New roles of the multidimensional adipokine: chemerin.

abstract：:Members of the neprilysin family of neutral endopeptidases (M13) are typically membrane-bound enzymes known to be involved in the extra-cellular metabolism of signalling peptides and have important roles during mammalian embryogenesis. In this study we show that membranes prepared from embryos of Drosophila melanogast...

journal_title：Peptides

authors： Bland ND,Thomas JE,Audsley N,Shirras AD,Turner AJ,Isaac RE

更新日期：2007-01-01 00:00:00

abstract：:A peptide designated cicerarin, with an N-terminal amino acid sequence VKSTGRADDDLAVKTKYLPP dissimilar from known proteins and peptides and a molecular mass of 8kDa, was isolated from seeds of the green chickpea Cicer arietinum cv green chickpea. Cicerarin was isolated with a procedure that involved ion exchange chrom...

journal_title：Peptides

authors： Chu KT,Liu KH,Ng TB

更新日期：2003-05-01 00:00:00

abstract：:In lieu of H-Dmt-Tic-OH, H-Dmt-analogues included 2-amino-3(1H-benzoimidazol-2-yl)-propionic acid, N(Bzl)Gly, L-octahydroindole-2-carboxylic acid, [3S-(3alpha,4abeta, 8abeta)]-decahydro-3-isoquinoline carboxylic acid, benzimidazole-, pyridoindole- or spiroinden-derivatives, or C-terminally modified. L- or D-Ala, Sar, ...

journal_title：Peptides

authors： Balboni G,Salvadori S,Guerrini R,Bianchi C,Santagada V,Calliendo G,Bryant SD,Lazarus LH

更新日期：2000-11-01 00:00:00

abstract：:An immunohistochemical mapping study in the brain and upper spinal cord of the turtle Testudo hermanni Gmelin revealed a wide distribution of somatostatin perikarya and fibres. Within the telencephalon, somatostatin perikarya are present in the anterior olfactory nucleus, in the medial, dorsomedial and dorsal cortex, ...

journal_title：Peptides

authors： Weindl A,Triepel J,Kuchling G

更新日期：1984-01-01 00:00:00

abstract：:Peptides of the adipokinetic hormone (AKH)/red pigment-concentrating hormone (RPCH) family were isolated and sequenced from the retrocerebral corpora cardiaca of four kissing bugs which are all vectors of the protozoan Trypanosoma cruzi responsible for Chagas' disease. The sequence of three novel AKHs were deduced fro...

journal_title：Peptides

authors： Marco HG,Simek P,Clark KD,Gäde G

更新日期：2013-03-01 00:00:00

abstract：:The in vivo effects of JMV-320 (a highly selective CCKB receptor ligand) and of CCK-4 on exploratory activity and memory in rats were compared. JMV-320 and CCK-4 did not modulate exploratory activity in an open field test but decreased it in an elevated plus-maze. CCK-4 (50 micrograms/kg) impaired passive avoidance re...

journal_title：Peptides

authors： Hadjiivanova C,Kehayov R,Petkov VV,Amblard M,Martinez J

更新日期：1995-01-01 00:00:00

abstract：:Neuropeptide S (NPS) produces several biological actions by activating a formerly orphan GPCR, now named NPS receptor (NPSR). It has been previously demonstrated that NPS stimulates murine leukocyte chemotaxis in vitro. In the present study we investigated the ability of NPS, in comparison with the proinflammatory pep...

journal_title：Peptides

authors： Filaferro M,Novi C,Ruggieri V,Genedani S,Alboni S,Malagoli D,Caló G,Guerrini R,Vitale G

更新日期：2013-01-01 00:00:00

abstract：:The aim of the present study was to investigate how suckling influences the plasma levels of oxytocin and vasoactive intestinal peptide in lactating dogs. Blood-samples were drawn from ten lactating beagles during suckling, in week one and week three of the five week long lactation period and the levels of vasoactive ...

journal_title：Peptides

authors： Eriksson M,Lindén A,Stock S,Uvnäs-Moberg K

更新日期：1987-05-01 00:00:00

abstract：:We assessed the plasma acyl ghrelin (AG), unacyl ghrelin (UAG), and total ghrelin (TGhr) levels in Chinese adults with pre-diabetes and newly diagnosed diabetes mellitus (NDDM) after an oral glucose tolerance test (OGTT), and abdominal subcutaneous fat area and visceral fat area (VFA) were measured. Fasting AG level w...

journal_title：Peptides

authors： Huang L,Tong Y,Zhang F,Yang Q,Li D,Xie S,Li Y,Cao H,Tang L,Zhang X,Tong N

更新日期：2014-10-01 00:00:00

abstract：:In this study, antimicrobial peptide S-thanatin (Ts) was chemically synthesized and linked to keyhole limpet hemocyanin (KLH) and bovine serum albumin (BSA) by carbodiimide reagent. Rabbits were immunized with Ts-KLH and polyclonal antibody against Ts was purified by fractional precipitation of ammonium sulfate, coupl...

