Intestinal Alkaline Phosphatase Deficiency Is Associated with Ischemic Heart Disease.

abstract：:Physical activity as a part of the lifestyle is a significant factor influencing health condition. Exercises that require stamina are of particular importance. Oxygen metabolism, which is a significant part of all longer training processes, has an influence on cardiovascular and respiratory system functioning as well ...

journal_title：Disease markers

authors： Mieczkowska J,Rutkowska E,Mosiewicz J,Mosiewicz B

更新日期：2016-01-01 00:00:00

abstract：:Because tandem mass spectrometry- (MS/MS-) based newborn screening identifies many suspicious cases of fatty acid oxidation and carnitine cycle disorders, a simple, noninvasive test is required to confirm the diagnosis. We have developed a novel method to evaluate the metabolic defects in peripheral blood mononuclear ...

journal_title：Disease markers

authors： Yuasa M,Hata I,Sugihara K,Isozaki Y,Ohshima Y,Hara K,Tajima G,Shigematsu Y

更新日期：2019-02-07 00:00:00

abstract：:Increasingly women at high risk of breast cancer are opting for prophylactic surgery to reduce their risks. Data from 10 European centres that offer a risk counselling and screening service to women at risk show different approaches to the option of preventive surgery, although most centres adhere to a protocol includ...

journal_title：Disease markers

authors： Evans DG,Anderson E,Lalloo F,Vasen H,Beckmann M,Eccles D,Hodgson S,Møller P,Chang-Claude J,Morrison P,Stoppa-Lyonnet D,Steel M,Haites N

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Tissue Polypeptide Specific antigen has recently been proposed as diagnostic marker of apoptosis in NonAlcoholic SteatoHepatitis. The aim of this study was to validate in patients suffering from NonAlcoholic SteatoHepatitis the clinical utility of this marker after different programs of weight reduction. ME...

journal_title：Disease markers

authors： Tarantino G,Mazzarella C,Tarantino M,Di Minno MN,Conca P

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:During progression of gastric cancer (GC), degradation of the extracellular matrix is mediated by the matrix metalloproteases (MMPs) and their tissue inhibitors (TIMPs): changes in the expression of these have been related to unfavorable prognosis in GC. OBJECTIVE:To analyze the expression of certain MMPs a...

journal_title：Disease markers

authors： de la Peña S,Sampieri CL,Ochoa-Lara M,León-Córdoba K,Remes-Troche JM

更新日期：2014-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide due to latent liver disease, late diagnosis, and nonresponse to systemic treatments. Till now, surgical and/or biopsy specimens are still generally used as a gold standard by the clinicians for clinical decision-making. Howeve...

journal_title：Disease markers

authors： Yin CQ,Yuan CH,Qu Z,Guan Q,Chen H,Wang FB

更新日期：2016-01-01 00:00:00

abstract：:We evaluated the occurrence of mutations in P53, K-RAS, COX-2, expression of COX-2 and hTERT and relations among clinicopathological signs. P53 mutations were identified in 34.4% of tumours, the majority of them occurring in SCC (squamous cell carcinoma, 55.6%). K-RAS was mutated in 12.2% of NSCLC tumours, the majorit...

journal_title：Disease markers

authors： Strazisar M,Rott T,Glavac D

更新日期：2008-01-01 00:00:00

abstract：Aim:To evaluate the diagnosis value of serum human epididymis protein 4 (HE4), cancer antigen 125 (CA125), the Risk of Ovarian Malignancy Algorithm (ROMA), and Copenhagen Index (CPH-I) at early stages for differentiating borderline ovarian tumors from epithelial ovarian cancer. Methods:We recruited 144 borderline ovar...

journal_title：Disease markers

authors： Wang Z,Tao X,Ying C

更新日期：2019-10-13 00:00:00

abstract：Background:Epithelial ovarian cancer (EOC) is highly lethal worldwide. Factors involved in the inflammation and hormone-associated signaling pathway play vital roles in EOC carcinogenesis. The transforming growth factor-β- (TGF-β-) activated kinase 1 (MAP3K7) binding protein 2 (TAB2), mediating convergence of inflammat...

journal_title：Disease markers

authors： Huang X,Shen C,Zhang Y,Li Q,Li K,Wang Y,Song Y,Su M,Zhou B,Wang W

更新日期：2019-08-14 00:00:00

abstract：:The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial infarction (AMI) does not decrease regardless of implementation of new technologies supporting opening culprit coronary artery and solving of ischemia-relating stenosis with primary percutaneous coronary intervention (PCI). Numerous...

