CPH-I and HE4 Are More Favorable Than CA125 in Differentiating Borderline Ovarian Tumors from Epithelial Ovarian Cancer at Early Stages.

abstract：:Traditional lipid measures are the cornerstone of risk assessment and treatment goals in cardiovascular prevention. Whereas the association between total, LDL-, HDL-cholesterol and cardiovascular disease risk has been generally acknowledged, the rather poor capacity to distinguish between patients who will and those w...

journal_title：Disease markers

authors： van Wijk DF,Stroes ES,Kastelein JJ

更新日期：2009-01-01 00:00:00

abstract：:Microtubule-associated protein 4 (MAP4) plays an important role in microtubule assembly and stabilization. The purpose of this study was to investigate the level of expression of MAP4 in lung adenocarcinoma (LADC) samples and to evaluate its prognostic value and the influence on cancer progression in LADC patients. Th...

journal_title：Disease markers

authors： Xia X,He C,Wu A,Zhou J,Wu J

更新日期：2018-03-18 00:00:00

abstract：:Cyclin-dependent kinase regulatory subunit 2 (CKS2) is a member of the cell cycle-dependent protein kinase subunit family, which is implicated as an oncogene in various malignancies. However, the clinical significance, oncogenic functions, and related mechanisms of CKS2 in hepatocellular carcinoma (HCC) remain largely...

journal_title：Disease markers

authors： Zhang J,Song Q,Liu J,Lu L,Xu Y,Zheng W

更新日期：2019-10-22 00:00:00

abstract：OBJECTIVE:Particularly interesting new cysteine-histidine rich protein (PINCH) is an important component of the local adhesion complexes and upregulated in several types of malignancies, and involved in the incidence and development of tumours. PINCH expression is also independently correlated with poorer survival in p...

journal_title：Disease markers

authors： Zhu ZL,Yan BY,Zhang Y,Yang YH,Wang ZM,Zhang HZ,Wang MW,Zhang XH,Sun XF

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND AIM:Because B-type natriuretic peptide is a powerful predictor of heart failure, its capability to predict a fatal outcome in stroke might be limited to the cardioembolic stroke subtype. In this study, we attempt to ascertain the difference in the prognostic value of N-terminal pro-B-type natriuretic pep...

journal_title：Disease markers

authors： Lee SJ,Lee DG,Lim DS,Hong S,Park JS

更新日期：2015-01-01 00:00:00

abstract：:The genetic variation at the Apolipoprotein E locus (APOE) is an important determinant of plasma lipids and has been implicated in various human pathological conditions. The objective of the present study was to estimate the distribution of APOE alleles in five Venezuelan communities: two Amerindian tribes (Bari and Y...

journal_title：Disease markers

authors： Fernández-Mestre MT,Yehirobi C,Montagnani S,Balbas O,Layrisse Z

更新日期：2005-01-01 00:00:00

abstract：AIM:In this study, we aimed to investigate the relationship between the histological fibrosis stage of nonalcoholic fatty liver disease (NAFLD) and serum connective tissue growth factor (CTGF) to determine the usefulness of this relationship in clinical practice. METHODS:Serum samples were collected from 51 patients w...

journal_title：Disease markers

authors： Colak Y,Senates E,Coskunpinar E,Oltulu YM,Zemheri E,Ozturk O,Doganay L,Mesci B,Yilmaz Y,Enc FY,Kiziltas S,Ulasoglu C,Tuncer I

更新日期：2012-01-01 00:00:00

abstract：:Immunological and immunogenetic investigations are described in a group of 28 women with a history of unexplained recurrent (greater than or equal to 3 consecutive) spontaneous abortions (RSA). Compared with female blood donor controls, recurrent aborters had significantly elevated mean serum complement C4 (p less tha...

journal_title：Disease markers

authors： Kilpatrick DC,Liston WA,Neill G,Maxwell C

更新日期：1989-04-01 00:00:00

abstract：:The role of human papillomavirus (HPV) in prostate carcinogenesis is highly controversial: some studies suggest a positive association between HPV infection and an increased risk of prostate cancer (PCa), whereas others do not reveal any correlation. In this study, we investigated the prognostic impact of HPV infectio...

journal_title：Disease markers

authors： Pascale M,Pracella D,Barbazza R,Marongiu B,Roggero E,Bonin S,Stanta G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:specific polymorphisms of genes regulating intracellular redox balance and oxidative stress are related to atherogenesis. Some studies have identified a relationship between progression of atherosclerosis and C242T mutation in CYBA gene coding for p22phox, a subunit of the NADH/NADPH oxidase system. DESIGN:...