journal_title：Peptides

authors： Wu G,Wang S,Wang X,Li X,Deng X,Shen Z,Xi T

更新日期：2011-07-01 00:00:00

abstract：:The binding of monoiodo 125I-Trp11-neurotensin to purified rat gastric fundus smooth muscle plasma membranes was characterized. Specific binding of ligand in subcellular fractions from rat fundus smooth muscle showed a distribution that paralleled that of several plasma membrane marker enzymes. 125I-Trp11-neurotensin ...

journal_title：Peptides

authors： Kitabgi P,Kwan CY,Fox JE,Vincent JP

更新日期：1984-09-01 00:00:00

abstract：:Beta-amyloid (Aβ) peptides are secreted from neurons, resulting in extracellular accumulation of Aβ and neurodegeneration of Alzheimer's disease. Because neuronal secretion is fundamental for the release of neurotransmitters, this study assessed the hypothesis that Aβ undergoes co-release with neurotransmitters. Model...

journal_title：Peptides

authors： Toneff T,Funkelstein L,Mosier C,Abagyan A,Ziegler M,Hook V

更新日期：2013-08-01 00:00:00

abstract：:alpha-MSH immunoreactive peptides were fractionated and characterized in rat and human brain and rat pituitary by reversed phase high pressure liquid chromatographic techniques. alpha-MSH and deacetylated alpha-MSH were two major naturally existing peptides in both brain and pituitary gland. Subsequent experiments exa...

journal_title：Peptides

authors： O'Donohue TL,Handelmann GE,Chaconas T,Miller RL,Jacobowitz DM

更新日期：1981-10-01 00:00:00

abstract：:The renin-angiotensin system (RAS) is now recognized as an important modulator of body metabolic processes. The discovery of angiotensin-converting enzyme 2 (ACE2) has renewed interest in the potential therapeutic role of RAS modulation. Recent studies have pointed out the importance of the local balance between ACE/A...

journal_title：Peptides

authors： Moreira de Macêdo S,Guimarães TA,Feltenberger JD,Sousa Santos SH

更新日期：2014-12-01 00:00:00

abstract：:The RPCH and beta-actin cDNAs from the crayfish Cherax quadricarinatus were amplified, cloned and sequenced. The primary structure sequences of these cDNAs were compared to other members of the AKH/RPCH family. Fluctuations in the amount of the C. quadricarinatus RPCH and beta-actin mRNAs, as cDNAs, were quantified ev...

journal_title：Peptides

authors： Martínez-Pérez F,Zinker S,Aguilar G,Valdés J,Aréchiga H

更新日期：2005-12-01 00:00:00

abstract：:As the frequent emergence of the resistant bacteria, the development of new agents with a new action mode attracts a great deal of interest. It is now widely accepted that antimicrobial peptides (AMPs) are promising alternatives to conventional antibiotics. In this study, antimicrobial peptide polybia-MPI and its anal...

journal_title：Peptides

authors： Wang K,Yan J,Dang W,Liu X,Chen R,Zhang J,Zhang B,Zhang W,Kai M,Yan W,Yang Z,Xie J,Wang R

更新日期：2013-01-01 00:00:00

abstract：:There is growing evidence of the antimicrobial properties of histones and histone-derived peptides; however, most of them are specific to lysine (Lys)-rich histones (H1, H2A, and H2B). In the present study, we focused on arginine (Arg)-rich histones (H3 and H4) and investigated their antimicrobial properties in compar...

journal_title：Peptides

authors： Tagai C,Morita S,Shiraishi T,Miyaji K,Iwamuro S

更新日期：2011-10-01 00:00:00

abstract：:Cocaine- and amphetamine-regulated transcript (CART) is a neurotransmitter and hormone, involved in the regulation of e.g. food intake, body weight, reward and addiction, and stress response. CART has also been found to affect insulin secretion and beta cell morphology, both in vivo and in vitro. Furthermore, CART aff...

journal_title：Peptides

authors： Drott CJ,Norman D,Espes D

更新日期：2021-01-01 00:00:00

abstract：:We evaluated behavior and cognitive performance in a line of transgenic mice that overexpress the rat gene for vasopressin. Open field testing revealed greatest habituation in homozygous mice. Passive avoidance performance indicated equal learning and memory ability of transgenic compared to normal mice. Drinking beha...

journal_title：Peptides

authors： Miller M,Haroutunian V,Wiltshire-Clement M

更新日期：1995-01-01 00:00:00

abstract：:Thyroglobulin (Tg) is cleaved into several peptides during thyroid hormone synthesis, an oxidative process. P40, an iodinated C-terminal peptide from human Tg, has a molecular weight of about 40 kDa and contains two hormonogenic sites. P40 is the smallest peptide that is still recognized by monoclonal antibodies from ...

