Abstract:
:The basal caeliferan family Tetrigidae is investigated to identify neuropeptides belonging to the adipokinetic hormone (AKH) family. The pygmy grasshopper Tetrix subulata contains in its corpus cardiacum two octapeptides as revealed by liquid chromatography coupled to electrospray ionization mass spectrometry. The less abundant peptide is the well-known Schgr-AKH-II (pELNFSTGW amide) which is suggested to be the ancestral AKH of Caelifera and Ensifera. The second peptide, Tetsu-AKH (pEFNFTPGW amide), is novel and quite unusual with its third aromatic residue at position 2. It is thought to be autapomorphic for Caelifera. Tetsu-AKH has hyperlipemic activity in T. subulata and in Schistocerca gregaria.
journal_name
Peptidesjournal_title
Peptidesauthors
Gäde G,Šimek P,Marco HGdoi
10.1016/j.peptides.2015.01.008subject
Has Abstractpub_date
2015-06-01 00:00:00pages
43-9eissn
0196-9781issn
1873-5169pii
S0196-9781(15)00033-9journal_volume
68pub_type
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