying et al. in this issue of Cell shows that BMP (bone morphogenetic protein) can replace serum in this capacity, defining molecular requirements for ES cell self-renewal. ...

    journal_title:Cell

    pub_type: 评论,杂志文章

    doi:10.1016/s0092-8674(03)00853-5

    authors: Temple S

    更新日期:2003-10-31 00:00:00

  • GroEL1: a dedicated chaperone involved in mycolic acid biosynthesis during biofilm formation in mycobacteria.

    abstract::Mycobacteria are unusual in encoding two GroEL paralogs, GroEL1 and GroEL2. GroEL2 is essential--presumably providing the housekeeping chaperone functions--while groEL1 is nonessential, contains the attB site for phage Bxb1 integration, and encodes a putative chaperone with unusual structural features. Inactivation of...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2005.09.012

    authors: Ojha A,Anand M,Bhatt A,Kremer L,Jacobs WR Jr,Hatfull GF

    更新日期:2005-12-02 00:00:00

  • SGV1 encodes a CDC28/cdc2-related kinase required for a G alpha subunit-mediated adaptive response to pheromone in S. cerevisiae.

    abstract::The GPA1 gene of S. cerevisiae encodes a G alpha subunit that plays a positive role in the transduction of signals stimulating recovery from pheromone-induced cell cycle arrest. The GPA1Val50 mutation, in which Gly-50 is replaced by valine, causes hyperadaptation to pheromone. However, GPA1Val50 cells do not recover f...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/0092-8674(91)90386-d

    authors: Irie K,Nomoto S,Miyajima I,Matsumoto K

    更新日期:1991-05-31 00:00:00

  • A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response.

    abstract::Fragile X syndrome, a common form of inherited intellectual disability, is caused by loss of the fragile X mental retardation protein FMRP. FMRP is present predominantly in the cytoplasm, where it regulates translation of proteins that are important for synaptic function. We identify FMRP as a chromatin-binding protei...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2014.03.040

    authors: Alpatov R,Lesch BJ,Nakamoto-Kinoshita M,Blanco A,Chen S,Stützer A,Armache KJ,Simon MD,Xu C,Ali M,Murn J,Prisic S,Kutateladze TG,Vakoc CR,Min J,Kingston RE,Fischle W,Warren ST,Page DC,Shi Y

    更新日期:2014-05-08 00:00:00

  • Applied force reveals mechanistic and energetic details of transcription termination.

    abstract::Transcription termination by bacterial RNA polymerase (RNAP) occurs at sequences coding for a GC-rich RNA hairpin followed by a U-rich tract. We used single-molecule techniques to investigate the mechanism by which three representative terminators (his, t500, and tR2) destabilize the elongation complex (EC). For his a...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2008.01.027

    authors: Larson MH,Greenleaf WJ,Landick R,Block SM

    更新日期:2008-03-21 00:00:00

  • A B-lymphocyte-specific high-turnover protein: constitutive expression in resting B cells and induction of synthesis in proliferating cells.

    abstract::A basic B-cell-specific protein of 35,000 daltons (XM1) is expressed at a high rate--comparable to actin--in resting splenic B lymphocytes of various species. Splenic or thymic T cells or fibroblasts do not express this protein. Upon polyclonal stimulation of B lymphocytes or in proliferating B-lymphocyte-derived cell...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/0092-8674(82)90162-3

    authors: Rahmsdorf HJ,Mallick U,Ponta H,Herrlich P

    更新日期:1982-06-01 00:00:00

  • Histone acetyltransferase complexes stabilize swi/snf binding to promoter nucleosomes.

    abstract::To investigate the function of SWI/SNF in site-specific chromatin remodeling at promoters, we have used a purified system to analyze its distribution, function, and retention following recruitment by a sequence-specific transcription activator. Activator recruitment of SWI/SNF bound the complex to promoter proximal nu...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/s0092-8674(01)00279-3

    authors: Hassan AH,Neely KE,Workman JL

    更新日期:2001-03-23 00:00:00

  • Functional organization of the S. cerevisiae phosphorylation network.

