Effect of periodontal surgery on osteoprotegerin levels in gingival crevicular fluid, saliva, and gingival tissues of chronic periodontitis patients.

abstract：:The present study evaluated diurnal variations and day-to-day fluctuations of salivary oxidative stress (OS) markers in healthy adult individuals. Whole unstimulated saliva was collected at 2 time intervals over 3 consecutive days. Glutathione peroxidase (GPX), superoxide dismutase (SOD), total antioxidant capacity (T...

journal_title：Disease markers

authors： Alajbeg IZ,Lapić I,Rogić D,Vuletić L,Andabak Rogulj A,Illeš D,Knezović Zlatarić D,Badel T,Vrbanović E,Alajbeg I

更新日期：2017-01-01 00:00:00

abstract：AIM:The purpose of this study is to determine the association between eotaxin 426 C/T, -384 A/G, 67 G/A, eNOS -786 T/C, 4 a/b, and MMP-13 rs640198 G/T and prognosis of patients with known CAD. METHODS:From total of 1161 patients referred to coronary angiography, 532 patients with angiographically confirmed CAD were se...

journal_title：Disease markers

authors： Kincl V,Máchal J,Drozdová A,Panovský R,Vašků A

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Both adaptive and innate immune systems are involved in coronary artery disease (CAD). The aim of this study was to evaluate TH17 cytokines expression profiles in un-stimulated peripheral blood lymphocytes (PBMCs) of patients with coronary artery disease. METHODS:Expression profiles of IL-17, IL-23, and TGF-...

journal_title：Disease markers

authors： Khojasteh-Fard M,Abolhalaj M,Amiri P,Zaki M,Taheri Z,Qorbani M,Bazzaz JT,Amoli MM

更新日期：2012-01-01 00:00:00

abstract：AIM:To assess and compare the roles of plasma and urine concentrations of neutrophil gelatinase associated lipocalin (NGAL) and Cystatin C for early diagnosis of septic acute kidney injury (AKI) in adult critically ill patients. METHODS:Patients were divided into three groups as sepsis-non AKI, sepsis-AKI and non seps...

journal_title：Disease markers

authors： Aydoğdu M,Gürsel G,Sancak B,Yeni S,Sarı G,Taşyürek S,Türk M,Yüksel S,Senes M,Ozis TN

更新日期：2013-01-01 00:00:00

abstract：:Recent experiments have shown that when specific biomolecular interactions are confined to one surface of a microcantilever beam, changes in intermolecular nanomechanical forces provide sufficient differential torque to bend the cantilever beam. This has been used to detect single base pair mismatches during DNA hybri...

journal_title：Disease markers

authors： Majumdar A

更新日期：2002-01-01 00:00:00

abstract：:Alterations of the retinoblastoma (Rb) gene have been described in several human neoplasms and recently, it has been suggested that these alterations may play a role in the development of endometrial carcinomas. Paraffin sections from 31 cases of normal endometrium (16 proliferative, 15 secretory), 35 hyperplastic les...

journal_title：Disease markers

authors： Ioachim EE,Goussia AC,Kitsiou EG,Charalabopoulos K,Mermiga E,Stefanaki S

更新日期：2002-01-01 00:00:00

abstract：:IgA nephropathy is diagnosed by renal biopsy, an invasive procedure with a risk of significant complications. Noninvasive approaches are needed for possible diagnostic purposes and especially for monitoring disease activity or responses to treatment. In this pilot project, we assessed the utility of urine samples as s...

journal_title：Disease markers

authors： Neprasova M,Maixnerova D,Novak J,Reily C,Julian BA,Boron J,Novotny P,Suchanek M,Tesar V,Kacer P

更新日期：2016-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection prevalence was determined in 34 hepatocellular carcinoma (HCC) patients with underlying liver cirrhosis. Serum alfa-fetoprotein level was found to be more than 1000 ng/ml (3153 +/- 1451) in those patients. Anti-HCV antibodies were detected in 84% of patients sera negative for hepatiti...

journal_title：Disease markers

authors： Mabrouk GM

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Stroke subtype diagnosis leads to specific therapies to reduce recurrences. Because nearly one third of patients remain with unknown etiology after a complete screening workup, we aim to investigate whether molecular markers of myocardial damage were associated with cardioembolic stroke and if they were usef...

journal_title：Disease markers

authors： Rodríguez-Yáñez M,Sobrino T,Blanco M,de la Ossa NP,Brea D,Rodríguez-González R,Leira R,Dávalos A,Castillo J

更新日期：2009-01-01 00:00:00

abstract：:In order to develop reagents that can detect the exposed core carbohydrate antigens of mucins, we have prepared monoclonal antibodies against partially deglycosylated LS174T human colon cancer mucin. The three monoclonal antibodies, 10F4, 15D3a, and 91S8, stained cancers of the colon, pancreas, stomach, breast, prosta...

