Genetic variability of Apolipoprotein E in different populations from Venezuela.

abstract：Objective:To systematically evaluate the significance of squamous cell carcinoma antigen (SCC-Ag) in the prognosis of cervical cancer. Methods:Literature from Pubmed, Embase, and Cochrane Library was retrieved to collect all English literature on the correlation between SCC-Ag and cervical cancer prognosis, and the qu...

journal_title：Disease markers

authors： Liu Z,Shi H

更新日期：2019-06-02 00:00:00

abstract：:In recent researches, high expression of nesfatin-1/nucleobindin-2 (NUCB2) is linked to poor prognosis in prostate and colon cancer due to the enhancement in proliferation, migration, and invasion. However, the role of nesfatin-1 in bladder cancer is not clear. In this study, we examined the expression of NUCB2 in bla...

journal_title：Disease markers

authors： Liu GM,Xu ZQ,Ma HS

更新日期：2018-09-19 00:00:00

abstract：Background:Few previous studies have comprehensively explored the level of DNA methylation and gene expression in ccRCC. The purpose of this study was to identify the key clear cell renal cell carcinoma- (ccRCC-) related DNA methylation-driven genes (MDG) and to build a prognostic model based on the level of DNA methyl...

journal_title：Disease markers

authors： Hu M,Xie J,Hou H,Liu M,Wang J

更新日期：2020-07-11 00:00:00

abstract：:Recent experiments have shown that when specific biomolecular interactions are confined to one surface of a microcantilever beam, changes in intermolecular nanomechanical forces provide sufficient differential torque to bend the cantilever beam. This has been used to detect single base pair mismatches during DNA hybri...

journal_title：Disease markers

authors： Majumdar A

更新日期：2002-01-01 00:00:00

abstract：:Cardiovascular diseases are the main causes of mortality. Sudden cardiac death may also appear in athletes, due to underlying congenital or inherited cardiac abnormalities. The electrocardiogram is used in clinical practice and clinical trials, as a valid, reliable, accessible, inexpensive method. The aim of the prese...

journal_title：Disease markers

authors： Mozos I,Caraba A

更新日期：2015-01-01 00:00:00

abstract：:HLA typing for antigens of the A, B, C, and DR loci was carried out on lymphocytes from a haemophilic (Type A) family which included four siblings with arthritis. No single haplotype was found to relate to the presence of haemophilia or haemophilic arthritis. ...

journal_title：Disease markers

authors： Steven MM,Sturrock RD,Forbes CD,Dick HM

更新日期：1986-10-01 00:00:00

abstract：:Deficiency alleles at the C4 loci within the MHC are associated with autoimmune diseases in Caucasoids and possibly other races. We therefore studied the relationship between relevant C4 alleles and other MHC markers in a random Thai/Chinese population. Over 90 per cent of C4AQO occurs within two supratypes (HLA Aw33,...

journal_title：Disease markers

authors： Kay PH,Grimsley G,Dawkins RL,Charoenwong P

更新日期：1987-03-01 00:00:00

abstract：:A growing interest in the usability of saliva has been observed recently. Using saliva as a diagnostic material is possible because it contains a varied range of composites, organic and inorganic like proteins, carbohydrates, and lipids, which are secreted into saliva. Moreover, this applies to drugs and their metabol...

journal_title：Disease markers

authors： Kułak-Bejda A,Waszkiewicz N,Bejda G,Zalewska A,Maciejczyk M

更新日期：2019-05-02 00:00:00

abstract：BACKGROUND:Lymph node (LN) metastasis was an independent risk factor for stomach cancer recurrence, and the presence of LN metastasis has great influence on the overall survival of stomach cancer patients. Thus, accurate prediction of the presence of lymph node metastasis can provide guarantee of credible prognosis eva...

journal_title：Disease markers

authors： Wu J,Xiao Y,Xia C,Yang F,Li H,Shao Z,Lin Z,Zhao X

更新日期：2017-01-01 00:00:00

abstract：:The eukaryotic initiation factor 3 (eIF3) is the largest and most complex translation initiation factor in mammalian cells. It consists of 13 subunits and among which several were implicated to have significant prognostic effects on multiple human cancer entities. To examine the expression profiles of eIF3 subunits an...

journal_title：Disease markers

authors： Wang D,Jia Y,Zheng W,Li C,Cui W

更新日期：2019-12-07 00:00:00

abstract：AIMS:To study the changes of the metabolic profile during the pathogenesis in monocrotaline (MCT) induced pulmonary arterial hypertension (PAH). METHODS:Forty male Sprague-Dawley (SD) rats were randomly divided into 5 groups (n = 8, each). PAH rats were induced by a single dose intraperitoneal injection of 60 mg/kg MC...

