Abstract：
:The distribution of the VIP containing structures was studied in the gut and in the paravertebral sympathetic ganglia of the quail and chick embryos by immunocytochemistry. In the gut, development of peptidergic nerves followed a craniocaudal gradient. Immunoreactive fibres were first visible in the oesophagus at day 9 in the quail and day 10 in the chick, at 12 days they extended over the whole length of the gut. Cell bodies were localized at day 9 in the foregut and observed in the mid- and hind-gut just before hatching. Transplantations on the chorioallantoic membrane of fragments of various parts of the digestive tract clearly demonstrated that VIP nerve cell bodies belonged to the intrinsic innervation of the gut. Besides the gut, sympathetic paravertebral ganglia contained cells with VIP immunoreactivity detected at day 9 and 10 in quail and chick respectively. In order to find out whether VIP containing neurons differentiated normally in chick embryos in which quail neural crest cells had been implanted at an early stage of development we looked for the appearance of peptidergic neurones in the following situations: when the quail neural primordium had been grafted orthotopically and isochronically into chick host (1) at the adrenomedullary (somites 18-24) and (2) at the vagal (somites 1-7) levels of the neural axis. In all conditions VIP immunoreactivity was observed in quail cells located either in the sympathetic paravertebral ganglia of the trunk at the level of the graft or in the enteric ganglia according to the graft was made at the adrenomedullary and vagal levels respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Peptidesjournal_title
Peptidesauthors
Fontaine-Perus Jdoi
10.1016/0196-9781(84)90206-7subject
Has Abstractpub_date
1984-03-01 00:00:00pages
195-200issue
2eissn
0196-9781issn
1873-5169pii
0196-9781(84)90206-7journal_volume
5pub_type
杂志文章相关文献
PEPTIDES文献大全abstract：:Discovering the informational rule(s) underlying structure-function relationships in the protein language is at the core of biology. Current theories have proven inadequate to explain the origins of biological information such as that found in nucleotide and amino acid sequences. Here, we demonstrate that the informat...
journal_title：Peptides
pub_type： 杂志文章,评审
doi：10.1016/j.peptides.2010.02.003
更新日期：2010-05-01 00:00:00
abstract：:The Manduca allatotropin (Mas-AT) gene is expressed as at least three mRNA isoforms that differ from each other by alternative splicing. The location at which the alternative exons are included in the mature mRNAs occur within the open reading frame, so that three different propeptides are predicted as translation pro...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(00)00378-8
更新日期：2001-02-01 00:00:00
abstract：:More than 40 peptides belonging to the -Y/FXFGL-NH(2) allatostatin superfamily have been isolated and identified from the central nervous system (CNS) of the tiger prawn, Penaeus monodon (Crustacea: Penaeidea). The peptides can be arranged in seven sub-groups according to the variable post-tyrosyl residue represented ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(02)00035-9
更新日期：2002-06-01 00:00:00
abstract：:Urotensin-II (U-II), a ligand for the G-protein-coupled receptor UT, has been characterized as the most potent mammalian vasoconstrictor identified to date. Although circulating levels of U-II are altered in lower species (e.g., fish) upon exposure to hypo-osmotic stress, little is known about the actions of this cycl...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2005.10.004
更新日期：2006-06-01 00:00:00
abstract：:Oxyntomodulin (OXM), a 37-amino acid glucagon-containing peptide produced mainly in intestine and endocrine pancreas, is present in rat plasma and inhibits pentagastrin-stimulated gastric acid secretion in both the anesthetized and the conscious rat. In order to investigate the modifications in acid and water secretio...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(86)90196-8
更新日期：1986-01-01 00:00:00
abstract：:This study sought to determine the serum levels of chemerin in gastric cancer patients and healthy subjects and to investigate the biological effect of chemerin on gastric cancer cells. Serum chemerin level of 36 gastric cancer patients and 40 healthy subjects was measured by enzyme-linked immunosorbent assay. AGS and...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2013.10.009
更新日期：2014-01-01 00:00:00
abstract：:This study determined the long-term influence of prenatal nicotine exposure (PN) on blood pressure and vascular functions in the aged offspring rats. PN did not affect body weight and plasma adrenocorticotropic hormone level; however, it significantly reduced plasma angiotensin I and angiotensin II in both sexes. Syst...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2013.02.019
更新日期：2013-06-01 00:00:00
abstract：:Studies were conducted in order to determine if selected neurons could be isolated from the brain using Sepharose-linked recognition complexes directed against or related to the biosynthetic/neurosecretory product of the desired neuronal population. Immunoreactive LRF neurons were precipitated when dispersed cells of ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(85)90061-0
更新日期：1985-03-01 00:00:00
abstract：:The involvement of spinal opioid receptors and spinal monoaminergic systems, in the antinociceptive effect of intrathecal (IT) salmon calcitonin, has been evaluated by means of the hot plate test, in the rat. Intrathecal pretreatment with 40 micrograms MR 1452 and 40 micrograms ICI 154,129, purported selective antagon...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(85)90385-7