journal_title：Disease markers

authors： Huang J,Byrd JC,Siddiki B,Yuan M,Lau E,Kim YS

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVE:The purpose of the present study is to explore the correlation between nuclear expression of cyclin-dependent kinase inhibitor 1B (p27) and clinicopathologic features in nasopharyngeal carcinoma (NPC), including patient survival. METHODS:Immunohistochemistry was used to examine the expression of p27 in 130 p...

journal_title：Disease markers

authors： Liu Z,Long Y,Zhang Y,Huang W,Long X,Yang H,Long J,Cheng C,Fang W

更新日期：2013-01-01 00:00:00

abstract：Aim:To evaluate the diagnosis value of serum human epididymis protein 4 (HE4), cancer antigen 125 (CA125), the Risk of Ovarian Malignancy Algorithm (ROMA), and Copenhagen Index (CPH-I) at early stages for differentiating borderline ovarian tumors from epithelial ovarian cancer. Methods:We recruited 144 borderline ovar...

journal_title：Disease markers

authors： Wang Z,Tao X,Ying C

更新日期：2019-10-13 00:00:00

abstract：BACKGROUND:Soluble vascular endothelial growth factor (VEGF) is a promising biomarker in monitoring rheumatoid arthritis (RA), but studies of pre-analytical and biologic variability are few. METHODS:VEGF was measured by ELISA methods in serum and plasma from healthy persons and RA patients. Pre-analytical factors were...

journal_title：Disease markers

authors： Hetland ML,Christensen IJ,Lottenburger T,Johansen JS,Svendsen MN,Hørslev-Petersen K,Nielsen L,Nielsen HJ

更新日期：2008-01-01 00:00:00

abstract：:The adenosine deaminase gene frequencies were calculated in 405 subjects randomly chosen from the Bigouden district. A rather high frequency (0.0765 +/- 0.0093) was found for the ADA2 gene. The possible effect of Celtic influences is considered. ...

journal_title：Disease markers

authors： Youinou P,Seger J,Salmon D,Jouquan J,le Menn G,Ruffie J,Salmon C

更新日期：1988-03-01 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology, characterized by injury of the intrahepatic bile ducts that may eventually lead to cirrhosis and liver failure. Evidence suggests cardinal roles for both environmental factors and genetic susceptibilit...

journal_title：Disease markers

authors： Kumagi T,Abe M,Ikeda Y,Hiasa Y

更新日期：2010-01-01 00:00:00

abstract：:Gastric cancer is the fifth most common cancer and the third leading cause of cancer-related death, whose patterns vary among geographical regions and ethnicities. It is a multifactorial disease, and its development depends on infection by Helicobacter pylori (H. pylori) and Epstein-Barr virus (EBV), host genetic fact...

journal_title：Disease markers

authors： Sandoval-Bórquez A,Saavedra K,Carrasco-Avino G,Garcia-Bloj B,Fry J,Wichmann I,Corvalán AH

更新日期：2015-01-01 00:00:00

abstract：:PD1/PDL1 inhibitors have been adopted for the treatment of advanced non-small-cell lung cancer, and PDL1 expression has been investigated as a predictive biomarker for PD1/PDL1 inhibitor therapy. However, PDL1 lacks diagnostic accuracy in differentiating patients who are likely or unlikely to benefit. So, it is urgent...

journal_title：Disease markers

authors： Wu Y,Lin L,Liu X

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:Up to 43% of HIV-infected patients co-infected with Mycobacterium tuberculosis experience exacerbations of tuberculosis (TB) after commencing antiretroviral therapy (ART). These are termed immune restoration disease (IRD). It is unclear why individual susceptibility varies. OBJECTIVE:We investigate if singl...

journal_title：Disease markers

authors： Affandi JS,Kumar M,Agarwal U,Singh S,Price P

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the combined effects of MMP-2 and TIMP-2 protein immunoreactivities on the prognosis in endometrial carcinoma. METHODS:Paraffin-embedded tissue samples from 225 primary endometrioid adenocarcinomas and 13 histologies other than endometrioid adenocarcinoma were immunohist...

journal_title：Disease markers

authors： Honkavuori-Toivola M,Santala M,Soini Y,Turpeenniemi-Hujanen T,Talvensaari-Mattila A

更新日期：2013-01-01 00:00:00

abstract：:The surface and cytoplasmic expression of CD1a molecules was analysed by indirect immunofluorescence (IIF) and dot blot assay (DBA) in a panel of 40 acute and chronic leukaemias. Thirty-two per cent of the samples were positive by IIF but, surprisingly, 72 per cent of the patients were positive by DBA, suggesting the ...

