Abstract:
BACKGROUND/AIMS:The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). METHODS:98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies and without TCR) were studied. RESULTS:The HLA-B35 was significantly increased in TRC group (p=0.0038). CONCLUSION:The presence of HLA-B35 may simultaneously predispose to progression to AIDS and TRC.
journal_name
Dis Markersjournal_title
Disease markersauthors
Demarco AL,Rodrigues Mde L,Figueiredo JF,Deghaide NH,de Menezes MB,Demarco LA,Fernandes AP,Donadi EAdoi
10.3233/DMA-2012-00935subject
Has Abstractpub_date
2012-01-01 00:00:00pages
309-12issue
6eissn
0278-0240issn
1875-8630pii
P98878521V653865journal_volume
33pub_type
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