journal_title：Disease markers

authors： Berezin AE,Berezin AA

更新日期：2020-06-12 00:00:00

abstract：AIM:This study was conducted to find out the optimal vitamin D cutoff point in predicting activity of RA disease. MATERIALS AND METHODS:One hundred and two rheumatoid arthritis Saudi patients of both genders were recruited in this study. Vitamin D as 25-hydroxy-vitamin D [25(OH)D] was measured and serum level less tha...

journal_title：Disease markers

authors： Azzeh FS,Kensara OA

更新日期：2015-01-01 00:00:00

abstract：Background:Breast cancer is the commonest malignancy in women worldwide. It is estimated to affect approximately 1.5 million women annually and responsible for the greatest number of cancer-related mortalities among women. In 2018, breast cancer mortalities stood at 627,000 women representing approximately 15% of all c...

journal_title：Disease markers

authors： Arko-Boham B,Owusu BA,Aryee NA,Blay RM,Owusu EDA,Tagoe EA,Adams AR,Gyasi RK,Adu-Aryee NA,Mahmood S

更新日期：2020-05-24 00:00:00

abstract：Background:The role of the NFKB1 gene rs28362491 polymorphism and NFKBIA gene rs2233406 polymorphism in the development of head and neck cancer (HNC) remains controversial. This meta-analysis was performed to assess the relationship between the gene polymorphisms and HNC quantitatively. Methods:PubMed, Embase, Web of ...

journal_title：Disease markers

authors： Li L,Zhang ZT

更新日期：2019-09-12 00:00:00

abstract：:Clinical variables contribute to the severity of Kashin-Beck disease (KBD). However, it is unclear if there is a correlation between gene expression and clinical variables. Peripheral blood samples were collected from 100 patients with KBD and 100 healthy controls from KBD-endemic areas to identify differentially expr...

journal_title：Disease markers

authors： Wang X,Ning Y,Zhang P,Yang L,Li C,Zhou R,Guo X

更新日期：2019-01-03 00:00:00

abstract：Aims:The impact of MMP-1 (-519A/G, -1607 1G/2G), MMP-3 Lys45Glu (A/G), MMP-7 -181A/G, and MMP-12 -82A/G variants and plasma MMP levels on obesity and microvascular reactivity in Tunisians. Methods:Our population included 202 nonobese and 168 obese subjects. Anthropometric, biochemical, and microvascular parameters wer...

journal_title：Disease markers

authors： Boumiza S,Bchir S,Ben Nasr H,Abbassi A,Jacob MP,Norel X,Tabka Z,Chahed K

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:A possible association between the TACC3 rs798766 polymorphism and urinary bladder cancer risk has been indicated in published literature. We performed this meta-analysis as a synthesis of all relevant data to summarize currently available evidence and to provide estimation with increased precision. METHODS...

journal_title：Disease markers

authors： Meng XY,Shi MJ,Chen JF,Liao Y,Hu BW,Hireche A

更新日期：2017-01-01 00:00:00

abstract：Purpose:To determine the frequency of the genotype of signal transducer and activator of transcription protein 3 (STAT3) rs744166, sirtuin (SIRT1) rs12778366, fibroblast growth factor (FGFR2) rs2981582, and advanced glycosylation end product-specific receptor (RAGE) rs1800625 gene polymorphisms in patients with larynge...

journal_title：Disease markers

authors： Uloza V,Tamauskaite T,Vilkeviciute A,Pasvenskaite A,Liutkevicius V,Liutkeviciene R

更新日期：2019-11-12 00:00:00

abstract：:Antibodies against myelin oligodendrocyte antigens have been found in the immunoreactive brain lesions of Multiple Sclerosis (MS) patients. Recently it has been proposed that these antibodies can be used as a prognostic marker in the course of disease. However, the serum levels of these autoantibodies during different...

journal_title：Disease markers

authors： Angelucci F,Mirabella M,Frisullo G,Caggiula M,Tonali PA,Batocchi AP

更新日期：2005-01-01 00:00:00

abstract：AIMS:To study the changes of the metabolic profile during the pathogenesis in monocrotaline (MCT) induced pulmonary arterial hypertension (PAH). METHODS:Forty male Sprague-Dawley (SD) rats were randomly divided into 5 groups (n = 8, each). PAH rats were induced by a single dose intraperitoneal injection of 60 mg/kg MC...