journal_title：Disease markers

authors： Salamone MC,Roisman FR,Morelli AE,Noli MI,Fainboim L

更新日期：1990-09-01 00:00:00

abstract：Background and Objective:Reduced expression of syndecan-1 (CD138), increased proliferation index, and modifications in the expression of the molecular RANK/RANKL/OPG triad are related to an intensified potential of aggressiveness and invasion of diverse tumors and cysts. The aim was to compare the expression of Ki-67, ...

journal_title：Disease markers

authors： Brito-Mendoza L,Bologna-Molina R,Irigoyen-Camacho ME,Martinez G,Sánchez-Romero C,Mosqueda-Taylor A

更新日期：2018-07-29 00:00:00

abstract：:Plasma from bronchial asthma patients and healthy controls was investigated for the content of lipoxygenase products. After lipid extraction using SEP-PAK C18 Cartridges, the lipoxygenase products were measured by Enzyme-Immunoassay. Elevated chemotactic B4 was found in plasma from asthmatic patients with mean value (...

journal_title：Disease markers

authors： Mansour M,Farouk N,el Maragy A,Radwan I,el-Ahmady O

更新日期：1995-03-01 00:00:00

abstract：:Twelve multiplex families with isolated congenital heart diseases (CHD) were included in the study. In 9 families the types of CHD in the living sibs were concordant and in the other 3 were discordant. All families were subjected to the following: (1) Pedigree construction, (2) clinical examination of the parents, aff...

journal_title：Disease markers

authors： Hafez M,Abdalla A,el-Shennawy F,Tawfik SH

更新日期：1986-12-01 00:00:00

abstract：:INHBA-encoded inhibin β A is a member of the transforming growth factor-β (TGF-β) superfamily. INHBA has been reported to be implicated in the progression of multiple types of cancer including ovarian cancer (OC). However, the mechanisms by which INHBA affects OC progression are not well-characterized. The aim of our ...

journal_title：Disease markers

authors： Li X,Yang Z,Xu S,Wang Z,Jin P,Yang X,Zhang Z,Wang Y,Wei X,Fang T,Gao Q

更新日期：2019-11-11 00:00:00

abstract：:Microsatellite instability (MSI) analysis is becoming more and more important to detect sporadic primary tumors of the MSI phenotype as well as in helping to determine Hereditary Non-Polyposis Colorectal Cancer (HNPCC) cases. After some years of conflicting data due to the absence of consensus markers for the MSI phen...

journal_title：Disease markers

authors： Buhard O,Suraweera N,Lectard A,Duval A,Hamelin R

更新日期：2004-01-01 00:00:00

abstract：:Purpose. The aim of this study was to evaluate the sensitivity of pleural C-reactive protein (CRP) biomarker levels in identifying parapneumonic effusions. Methods. A single-center, retrospective review of 244 patients diagnosed with pleural effusions was initiated among patients at the Rabin Medical Center, Petah Tik...

journal_title：Disease markers

authors： Izhakian S,Wasser WG,Fox BD,Vainshelboim B,Kramer MR

更新日期：2016-01-01 00:00:00

abstract：:Colorectal cancer (CRC) is a complex and heterogeneous disease with four consensus molecular subtypes (CMS1-4). LTBP2 is a member of the fibrillin/LTBP super family and plays a critical role in tumorigenesis by activating TGF-β in the CMS4 CRC subtype. So far, the expression and prognostic significance of LTBP2 in CRC...

journal_title：Disease markers

authors： Huang Y,Wang G,Zhao C,Geng R,Zhang S,Wang W,Chen J,Liu H,Wang X

更新日期：2019-03-10 00:00:00

abstract：BACKGROUND:A novel swine-origin influenza A H1N1 virus (S-OIV) caused human infection and acute respiratory illness in 2009, resulting in an influenza pandemic. OBJECTIVES:This study characterized the immune responses of S-OIV infection in pediatric patients at risk of pulmonary complications. METHODS:All enrolled pe...

journal_title：Disease markers

authors： Wang SM,Liao YT,Hu YS,Ho TS,Shen CF,Wang JR,Lin YS,Liu CC

更新日期：2014-01-01 00:00:00

abstract：Aim:B7-H4 is member of the B7 family that negatively regulates the immune response, which are associated with tumor development and prognosis. The present study is aimed at examining serum B7-H4 expression and exploring its contribution to diagnosis in patients with colorectal cancer. Methods:We determined serum expre...

journal_title：Disease markers

authors： Wang P,Li C,Zhang F,Ma X,Gai X

更新日期：2018-09-27 00:00:00

abstract：:In recent researches, high expression of nesfatin-1/nucleobindin-2 (NUCB2) is linked to poor prognosis in prostate and colon cancer due to the enhancement in proliferation, migration, and invasion. However, the role of nesfatin-1 in bladder cancer is not clear. In this study, we examined the expression of NUCB2 in bla...

journal_title：Disease markers

authors： Liu GM,Xu ZQ,Ma HS

更新日期：2018-09-19 00:00:00