Immunophenotype expressions and cytokine profiles of influenza A H1N1 virus infection in pediatric patients in 2009.

abstract：:The discovery that PSA exists in serum in both free and complexed forms led to development of immunoassays specific for different PSA forms. This helped in measuring free PSA in the presence of PSA-ACT (PSA-alpha antichymotrypsin), hence it was possible to calculate the percent free PSA or free to total PSA ratio, mea...

journal_title：Disease markers

authors： Thakur V,Singh PP,Talwar M,Mukherjee U

更新日期：2003-01-01 00:00:00

abstract：:In order to develop reagents that can detect the exposed core carbohydrate antigens of mucins, we have prepared monoclonal antibodies against partially deglycosylated LS174T human colon cancer mucin. The three monoclonal antibodies, 10F4, 15D3a, and 91S8, stained cancers of the colon, pancreas, stomach, breast, prosta...

journal_title：Disease markers

authors： Huang J,Byrd JC,Siddiki B,Yuan M,Lau E,Kim YS

更新日期：1992-03-01 00:00:00

abstract：:Cardiovascular diseases are the main causes of mortality. Sudden cardiac death may also appear in athletes, due to underlying congenital or inherited cardiac abnormalities. The electrocardiogram is used in clinical practice and clinical trials, as a valid, reliable, accessible, inexpensive method. The aim of the prese...

journal_title：Disease markers

authors： Mozos I,Caraba A

更新日期：2015-01-01 00:00:00

abstract：Objective:To evaluate the performance of serum and urinary sCD163 concentrations as possible biomarker in systemic sclerosis (SSc). Methods:Urine and serum samples were obtained from SSc patients and age- and sex-matched controls. Serum and urinary sCD163 concentrations were measured by commercially available ELISA ki...

journal_title：Disease markers

authors： Frantz C,Pezet S,Avouac J,Allanore Y

更新日期：2018-04-01 00:00:00

abstract：:Restriction fragment length polymorphism (RFLP) analyses of DR1 positive peripheral blood leukocytes DNA was carried out. The Taq I digested DNA was hybridized with cDNA probes for HLA-DR and -DQ beta genes. The DR probe detected fragments commonly observed in the DR1 specificity, whereas a new DQ-beta fragment was de...

journal_title：Disease markers

authors： Redford A,Magalong D,Onohara-Toyoda M,Tyan D,Riley WJ,Maclaren NK,Rotter JI,Toyoda H

更新日期：1991-09-01 00:00:00

abstract：Background:The pathogenesis of thoracic aortopathy is complex, and much evidence suggests the influence of genetic factors. Some genes with polymorphisms are widely considered critical factors in the initiation and development of aortic aneurysm. The aim of our study was to analyze the association of genetic polymorphi...

journal_title：Disease markers

authors： Gorący I,Grudniewicz S,Safranow K,Ciechanowicz A,Jakubiszyn P,Gorący A,Brykczyński M

更新日期：2020-09-24 00:00:00

abstract：Background:Syndecan-1 (SDC1/CD138) is a key cell surface adhesion molecule essential for maintaining cell morphology and the interactions with the surrounding microenvironment. SDC1 tumor immunoexpression may be increased or decreased in epithelial malignant neoplasms compared to that in adjacent non-neoplastic tissue,...

journal_title：Disease markers

authors： Li K,Li L,Wu X,Yu J,Ma H,Zhang R,Li Y,Wang W

更新日期：2019-04-30 00:00:00

abstract：:IGF2 is the first gene discovered to be imprinted and expressed exclusively from the paternal allele in both human and mouse. IGF2 is also the first imprinted gene displaying loss of imprinting (LOI) or aberrant imprinting in human cancers. Evidently, LOI or reactivation of the maternal allele of IGF2 is associated wi...

journal_title：Disease markers

authors： Cui H

更新日期：2007-01-01 00:00:00

abstract：Objective:This study aimed to explore the associations between carotid intima-media thickness (CIMT) and early-stage diabetic kidney disease (DKD) coupled with Helicobacter pylori (H. pylori) infection in type 2 diabetic patients. Methods:A cross-sectional study including 180 type 2 diabetic participants was conducted...

journal_title：Disease markers

authors： Feng L,Deng C,Li Y

更新日期：2018-04-16 00:00:00

abstract：:Background. Early identification of high risk subjects for cardiovascular disease in health check-up is still unmet medical need. Cardiovascular disease is characterized by the superior increase in aspartate aminotransferase (AST) to alanine aminotransferase (ALT). However, the association of AST/ALT ratio with brain ...

journal_title：Disease markers

authors： Yokoyama M,Watanabe T,Otaki Y,Takahashi H,Arimoto T,Shishido T,Miyamoto T,Konta T,Shibata Y,Daimon M,Ueno Y,Kato T,Kayama T,Kubota I

