Abstract:
:Cancer cells have distinctive nutrient demands to fuel growth and proliferation, including the disproportionate use of glucose, glutamine, and fatty acids. Comerford et al. and Mashimo et al. now demonstrate that several types of cancer are avid consumers of acetate, which facilitates macromolecular biosynthesis and histone modification.
journal_name
Celljournal_title
Cellauthors
Lyssiotis CA,Cantley LCdoi
10.1016/j.cell.2014.12.009subject
Has Abstractpub_date
2014-12-18 00:00:00pages
1492-4issue
7eissn
0092-8674issn
1097-4172pii
S0092-8674(14)01579-7journal_volume
159pub_type
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