更新日期：1985-01-01 00:00:00
abstract：:Effects of rat and human calcitonin gene-related peptide (r alpha CGRP and h beta CGRP, respectively) upon uterine contractile force were investigated using uterine horns from nonpregnant rats, r alpha CGRP and h beta CGRP were equipotent (pD2 = 8.85-9.09) in inhibiting spontaneous and electrically evoked uterine cont...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(90)90006-q
更新日期：1990-09-01 00:00:00
abstract：:This study was designed to test the possibility that antimicrobial peptides could be derived from the genomic sequences of phage lysins. Using two lysins (D3 and PhiKZ) we selected and produced two putative peptides (X and Z, respectively) believed to possess antimicrobial properties based on their physicochemical cha...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2005.07.001
更新日期：2006-01-01 00:00:00
abstract：:Crustacean hyperglycemic hormone (CHH) not only plays an important role in the modulation of hemolymph glucose level but also functions in other biological events including molting, reproduction and stress response. Of the six CHHs characterized in Marsupenaeus japonicus, an expression system for recombinant Pej-SGP-V...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2008.07.017
更新日期：2009-03-01 00:00:00
abstract：:Beta-amyloid (Aβ) peptides are secreted from neurons, resulting in extracellular accumulation of Aβ and neurodegeneration of Alzheimer's disease. Because neuronal secretion is fundamental for the release of neurotransmitters, this study assessed the hypothesis that Aβ undergoes co-release with neurotransmitters. Model...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2013.04.020
更新日期：2013-08-01 00:00:00
abstract：:The interaction of two cathelicidin antimicrobial peptides, LL-37 and SMAP-29, with three bacterial polysaccharides, respectively, produced by Pseudomonas aeruginosa, Burkholderia cepacia and Klebsiella pneumoniae, was investigated to identify possible mechanisms adopted by lung pathogens to escape the action of innat...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2005.01.020
更新日期：2005-07-01 00:00:00
abstract：:In a previous study, we found that calcitonin gene-related peptide (CGRP) could be induced by proinflammatory factor IL-1beta in A549 human type II alveolar (AEII) epithelial cells. We investigated the mechanism of IL-1beta-induced CGRP secretion and found that the PKC-p38 MAPK-NF-kappaB pathway was involved. In the p...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2007.03.021
更新日期：2007-06-01 00:00:00
abstract：:The beta-casein-derived octapeptide RINKKIEK is a noncompetitive inhibitor of soybean lipoxygenase (LOX). To investigate the molecular determinants for the enzyme-peptide interaction, a peptide library containing substitutional analogs of RINKKIEK was prepared by SPOT synthesis and analyzed for interaction with fluore...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2007.09.018
更新日期：2007-12-01 00:00:00
abstract：:A novel protease inhibitor, designated mungoin, with both antifungal and antibacterial activities, and exhibiting a molecular mass of 10kDa in SDS-polyacrylamide gel electrophoresis, was isolated from mung bean (Phaseolus mungo) seeds. The isolation procedure involved a combination of extraction, ammonium sulfate prec...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2006.07.013
更新日期：2006-12-01 00:00:00
abstract：:Melanin-concentrating hormone (MCH) is a hypothalamic peptide that plays a critical role in the regulation of food intake and energy metabolism. In this study, we investigated the potential role of dense hippocampal MCH innervation in the spatially oriented food-seeking component of feeding behavior. Rats were trained...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2015.12.007
更新日期：2016-02-01 00:00:00
abstract：:Neuropeptide Y (NPY) injected into the hypothalamus stimulates feeding and affects pituitary secretion. Insulin-deficient diabetes and food deprivation markedly increase hypothalamic NPY and NPY mRNA levels, suggesting increased activity of NPYergic pathways in the hypothalamus, which could account for hyperphagia and...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(93)90070-w
更新日期：1993-09-01 00:00:00
abstract：:The present studies were undertaken to better characterize the pharmacological properties of oxytocin receptors (OTRs) of the porcine kidney cell line, LLC-PK1, in their natural membranous environment and after solubilization. In intact membranes, binding of a selective radioligand was rapid, reversible, saturable, an...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(95)02121-3
更新日期：1996-01-01 00:00:00
abstract：:Osmotic stress stimulates the release of the avian hypothalamic neuropeptide arginine vasotocin (AVT) into the peripheral circulation. We conducted the present study to investigate the effects of salt-loading on AVT secretion and AVT gene expression in specific hypothalamic nuclei in chickens. White Leghorn chickens w...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(97)00190-3
更新日期：1997-01-01 00:00:00
abstract：:To investigate possible influences of growth hormone-releasing hormone (GHRH) and somatostatin (SRIF) on auditory perceptional processes, 12 subjects received either placebo (sodium chloride 0.9%), GHRH (50 micrograms), or SRIF (100 micrograms) on different days. Late auditory evoked potentials (AEP) were computed and...