journal_title：Peptides

authors： El Hassani RA,Estienne V,Blanchin S,Durand-Gorde JM,Mallet B,De Micco C,Carayon P,Lalaoui K,Ruf J

更新日期：2004-06-01 00:00:00

abstract：:This is the first report on the structural identity of a neuropeptide of the insect order Megaloptera. A peptide was isolated and sequenced from the retrocerebral corpora cardiaca glands of the alderfly, Sialis lutaria. The sequence of the peptide was deduced from the multiple MS(N) electrospray mass data as that of a...

journal_title：Peptides

authors： Gäde G,Simek P,Marco HG

更新日期：2009-03-01 00:00:00

abstract：:Diadenosine polyphosphates (APnAs) are endogenous compounds and exert diverse cardiovascular functions. However, the effects of APnAs on atrial ANP release and contractility have not been studied. In this study, the effects of diadenosine tetraphosphate (AP4A) on atrial ANP release and contractility, and their mechani...

journal_title：Peptides

authors： Yuan K,Cao C,Bai GY,Kim SZ,Kim SH

更新日期：2007-07-01 00:00:00

abstract：:In vitro pepsin treatment of plasma proteins generates biologically active peptides such as enkephalin-related peptides. These peptides were characterized using chromatographic techniques along with a radioimmunoassay procedure involving the use of Leu-enkephalin and Met-enkephalin antisera. Serum albumin is the only ...

journal_title：Peptides

authors： Garreau I,Pejoan C,Bressollier P,Verneuil B,Cucumel K,Cupo A

更新日期：1994-01-01 00:00:00

abstract：:C-type natriuretic peptide (CNP) was recently found in the myocardium, but possible insights into differences between atrium and ventricle production are so far lacking. Our aim was to evaluate, in an experimental model of pacing-induced heart failure (HF), plasma and tissue levels of CNP and mRNA expression of the pe...

journal_title：Peptides

authors： Del Ry S,Cabiati M,Lionetti V,Emdin M,Recchia FA,Giannessi D

更新日期：2008-12-01 00:00:00

abstract：:Urotensin II (UII), which was originally isolated from the teleost urophysis, was identified as an endogenous ligand for orphan G protein-coupled receptor 14 (GPR14). The structure of mammalian UII was confirmed by isolation from spinal cord in porcine, or was easily predicted from the sequence of prepro-UII in human....

journal_title：Peptides

authors： Sugo T,Mori M

更新日期：2008-05-01 00:00:00

abstract：:The effect of naturally occurring cannabinoids, delta 9-tetrahydrocannabinol (THC), cannabinol (CBN) and cannabidiol (CBD), on the brain receptors for thyrotropin releasing hormone (TRH) was investigated. TRH receptors were labeled with 3H-(3-MeHis2)TRH (3H-MeTRH). 3H-MeTRH bound specifically to rat brain membranes at...

journal_title：Peptides

authors： Bhargava HN,Gulati A

更新日期：1988-07-01 00:00:00

abstract：:The distribution of the VIP containing structures was studied in the gut and in the paravertebral sympathetic ganglia of the quail and chick embryos by immunocytochemistry. In the gut, development of peptidergic nerves followed a craniocaudal gradient. Immunoreactive fibres were first visible in the oesophagus at day ...

journal_title：Peptides

authors： Fontaine-Perus J

更新日期：1984-03-01 00:00:00

abstract：:In an attempt to establish the role of F8Famide in opioid activity modulation, we examined the effects of intracerebroventricular administration of the F8Famide analogs (1DME)Y8Fa and (3D)Y8Fa on intestinal transit in mice. (1DME)Y8Fa (0.88 to 22 nmol) inhibited intestinal transit as did F8Famide and morphine. An IP i...

journal_title：Peptides

authors： Gicquel S,Fioramonti J,Bueno L,Zajac JM

更新日期：1993-07-01 00:00:00

abstract：:A study was made of the effect of adrenalectomy over different periods of time (6, 15 and 21 days) on exocrine pancreatic secretion in the rat in basal conditions and under stimulation with CCK. It was observed that adrenalectomy does not alter the rate of pancreatic flow but the response capacity to CCK is depressed....

journal_title：Peptides

authors： Manso MA,De Dios I,Garcia AM,Calvo JJ

更新日期：1988-05-01 00:00:00

abstract：:Receptor binding analysis was performed in the renal medulla from 2-month-old rats, an extrapituitary tissue containing the highest level of GHRH receptor mRNA. At 4 degrees C, in the presence of a cocktail of protease inhibitors, binding of [125I-Tyr(10)]hGHRH (1-44)NH(2) to medullary homogenates was specific, time-d...

journal_title：Peptides

authors： Boulanger L,Girard N,Strecko J,Gaudreau P

更新日期：2002-06-01 00:00:00