journal_title：Disease markers

authors： Nasti S,Spallarossa P,Altieri P,Garibaldi S,Fabbi P,Polito L,Bacino L,Brunelli M,Brunelli C,Barsotti A,Ghigliotti G

更新日期：2006-01-01 00:00:00

abstract：:Cytoskeletal rearrangement occurs in variety of cellular processes and involves a wide spectrum of proteins. Gelsolin super family proteins control actin organization by severing and capping filament ends and nucleating actin assembly. Gelsolin is the founding member of this family and plays important role in pathogen...

journal_title：Disease markers

authors： Baig RM,Mahjabeen I,Sabir M,Masood N,Ali K,Malik FA,Kayani MA

更新日期：2013-01-01 00:00:00

abstract：:This study was undertaken to assess the biochemical changes induced in chronic schistosomiasis and/or chronic HCV, as well as to pinpoint the most significant parameters which could be used as dependable indices for the differentiation of single and coupled infections with or without liver cirrhosis. The selected pati...

journal_title：Disease markers

authors： Fahim FA,Esmat AY,Hassan GK,Abdel-Bary A

更新日期：2000-01-01 00:00:00

abstract：:Cardiovascular diseases are the main causes of mortality. Sudden cardiac death may also appear in athletes, due to underlying congenital or inherited cardiac abnormalities. The electrocardiogram is used in clinical practice and clinical trials, as a valid, reliable, accessible, inexpensive method. The aim of the prese...

journal_title：Disease markers

authors： Mozos I,Caraba A

更新日期：2015-01-01 00:00:00

abstract：:Lung disease due to non-tuberculous mycobacteria (NTM) is a poorly understood condition that is difficult to treat. Treatment remains problematic as few tools are available to help clinicians monitor disease progression or predict treatment outcome. In this study, plasma levels of several inflammatory molecules and th...

journal_title：Disease markers

authors： Lim A,Allison C,Tan DB,Oliver B,Price P,Waterer G

更新日期：2010-01-01 00:00:00

abstract：Background:Determination of neonate serum's N-acetyl-β-hexosaminidase (HEX) activity and correlation results with Apgar scale and factors routinely determined in newborn serum. Aims:Providing reference values of neonates serum HEX activities, and indicate their diagnostic significance. Study design:The study was perf...

journal_title：Disease markers

authors： Chojnowska S,Kamianowska M,Baran P,Zwierz K,Szczepański M

更新日期：2018-07-02 00:00:00

abstract：BACKGROUND:Stroke subtype diagnosis leads to specific therapies to reduce recurrences. Because nearly one third of patients remain with unknown etiology after a complete screening workup, we aim to investigate whether molecular markers of myocardial damage were associated with cardioembolic stroke and if they were usef...

journal_title：Disease markers

authors： Rodríguez-Yáñez M,Sobrino T,Blanco M,de la Ossa NP,Brea D,Rodríguez-González R,Leira R,Dávalos A,Castillo J

更新日期：2009-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/4703854.]. ...

journal_title：Disease markers

authors： Mutuiri SPM,Kutima HL,Mwapagha LM,Munyao JK,Kebira AN,Wanjiru I,Khamadi SA

更新日期：2017-01-01 00:00:00

abstract：:Kinesin family member 20A (KIF20A) has been recently reported to be upregulated and associated with increased invasiveness and metastasis in several malignancies. However, the role of KIF20A in colorectal cancer (CRC) is still unclear. This study is aimed at investigating the potential roles of KIF20A in the developme...

journal_title：Disease markers

authors： Zhang Q,Di J,Ji Z,Mi A,Li Q,Du X,Wang A,Wang A,Qin C

更新日期：2020-07-08 00:00:00

abstract：:Increasingly women at high risk of breast cancer are opting for prophylactic surgery to reduce their risks. Data from 10 European centres that offer a risk counselling and screening service to women at risk show different approaches to the option of preventive surgery, although most centres adhere to a protocol includ...

journal_title：Disease markers

authors： Evans DG,Anderson E,Lalloo F,Vasen H,Beckmann M,Eccles D,Hodgson S,Møller P,Chang-Claude J,Morrison P,Stoppa-Lyonnet D,Steel M,Haites N

更新日期：1999-10-01 00:00:00

abstract：:We first investigated the difference in microRNA expression between normal NP cells and degenerative NP cells using gene chip. We have found that the expression of ERK1/2 was decreased with overexpression of miR-155 in normal nucleus pulposus cell. Expression of ERK1/2 was increased with inhibition of miR-155. Overexp...

journal_title：Disease markers

authors： Ye D,Dai L,Yao Y,Qin S,Xie H,Wang W,Liang W

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:The clinical behavior of unicystic ameloblastoma varies according to its subtype. The assessment of its proliferative capacity, neovascularization, and invasiveness using relevant immunomarkers may aid in appropriate surgical therapeutic protocol. METHODS:18 cases of clinically and histologically confirmed uni...

