Abstract:
:The recent emergence and rapid global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pose an unprecedented medical and socioeconomic crisis, and the disease caused by it, Coronavirus disease 2019 (COVID-19), was declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Chinese scientists and physicians rapidly identified the causative pathogen, which turned out to be a novel betacoronavirus with high sequence similarities to bat and pangolin coronaviruses. The scientific community has ignited tremendous efforts to unravel the biological underpinning of SARS-CoV-2, which constitutes the foundation for therapy and vaccine development strategies. Here, we summarize the current state of knowledge on the genome, structure, receptor, and origin of SARS-CoV-2.
journal_name
Virol Sinjournal_title
Virologica Sinicaauthors
Wang S,Trilling M,Sutter K,Dittmer U,Lu M,Zheng X,Yang D,Liu Jdoi
10.1007/s12250-020-00298-zsubject
Has Abstractpub_date
2020-12-01 00:00:00pages
673-684issue
6eissn
1674-0769issn
1995-820Xpii
10.1007/s12250-020-00298-zjournal_volume
35pub_type
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