更新日期：2016-01-01 00:00:00

abstract：:Ovarian cancer is complex disease composed of different histological grades and types. However, the underlying molecular mechanisms involved in the development of different phenotypes remain largely unknown. Epidemiological studies identified multiple exogenous and endogenous risk factors for ovarian cancer developmen...

journal_title：Disease markers

authors： Mok SC,Kwong J,Welch WR,Samimi G,Ozbun L,Bonome T,Birrer MJ,Berkowitz RS,Wong KK

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). METHODS:98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies ...

journal_title：Disease markers

authors： Demarco AL,Rodrigues Mde L,Figueiredo JF,Deghaide NH,de Menezes MB,Demarco LA,Fernandes AP,Donadi EA

更新日期：2012-01-01 00:00:00

abstract：:In view of the potential uses of cell surface tumour associated antigens in novel anticancer treatment, a study was designed to investigate whether the biological response modifiers interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) could effect the expression of an epitope on the tumour associa...

journal_title：Disease markers

authors： Clark S,McGuckin MA,Hurst T,Ward BG

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Soluble vascular endothelial growth factor (VEGF) is a promising biomarker in monitoring rheumatoid arthritis (RA), but studies of pre-analytical and biologic variability are few. METHODS:VEGF was measured by ELISA methods in serum and plasma from healthy persons and RA patients. Pre-analytical factors were...

journal_title：Disease markers

authors： Hetland ML,Christensen IJ,Lottenburger T,Johansen JS,Svendsen MN,Hørslev-Petersen K,Nielsen L,Nielsen HJ

更新日期：2008-01-01 00:00:00

abstract：:The human papilloma virus (HPV) associated with hyperplastic epithelium in an oral denture fibroma was examined by southern blot hybridization. Extracted DNA was hybridized with full length linear HPV type 2a, 6b, 11, 16, 18, 31 and 33 DNAs as a mixed probe only under low stringent conditions. The hybridized bands dig...

journal_title：Disease markers

authors： Yamaguchi T,Shindoh M,Amemiya A,Notani K,Fukuda H,Sakaoka H,Inoue M,Fujinaga K

更新日期：1997-04-01 00:00:00

abstract：Background:Cardiovascular disease (CVD) risks persist in patients despite the use of conventional treatments. This might be due to chronic inflammation as reflected in epidemiological studies associating circulating low-grade inflammatory markers with CVD recurrent events. Here, we explored this potential link by asses...

journal_title：Disease markers

authors： Khadir A,Kavalakatt S,Dehbi M,Alarouj M,Bennakhi A,Tiss A,Elkum N

更新日期：2018-12-13 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/2138627.]. ...

journal_title：Disease markers

authors： Marrugal Á,Ojeda L,Paz-Ares L,Molina-Pinelo S,Ferrer I

更新日期：2018-07-08 00:00:00

abstract：Background:We have previously shown that the deficiency of the gut enzyme intestinal alkaline phosphatase (IAP) is associated with type 2 diabetes mellitus (T2DM) in humans, and mice deficient in IAP develop the metabolic syndrome, a precipitant of T2DM and ischemic heart disease (IHD). We hypothesized that IAP deficie...

journal_title：Disease markers

authors： Malo J,Alam MJ,Shahnaz M,Kaliannan K,Chandra G,Aziz T,Sarker T,Bala M,Paul R,Saha CK,Karmakar PK,Malo MS

更新日期：2019-12-13 00:00:00

abstract：Purpose:To determine the frequency of the genotype of signal transducer and activator of transcription protein 3 (STAT3) rs744166, sirtuin (SIRT1) rs12778366, fibroblast growth factor (FGFR2) rs2981582, and advanced glycosylation end product-specific receptor (RAGE) rs1800625 gene polymorphisms in patients with larynge...

journal_title：Disease markers

authors： Uloza V,Tamauskaite T,Vilkeviciute A,Pasvenskaite A,Liutkevicius V,Liutkeviciene R

更新日期：2019-11-12 00:00:00

abstract：OBJECTIVES:Increases in red blood cell distribution width (RDW) and NT-proBNP (N-terminal pro-B-type natriuretic peptide) predict the mortality of chronic heart failure patients undergoing cardiac resynchronization therapy (CRT). It was hypothesized that RDW is independent of and possibly even superior to NT-proBNP fro...

journal_title：Disease markers

authors： Boros AM,Perge P,Jenei Z,Karády J,Zima E,Molnár L,Becker D,Gellér L,Prohászka Z,Merkely B,Széplaki G

更新日期：2016-01-01 00:00:00

abstract：:CD4+ T cells of patients with B cell non-Hodgkin's lymphoma (NHL) were analysed for expression of CD45RA and CD29. It was found that CD45RA expression was significantly lower, and CD29 expression significantly higher, in lymphoma patients compared to normal controls. Moreover absolute numbers of CD4+ T cells were sign...