journal_title：Disease markers

authors： Lin T,Gu J,Huang C,Zheng S,Lin X,Xie L,Lin D

更新日期：2016-01-01 00:00:00

abstract：Background:Obese women with gestational diabetes mellitus (GDM) have a higher risk of adverse outcomes than women with obesity or GDM alone. Our study is aimed at investigating the discriminatory power of circulatory Wnt1-inducible signaling pathway protein-1 (WISP1), a novel adipocytokine, on the copresence of prepreg...

journal_title：Disease markers

authors： Liu L,Hu J,Yang L,Wang N,Liu Y,Wei X,Gao M,Wang Y,Ma Y,Wen D

更新日期：2020-04-14 00:00:00

abstract：:In recent researches, high expression of nesfatin-1/nucleobindin-2 (NUCB2) is linked to poor prognosis in prostate and colon cancer due to the enhancement in proliferation, migration, and invasion. However, the role of nesfatin-1 in bladder cancer is not clear. In this study, we examined the expression of NUCB2 in bla...

journal_title：Disease markers

authors： Liu GM,Xu ZQ,Ma HS

更新日期：2018-09-19 00:00:00

abstract：:The surface and cytoplasmic expression of CD1a molecules was analysed by indirect immunofluorescence (IIF) and dot blot assay (DBA) in a panel of 40 acute and chronic leukaemias. Thirty-two per cent of the samples were positive by IIF but, surprisingly, 72 per cent of the patients were positive by DBA, suggesting the ...

journal_title：Disease markers

authors： Salamone MC,Roisman FR,Morelli AE,Noli MI,Fainboim L

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:To evaluate serum chemerin levels in patients with osteoporosis and healthy controls and to investigate the relationship between serum chemerin levels and bone mineral density (BMD). METHODS:An age- and gender-matched case-control study was conducted. Pearson's correlation test was performed to investigate ...

journal_title：Disease markers

authors： He J,Li JC,Xie H,Xu ZH,Sun YW,Shan Q

更新日期：2015-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/4703854.]. ...

journal_title：Disease markers

authors： Mutuiri SPM,Kutima HL,Mwapagha LM,Munyao JK,Kebira AN,Wanjiru I,Khamadi SA

更新日期：2017-01-01 00:00:00

abstract：:A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and progression to AIDS, which is highly variable among individuals and populations. This review focuses on the chemokine-receptor and chemokine genes, which were extensively studied because of their role as HIV co-receptor o...

journal_title：Disease markers

authors： Chatterjee A,Rathore A,Vidyant S,Kakkar K,Dhole TN

更新日期：2012-01-01 00:00:00

abstract：:Malignant mesothelioma (MM) is an aggressive malignancy of the serosal membranes. Early diagnosis and accurate prognostication remain problematic. BAP1 is a tumour suppressor gene commonly mutated in MM. Germline BAP1 mutation has been associated with early onset and less aggressive disease compared with sporadic MM. ...

journal_title：Disease markers

authors： Pulford E,Huilgol K,Moffat D,Henderson DW,Klebe S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Stroke subtype diagnosis leads to specific therapies to reduce recurrences. Because nearly one third of patients remain with unknown etiology after a complete screening workup, we aim to investigate whether molecular markers of myocardial damage were associated with cardioembolic stroke and if they were usef...

journal_title：Disease markers

authors： Rodríguez-Yáñez M,Sobrino T,Blanco M,de la Ossa NP,Brea D,Rodríguez-González R,Leira R,Dávalos A,Castillo J

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Left ventricular dysfunction (LVD), followed by fall in cardiac output is one of the major complications in some coronary artery disease (CAD) patients. The decreased cardiac output over time leads to activation of the renin-angiotensin-aldosterone system which results in vasoconstriction by influencing salt...

journal_title：Disease markers

authors： Mishra A,Srivastava A,Mittal T,Garg N,Mittal B

更新日期：2012-01-01 00:00:00

abstract：AIM:The purpose of this study is to determine the association between eotaxin 426 C/T, -384 A/G, 67 G/A, eNOS -786 T/C, 4 a/b, and MMP-13 rs640198 G/T and prognosis of patients with known CAD. METHODS:From total of 1161 patients referred to coronary angiography, 532 patients with angiographically confirmed CAD were se...

journal_title：Disease markers

authors： Kincl V,Máchal J,Drozdová A,Panovský R,Vašků A

更新日期：2015-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/2138627.]. ...

journal_title：Disease markers

authors： Marrugal Á,Ojeda L,Paz-Ares L,Molina-Pinelo S,Ferrer I

更新日期：2018-07-08 00:00:00