Abstract：
:Solute carrier (SLC) membrane transport proteins control essential physiological functions, including nutrient uptake, ion transport, and waste removal. SLCs interact with several important drugs, and a quarter of the more than 400 SLC genes are associated with human diseases. Yet, compared to other gene families of similar stature, SLCs are relatively understudied. The time is right for a systematic attack on SLC structure, specificity, and function, taking into account kinship and expression, as well as the dependencies that arise from the common metabolic space.
journal_name
Celljournal_title
Cellauthors
César-Razquin A,Snijder B,Frappier-Brinton T,Isserlin R,Gyimesi G,Bai X,Reithmeier RA,Hepworth D,Hediger MA,Edwards AM,Superti-Furga Gdoi
10.1016/j.cell.2015.07.022subject
Has Abstractpub_date
2015-07-30 00:00:00pages
478-87issue
3eissn
0092-8674issn
1097-4172pii
S0092-8674(15)00899-5journal_volume
162pub_type
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