    abstract::Reversible protein phosphorylation is a signaling mechanism involved in all cellular processes. To create a systems view of the signaling apparatus in budding yeast, we generated an epistatic miniarray profile (E-MAP) comprised of 100,000 pairwise, quantitative genetic interactions, including virtually all protein and...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2008.12.039

    authors: Fiedler D,Braberg H,Mehta M,Chechik G,Cagney G,Mukherjee P,Silva AC,Shales M,Collins SR,van Wageningen S,Kemmeren P,Holstege FC,Weissman JS,Keogh MC,Koller D,Shokat KM,Krogan NJ

    更新日期:2009-03-06 00:00:00

  • CRISPR-Cas9 knockin mice for genome editing and cancer modeling.

    abstract::CRISPR-Cas9 is a versatile genome editing technology for studying the functions of genetic elements. To broadly enable the application of Cas9 in vivo, we established a Cre-dependent Cas9 knockin mouse. We demonstrated in vivo as well as ex vivo genome editing using adeno-associated virus (AAV)-, lentivirus-, or parti...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2014.09.014

    authors: Platt RJ,Chen S,Zhou Y,Yim MJ,Swiech L,Kempton HR,Dahlman JE,Parnas O,Eisenhaure TM,Jovanovic M,Graham DB,Jhunjhunwala S,Heidenreich M,Xavier RJ,Langer R,Anderson DG,Hacohen N,Regev A,Feng G,Sharp PA,Zhang F

    更新日期:2014-10-09 00:00:00

  • Activation and repression of myogenesis in somatic cell hybrids: evidence for trans-negative regulation of MyoD in primary fibroblasts.

    abstract::We show that transfer of human fibroblast chromosome 11 (containing the human MyoD gene) from primary cells into 10T1/2 mouse fibroblasts by microcell fusion activates expression of the transferred human MyoD gene and converts these cells to myoblasts. Transfer of human chromosome 11 into B78 melanoma cells also leads...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/0092-8674(90)90285-m

    authors: Thayer MJ,Weintraub H

    更新日期:1990-10-05 00:00:00

  • A dynamically localized protease complex and a polar specificity factor control a cell cycle master regulator.

    abstract::Regulated proteolysis is essential for cell cycle progression in both prokaryotes and eukaryotes. We show here that the ClpXP protease, responsible for the degradation of multiple bacterial proteins, is dynamically localized to specific cellular positions in Caulobacter where it degrades colocalized proteins. The CtrA...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2005.12.033

    authors: McGrath PT,Iniesta AA,Ryan KR,Shapiro L,McAdams HH

    更新日期:2006-02-10 00:00:00

  • Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.

    abstract::Chromatin modifying activities inherent to polycomb repressive complexes PRC1 and PRC2 play an essential role in gene regulation, cellular differentiation, and development. However, the mechanisms by which these complexes recognize their target sites and function together to form repressive chromatin domains remain po...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2014.05.004

    authors: Blackledge NP,Farcas AM,Kondo T,King HW,McGouran JF,Hanssen LLP,Ito S,Cooper S,Kondo K,Koseki Y,Ishikura T,Long HK,Sheahan TW,Brockdorff N,Kessler BM,Koseki H,Klose RJ

    更新日期:2014-06-05 00:00:00

  • Self-eating limits EGFR-dependent tumor growth.

    abstract::Autophagy is a cell-autonomous, catabolic process that plays context-dependent roles in tumor growth and progression. Wei et al. report that EGFR signaling promotes tumor growth through phosphorylation and functional inactivation of Beclin 1 and the consequent suppression of autophagy. ...

    journal_title:Cell

    pub_type: 评论,杂志文章

    doi:10.1016/j.cell.2013.08.040

    authors: Fantin VR,Abraham RT

    更新日期:2013-09-12 00:00:00

  • A Mild PUM1 Mutation Is Associated with Adult-Onset Ataxia, whereas Haploinsufficiency Causes Developmental Delay and Seizures.