journal_title：Peptides
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0196-9781(95)00024-e
更新日期：1995-01-01 00:00:00
abstract：:The reperfusion injury salvage kinase (RISK) pathway is a fundamental signal transduction cascade in the cardioprotective mechanism of ischemic postconditioning. In the present study, we examined the cardioprotective role of oxytocin as a postconditioning agent via activation of the RISK pathway (PI3K/Akt and ERK1/2)....
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2016.10.001
更新日期：2016-12-01 00:00:00
abstract：:Inhibitors of metallopeptidases may represent new alternatives in the treatment of cardiovascular disease. Recent investigations have linked the hypotensive properties of the metalloendopeptidase 3.4.24.15 (MEP 24.15) inhibitor c-phenylpropyl-alanyl-alanyl-phenylalanyl-para-aminobenzoate (cFP-A-A-F-pAB) to the attenua...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(92)90053-6
更新日期：1992-09-01 00:00:00
abstract：:The present study investigated the effects of neuropeptide Y (NPY) on food intake and body temperature (Tbo) in free-feeding unrestrained rats following injection into the medial hypothalamic paraventricular nucleus (PVN) or the lateral perifornical hypothalamus (PFH). NPY (78-235 pmol) or saline was infused unilatera...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(95)00020-k
更新日期：1995-01-01 00:00:00
abstract：:The corpora cardiaca (CC) of two water bug species, the water boatman Corixa punctata and the saucer bug Ilyocoris cimicoides, contain a substance that cause hyperlipemia in the migratory locust. The primary sequence of one octapeptide belonging to the adipokinetic hormone (AKH)/red pigment-concentrating hormone (RPCH...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2006.11.019
更新日期：2007-03-01 00:00:00
abstract：:Cellular uptake of [125I] labelled DSIP at the luminal interface of the blood-brain barrier (BBB) was studied in the ipsilateral perfused in situ guinea pig forebrain. Regional unidirectional transfer constants (Kin) calculated from the multiple-time brain uptake analysis were 0.93, 1.33 and 1.66 microliter.min-1 g-1 ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(89)90026-0
更新日期：1989-03-01 00:00:00
abstract：:The striatum is richly innervated by both enkephalinergic and dopaminergic neurons, providing an anatomic framework from which intimate functional interrelationships between these neuronal systems may be postulated. Accordingly, many functional processes within dopamine neurons have been shown to be modulated by opioi...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(87)90014-3
更新日期：1987-05-01 00:00:00
abstract：:The melanocortin system has been implicated in a multitude of physiological pathways including obesity, satiety, energy homeostasis, sexual behavior, pigmentation, sodium regulation, hypertension, and many others. Based upon studies of the endogenous melanocortin receptor agonists at the cloned human melanocortin rece...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2010.08.025
更新日期：2010-12-01 00:00:00
abstract：:The functions of leptin receptors (LRs) are cell-type specific. At the blood-brain barrier, LRs mediate leptin transport that is essential for its CNS actions, and both endothelial and astrocytic LRs may be involved. To test this, we generated endothelia specific LR knockout (ELKO) and astrocyte specific LR knockout (...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2011.05.011
更新日期：2011-07-01 00:00:00