journal_title：Disease markers

authors： Lin T,Gu J,Huang C,Zheng S,Lin X,Xie L,Lin D

更新日期：2016-01-01 00:00:00

abstract：:Tumor-induced osteomalacia (TIO) is a rare acquired paraneoplastic disorder and fibroblast growth factor 23 (FGF23) plays a key role in its pathogenesis. This study was conducted to describe a novel FGF23 detecting procedure and describe clinical features of the disease. Fourteen TIO cases were retrieved and FGF23 exp...

journal_title：Disease markers

authors： Hu F,Jiang C,Zhang Q,Shi H,Wei L,Wang Y

更新日期：2016-01-01 00:00:00

abstract：:As the most common neoplasm arising from the kidney, renal cell carcinoma (RCC) continues to have a significant impact on global health. Conventional cross-sectional imaging has always served an important role in the staging of RCC. However, with recent advances in imaging techniques and postprocessing analysis, magne...

journal_title：Disease markers

authors： Wu Y,Kwon YS,Labib M,Foran DJ,Singer EA

更新日期：2015-01-01 00:00:00

abstract：:Increasingly women at high risk of breast cancer are opting for prophylactic surgery to reduce their risks. Data from 10 European centres that offer a risk counselling and screening service to women at risk show different approaches to the option of preventive surgery, although most centres adhere to a protocol includ...

journal_title：Disease markers

authors： Evans DG,Anderson E,Lalloo F,Vasen H,Beckmann M,Eccles D,Hodgson S,Møller P,Chang-Claude J,Morrison P,Stoppa-Lyonnet D,Steel M,Haites N

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND/AIMS:The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). METHODS:98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies ...

journal_title：Disease markers

authors： Demarco AL,Rodrigues Mde L,Figueiredo JF,Deghaide NH,de Menezes MB,Demarco LA,Fernandes AP,Donadi EA

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Microarray technology shows great potential but previous studies were limited by small number of samples in the colorectal cancer (CRC) research. The aims of this study are to investigate gene expression profile of CRCs by pooling cDNA microarrays using PAM, ANN, and decision trees (CART and C5.0). METHODS:...

journal_title：Disease markers

authors： Chu CM,Yao CT,Chang YT,Chou HL,Chou YC,Chen KH,Terng HJ,Huang CS,Lee CC,Su SL,Liu YC,Lin FG,Wetter T,Chang CW

更新日期：2014-01-01 00:00:00

abstract：Background:The ratio of early mitral inflow velocity to the global diastolic strain rate (E/E'sr) and global longitudinal systolic strain (GLS) of the left ventricle (LV) are emerging indices of diastolic and systolic functions, respectively, for the LV. Their prognostic significance in the prediction of mortality and ...

journal_title：Disease markers

authors： Huang JC,Su HM,Wu PY,Lee JJ,Lee WH,Chen SC,Chiu YW,Hsu YL,Chang JM,Chen HC

更新日期：2019-09-05 00:00:00

abstract：:Colorectal cancer is one of the most common cancers in the world. Due to its still undetermined pathogenesis, we are searching for signaling pathways that are important in the development of colorectal cancer. In this article, we present results of study on the role of ADAM proteins in colorectal cancer. The study inc...

journal_title：Disease markers

authors： Walkiewicz K,Strzelczyk J,Waniczek D,Biernacki K,Muc-Wierzgoń M,Copija A,Nowakowska-Zajdel E

更新日期：2019-09-02 00:00:00

abstract：:Decreased levels of brain-derived neurotrophic factor (BDNF) are assumed to play a crucial role in the pathophysiology of mild neurocognitive disorders (MNCDs). In this study, we compared plasma BDNF levels (at baseline and after two months of treatment with escitalopram) in patients with the main types of MNCDs and n...

journal_title：Disease markers

authors： Levada OA,Cherednichenko NV,Trailin AV,Troyan AS

更新日期：2016-01-01 00:00:00

abstract：:The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial infarction (AMI) does not decrease regardless of implementation of new technologies supporting opening culprit coronary artery and solving of ischemia-relating stenosis with primary percutaneous coronary intervention (PCI). Numerous...

journal_title：Disease markers

authors： Berezin AE,Berezin AA

更新日期：2020-06-12 00:00:00

abstract：Background:Cardiovascular disease (CVD) risks persist in patients despite the use of conventional treatments. This might be due to chronic inflammation as reflected in epidemiological studies associating circulating low-grade inflammatory markers with CVD recurrent events. Here, we explored this potential link by asses...