    abstract::Certain mutations can cause proteins to accumulate in neurons, leading to neurodegeneration. We recently showed, however, that upregulation of a wild-type protein, Ataxin1, caused by haploinsufficiency of its repressor, the RNA-binding protein Pumilio1 (PUM1), also causes neurodegeneration in mice. We therefore search...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2018.02.006

    authors: Gennarino VA,Palmer EE,McDonell LM,Wang L,Adamski CJ,Koire A,See L,Chen CA,Schaaf CP,Rosenfeld JA,Panzer JA,Moog U,Hao S,Bye A,Kirk EP,Stankiewicz P,Breman AM,McBride A,Kandula T,Dubbs HA,Macintosh R,Cardamone M

    更新日期:2018-02-22 00:00:00

  • A Call for Systematic Research on Solute Carriers.

    abstract::Solute carrier (SLC) membrane transport proteins control essential physiological functions, including nutrient uptake, ion transport, and waste removal. SLCs interact with several important drugs, and a quarter of the more than 400 SLC genes are associated with human diseases. Yet, compared to other gene families of s...

    journal_title:Cell

    pub_type: 杂志文章,评审

    doi:10.1016/j.cell.2015.07.022

    authors: César-Razquin A,Snijder B,Frappier-Brinton T,Isserlin R,Gyimesi G,Bai X,Reithmeier RA,Hepworth D,Hediger MA,Edwards AM,Superti-Furga G

    更新日期:2015-07-30 00:00:00

  • Metastatic potential: generic predisposition of the primary tumor or rare, metastatic variants-or both?

    abstract::Metastasis is a rare event. Does it arise from rare, variant, highly metastatic cells or does a primary tumor progress to a premalignant state from which metastases arise stochastically without further changes in gene expression? Arguments and evidence have been adduced to support either position. A paper in this mont...

    journal_title:Cell

    pub_type: 杂志文章,评审

    doi:10.1016/s0092-8674(03)00468-9

    authors: Hynes RO

    更新日期:2003-06-27 00:00:00

  • Ethylene prunes translation.

    abstract::Ethylene regulates many aspects of plant growth and development. In the presence of ethylene, the C terminus of EIN2 (EIN2C) translocates into the nucleus and activates transcription. Li et al. and Merchante et al. show that EIN2C also regulates translation through an interaction with the 3' UTRs of transcripts. ...

    journal_title:Cell

    pub_type: 评论,杂志文章

    doi:10.1016/j.cell.2015.10.032

    authors: Salehin M,Estelle M

    更新日期:2015-10-22 00:00:00

  • Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages.

    abstract::The cellular complexity and scale of the early liver have constrained analyses examining its emergence during organogenesis. To circumvent these issues, we analyzed 45,334 single-cell transcriptomes from embryonic day (E)7.5, when endoderm progenitors are specified, to E10.5 liver, when liver parenchymal and non-paren...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2020.09.012

    authors: Lotto J,Drissler S,Cullum R,Wei W,Setty M,Bell EM,Boutet SC,Nowotschin S,Kuo YY,Garg V,Pe'er D,Church DM,Hadjantonakis AK,Hoodless PA

    更新日期:2020-10-29 00:00:00

  • Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La lupus antibodies.

    abstract::The small ribonucleoproteins recognized by anti-La autoantibodies contain a heterogeneous mixture of small RNAs from uninfected mammalian cells. The identity of many of these has now been established by the discovery of precursor forms of 5S rRNA and of certain tRNAs among La RNAs from HeLa cells. The small fraction o...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/0092-8674(82)90099-x

    authors: Rinke J,Steitz JA

    更新日期:1982-05-01 00:00:00

  • Mitotic histone H3 phosphorylation by the NIMA kinase in Aspergillus nidulans.