journal_title：Disease markers

authors： Sewell HF,MacKenzie RH,Dawson AA,Ratcliffe MA,King DJ,Bennett NB

更新日期：1990-05-01 00:00:00

abstract：:Nevirapine (NVP) is an effective nonnucleoside reverse transcriptase inhibitor (NNRTI) of particular interest as it is often used in resource limited countries. However, one of the main concerns with the use of NVP is hepatotoxicity and elevation of liver enzymes as a consequence of highly active antiretroviral therap...

journal_title：Disease markers

authors： Wongtrakul J,Thongtan T,Roytrakul S,Kumrapich B,Janphen K,Praparattanapan J,Supparatpinyo K,Smith DR

更新日期：2014-01-01 00:00:00

abstract：Background:Preeclamptic pregnancies often present an intensified inflammatory state associated with the nuclear activity of NFκB. NEMO is an essential regulator of nuclear factor kappa B (NFκB) in cytoplasmic and nuclear cellular compartments. The aim of the present study is to examine the level and localization of the...

journal_title：Disease markers

authors： Sakowicz A,Lisowska M,Biesiada L,Płuciennik E,Gach A,Rybak-Krzyszkowska M,Huras H,Sakowicz B,Romanowicz H,Piastowska-Ciesielska AW,Grzesiak M,Pietrucha T

更新日期：2019-01-02 00:00:00

abstract：Objective:Several serum markers were reported to reflect the severity of pulmonary alveolar proteinosis (PAP). The aim of this study is to investigate a reliable and facile marker to access and monitor the clinical course of PAP in a large cohort. Methods:PAP patients from January 2010 to June 2018 were enrolled. Hosp...

journal_title：Disease markers

authors： Shi S,Chen L,Qiu X,Zhao Q,Xiao Y,Yan X

更新日期：2019-11-11 00:00:00

abstract：:Cyclin-dependent kinase regulatory subunit 2 (CKS2) is a member of the cell cycle-dependent protein kinase subunit family, which is implicated as an oncogene in various malignancies. However, the clinical significance, oncogenic functions, and related mechanisms of CKS2 in hepatocellular carcinoma (HCC) remain largely...

journal_title：Disease markers

authors： Zhang J,Song Q,Liu J,Lu L,Xu Y,Zheng W

更新日期：2019-10-22 00:00:00

abstract：:Exhaled breath condensate (EBC) has been increasingly used as a new and non-invasive method to study airway inflammation. In this study we have compared the concentrations of lipid mediators in EBC with concentrations in bronchoalveolar lavage fluid (BALF). We included 37 patients undergoing bronchoscopy (12 sarcoidos...

journal_title：Disease markers

authors： Antczak A,Piotrowski W,Marczak J,Ciebiada M,Gorski P,Barnes PJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Papillary thyroid carcinoma (PTC), follicular thyroid adenoma (FTA), and thyroid nodular hyperplasia (TNH) are the most frequent diseases of the thyroid gland. Previous studies described the involvement of dipeptidyl-peptidase IV (DPPIV/CD26) in the development of thyroid neoplasia and proposed it as an addi...

journal_title：Disease markers

authors： Larrinaga G,Blanco L,Errarte P,Beitia M,Sanz B,Perez I,Irazusta A,Sánchez CE,Santaolalla F,Andrés L,López JI

更新日期：2013-01-01 00:00:00

abstract：:Recent experiments have shown that when specific biomolecular interactions are confined to one surface of a microcantilever beam, changes in intermolecular nanomechanical forces provide sufficient differential torque to bend the cantilever beam. This has been used to detect single base pair mismatches during DNA hybri...

journal_title：Disease markers

authors： Majumdar A

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Elevated humoral responses to cytomegalovirus (CMV) associate with increased risk of cardiovascular disease (CVD) in HIV patients on antiretroviral therapy (ART). To better understand the persistence of CMV humoral responses in relation to CVD, we determined trends in CMV antibody levels over the first 10 ye...

journal_title：Disease markers

authors： Brunt SJ,Lee S,D'Orsogna L,Bundell C,Burrows S,Price P

更新日期：2014-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) are a class of small, non-coding RNA molecules that can regulate gene expression, thereby affecting crucial processes in cancer development. miRNAs offer great potential as biomarkers for cancer detection because of their remarkable stability in blood and their characteristic expression in different...

journal_title：Disease markers

authors： Mar-Aguilar F,Mendoza-Ramírez JA,Malagón-Santiago I,Espino-Silva PK,Santuario-Facio SK,Ruiz-Flores P,Rodríguez-Padilla C,Reséndez-Pérez D

更新日期：2013-01-01 00:00:00