journal_title：Disease markers

authors： Sah P,Menon A,Kamath A,Chandrashekar C,Carnelio S,Radhakrishnan R

更新日期：2013-01-01 00:00:00

abstract：:RFLP HLA-DRB1 analysis was performed on a total of 83 children born from HIV-infected mothers, 35 of whom were shown to be HIV-infected, while 48 reverted from seropositivity to seronegativity, indicating that they were not infected. Moreover, 89 healthy children were used as controls. It has been found that DRB1-14a ...

journal_title：Disease markers

authors： Greggio NA,Cameran M,Giaquinto C,Zacchello F,Koroliuk D,Colizzi V

更新日期：1993-06-01 00:00:00

abstract：Background:Obstructive sleep apnea (OSA) was highly prevalent in patients with type 2 diabetes (T2D). Cathepsin S (CTSS), a cysteine protease, is involved in the inflammatory activity in T2D and hypoxia conditions. The aim of the study was to evaluate whether CTSS could be involved in the inflammatory reaction of OSA i...

journal_title：Disease markers

authors： Wen W,Sun H,Yang Y,Jia Y,Fang F,Qin Y,Zhang M,Wei Y

更新日期：2020-09-25 00:00:00

abstract：BACKGROUND:The apolipoprotein (apo) B/apoA-I ratio represents the balance between apoB-rich atherogenic particles and apoA-I-rich antiatherogenic particles, and this ratio is considered to be a marker of cardiovascular risk. Although many studies have demonstrated the importance of the apoB/apoA-I ratio in predicting t...

journal_title：Disease markers

authors： Kaneva AM,Potolitsyna NN,Bojko ER,Odland JØ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Cystic fibrosis is a monogenic recessive disorder found predominantly in Caucasian population. This disease arises from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. In this study we consider poly T polymorphism c.1210-12T[5], c.1210-12T[7], c.1210-12T[9] (T{5}, T{7}, T{9}...

journal_title：Disease markers

authors： Tabaripour R,Niaki HA,Douki MR,Bazzaz JT,Larijani B,Yaghmaei P

更新日期：2012-01-01 00:00:00

abstract：:Cytoplasmic islet cell antibodies (ICA) were determined in a group of non-diabetic Caucasian schoolchildren (n = 4208). The prevalence rate for ICA positivity was 1.05 per cent (95 per cent confidence interval: 0.8-1.4 per cent). Analysis of HLA risk factors revealed that HLA-DRB1*03 (p less than 0.01), HLA-DRB1*04 (p...

journal_title：Disease markers

authors： Boehm BO,Seissler J,Glück M,Manfras BJ,Thomas H,Schmidt K,Rudert WA,Usadel KH,Trucco M,Scherbaum WA

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND/AIMS:The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). METHODS:98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies ...

journal_title：Disease markers

authors： Demarco AL,Rodrigues Mde L,Figueiredo JF,Deghaide NH,de Menezes MB,Demarco LA,Fernandes AP,Donadi EA

更新日期：2012-01-01 00:00:00

abstract：Background:We have previously shown that the deficiency of the gut enzyme intestinal alkaline phosphatase (IAP) is associated with type 2 diabetes mellitus (T2DM) in humans, and mice deficient in IAP develop the metabolic syndrome, a precipitant of T2DM and ischemic heart disease (IHD). We hypothesized that IAP deficie...

journal_title：Disease markers

authors： Malo J,Alam MJ,Shahnaz M,Kaliannan K,Chandra G,Aziz T,Sarker T,Bala M,Paul R,Saha CK,Karmakar PK,Malo MS

更新日期：2019-12-13 00:00:00

abstract：:Alterations of the retinoblastoma (Rb) gene have been described in several human neoplasms and recently, it has been suggested that these alterations may play a role in the development of endometrial carcinomas. Paraffin sections from 31 cases of normal endometrium (16 proliferative, 15 secretory), 35 hyperplastic les...

journal_title：Disease markers

authors： Ioachim EE,Goussia AC,Kitsiou EG,Charalabopoulos K,Mermiga E,Stefanaki S

更新日期：2002-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is a neurodegenerative disorder that accounts for nearly 70% of the more than 46 million dementia cases estimated worldwide. Although there is no cure for AD, early diagnosis and an accurate characterization of the disease progression can improve the quality of life of AD patients and their ca...

journal_title：Disease markers

authors： Cassani R,Estarellas M,San-Martin R,Fraga FJ,Falk TH

更新日期：2018-10-04 00:00:00