    abstract::Phosphorylation of histone H3 serine 10 correlates with chromosome condensation and is required for normal chromosome segregation in Tetrahymena. This phosphorylation is dependent upon activation of the NIMA kinase in Aspergillus nidulans. NIMA expression also induces Ser-10 phosphorylation inappropriately in S phase-...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/s0092-8674(00)00035-0

    authors: De Souza CP,Osmani AH,Wu LP,Spotts JL,Osmani SA

    更新日期:2000-08-04 00:00:00

  • Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.

    abstract::The integration of mass spectrometry-based proteomics with next-generation DNA and RNA sequencing profiles tumors more comprehensively. Here this "proteogenomics" approach was applied to 122 treatment-naive primary breast cancers accrued to preserve post-translational modifications, including protein phosphorylation a...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2020.10.036

    authors: Krug K,Jaehnig EJ,Satpathy S,Blumenberg L,Karpova A,Anurag M,Miles G,Mertins P,Geffen Y,Tang LC,Heiman DI,Cao S,Maruvka YE,Lei JT,Huang C,Kothadia RB,Colaprico A,Birger C,Wang J,Dou Y,Wen B,Shi Z,Liao Y,Wizn

    更新日期:2020-11-25 00:00:00

  • SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality.

    abstract::SOCS1 is an SH2-containing protein that is primarily expressed in thymocytes in a cytokine- and T cell receptor-independent manner. SOCS1 deletion causes perinatal lethality with death by 2-3 weeks. During this period thymic changes include a loss of cellularity and a switch from predominantly CD4+ CD8+ to single posi...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/s0092-8674(00)80048-3

    authors: Marine JC,Topham DJ,McKay C,Wang D,Parganas E,Stravopodis D,Yoshimura A,Ihle JN

    更新日期:1999-09-03 00:00:00

  • The sequential action of miR156 and miR172 regulates developmental timing in Arabidopsis.

    abstract::The transition from the juvenile to the adult phase of shoot development in plants is accompanied by changes in vegetative morphology and an increase in reproductive potential. Here, we describe the regulatory mechanism of this transition. We show that miR156 is necessary and sufficient for the expression of the juven...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2009.06.031

    authors: Wu G,Park MY,Conway SR,Wang JW,Weigel D,Poethig RS

    更新日期:2009-08-21 00:00:00

  • Injection of mitochondria into human cells leads to a rapid replacement of the endogenous mitochondrial DNA.

    abstract::Isolated human mitochondria containing a mitochondrial DNA (mtDNA) coded chloramphenicol resistance marker were injected into cells from two different human sensitive cell lines, 143BTK- and HT1080-6TG, which had been partially depleted of their mtDNA by ethidium bromide treatment. On the basis of the available eviden...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/0092-8674(88)90423-0

    authors: King MP,Attardi G

    更新日期:1988-03-25 00:00:00

  • Acetate fuels the cancer engine.

    abstract::Cancer cells have distinctive nutrient demands to fuel growth and proliferation, including the disproportionate use of glucose, glutamine, and fatty acids. Comerford et al. and Mashimo et al. now demonstrate that several types of cancer are avid consumers of acetate, which facilitates macromolecular biosynthesis and h...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/j.cell.2014.12.009

    authors: Lyssiotis CA,Cantley LC

    更新日期:2014-12-18 00:00:00

  • Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein.

    abstract::A new type of mutation that affects a discrete step in the process of adsorptive endocytosis has been identified in one of 22 strains of fibroblasts derived from subjects with the clinical phenotype of homozygous familial hypercholesterolemia (FH). In this unique mutant strain (derived from subject J.D.), the cell sur...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/0092-8674(76)90130-6

    authors: Brown MS,Goldstein JL

    更新日期:1976-12-01 00:00:00

  • A chromosome RNAissance.

    abstract::In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification. ...

    journal_title:Cell

    pub_type: 杂志文章

    doi:10.1016/s0092-8674(02)01039-5

    authors: Dernburg AF,Karpen GH

    更新日期:2002-10-18 00:00:00