journal_title：Disease markers

authors： Khadir A,Kavalakatt S,Dehbi M,Alarouj M,Bennakhi A,Tiss A,Elkum N

更新日期：2018-12-13 00:00:00

abstract：UNLABELLED:The aim of this study was to investigate serum IL17 levels in patients with Crohn's disease (CD) and to investigate the relationship between serum IL17 levels with disease activity. METHODS:Fifty patients with CD and sex- and age-matched 40 healthy controls were included in the study. The serum IL17 levels,...

journal_title：Disease markers

authors： Sahin A,Calhan T,Cengiz M,Kahraman R,Aydin K,Ozdil K,Korachi M,Sokmen HM

更新日期：2014-01-01 00:00:00

abstract：:SIRT6 has been demonstrated to exert protective effects on endothelial cells and is closely associated with lipid metabolism, glucose metabolism, and obesity, indicating an important role in the pathogenesis and progression of coronary artery disease (CAD). Nonetheless, the biological significance of SIRT6 variants on...

journal_title：Disease markers

authors： Tang SS,Xu S,Cheng J,Cai MY,Chen L,Liang LL,Yang XL,Chen C,Liu XG,Xiong XD

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:To evaluate serum chemerin levels in patients with osteoporosis and healthy controls and to investigate the relationship between serum chemerin levels and bone mineral density (BMD). METHODS:An age- and gender-matched case-control study was conducted. Pearson's correlation test was performed to investigate ...

journal_title：Disease markers

authors： He J,Li JC,Xie H,Xu ZH,Sun YW,Shan Q

更新日期：2015-01-01 00:00:00

abstract：:A limited number of studies have been performed so far on the polymorphism in the transmembrane region (exon 5) of the major histocompatibility complex class I chain-related gene A (MICA) in patients with melanoma. However, the influence of MICA polymorphism in extracellular domains (exons 2, 3, and 4) has not been in...

journal_title：Disease markers

authors： Campillo JA,López-Hernández R,Martínez-Banaclocha H,Bolarín JM,Gimeno L,Mrowiec A,López M,Las Heras B,Minguela A,Moya-Quiles MR,Legáz I,Frías-Iniesta JF,García-Alonso AM,Álvarez-López MR,Martínez-Escribano JA,Muro M

更新日期：2015-01-01 00:00:00

abstract：:Prosthetic joint infection (PJI) is the most common cause of failure of total joint arthroplasty, but a gold standard for PJI diagnosis is still lacking. Advanced glycation end products (AGEs) are proinflammatory molecules inducing intracellular oxidative stress (OS) after binding to their cell membrane receptors (RAG...

journal_title：Disease markers

authors： Massaccesi L,Bonomelli B,Marazzi MG,Drago L,Romanelli MMC,Erba D,Papini N,Barassi A,Goi G,Galliera E

更新日期：2017-01-01 00:00:00

abstract：:Physical activity as a part of the lifestyle is a significant factor influencing health condition. Exercises that require stamina are of particular importance. Oxygen metabolism, which is a significant part of all longer training processes, has an influence on cardiovascular and respiratory system functioning as well ...

journal_title：Disease markers

authors： Mieczkowska J,Rutkowska E,Mosiewicz J,Mosiewicz B

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Both adaptive and innate immune systems are involved in coronary artery disease (CAD). The aim of this study was to evaluate TH17 cytokines expression profiles in un-stimulated peripheral blood lymphocytes (PBMCs) of patients with coronary artery disease. METHODS:Expression profiles of IL-17, IL-23, and TGF-...

journal_title：Disease markers

authors： Khojasteh-Fard M,Abolhalaj M,Amiri P,Zaki M,Taheri Z,Qorbani M,Bazzaz JT,Amoli MM

更新日期：2012-01-01 00:00:00

abstract：:Pancreatic adenocarcinoma (PDAC) still represents a devastating disease associated with a very limited survival. Novel biomarkers allowing an early diagnosis as well as an optimal selection of suitable treatment options for individual patients are urgently needed to improve the dismal outcome of PDAC patients. Recentl...

journal_title：Disease markers

authors： Loosen SH,Luedde M,Lurje G,Spehlmann M,Paffenholz P,Ulmer TF,Tacke F,Vucur M,Trautwein C,Neumann UP,Luedde T,Roderburg C

更新日期：2019-10-20 00:00:00

abstract：INTRODUCTION:Acute gangrenous appendicitis (AGA) is a common medical condition; however, the grade of appendicitis usually cannot be established preoperatively. We have attempted to identify some indicators, such as the mean platelet volume (MPV) and the platelet distribution width (PDW), to diagnose AGA. Aims. To eval...

journal_title：Disease markers

authors： Fan Z,Pan J,Zhang Y,Wang Z,Zhu M,Yang B,Shi L,Jing H

更新日期：2015-01-01 00:00:00