Solubilization of oxytocin receptors in porcine renal LLC-PK1 cell membranes.

abstract：:Endomorphin1-ol (Tyr-Pro-Trp-Phe-ol, EM1-ol) and endomorphin2-ol (Tyr-Pro-Phe-Phe-ol, EM2-ol), with C-terminal alcohol (-ol) containing, have been shown to exhibit higher affinity and lower intrinsic efficacy in vitro than endomorphins. In the present study, in order to investigate the alterations of systemic hemodyna...

journal_title：Peptides

authors： Yu Y,Wang CL,Cui Y,Fan YZ,Liu J,Shao X,Liu HM,Wang R

更新日期：2006-01-01 00:00:00

abstract：:The binding of monoiodo 125I-Trp11-neurotensin to purified rat gastric fundus smooth muscle plasma membranes was characterized. Specific binding of ligand in subcellular fractions from rat fundus smooth muscle showed a distribution that paralleled that of several plasma membrane marker enzymes. 125I-Trp11-neurotensin ...

journal_title：Peptides

authors： Kitabgi P,Kwan CY,Fox JE,Vincent JP

更新日期：1984-09-01 00:00:00

abstract：:Suppression subtractive hybridization comparing brains from diapausing and nondiapausing pupae of the flesh fly, Sarcophaga crassipalpis, suggested that the gene encoding neuropeptide-like precursor 4 (Nplp4) was uniquely expressed during diapause. We have sequenced the full-length cDNA encoding Nplp4 and used Norther...

journal_title：Peptides

authors： Li A,Rinehart JP,Denlinger DL

更新日期：2009-03-01 00:00:00

abstract：:The localization of endozepine-like immunoreactivity in the brain of the frog Rana ridibunda was investigated by indirect immunofluorescence, using an antiserum against synthetic rat octadecaneuropeptide (ODN). A specific immunoreaction was detected in ependymal cells lining the ventricular system of the brain and in ...

journal_title：Peptides

authors： Malagon M,Vaudry H,Vallarino M,Gracia-Navarro F,Tonon MC

更新日期：1992-01-01 00:00:00

abstract：:The distribution of galanin-like immunoreactivity in the brain of the dogfish Scyliorhinus canicula was investigated using the indirect immunofluorescence technique. In the telencephalon, positive cells and fibers were located in the mid-caudal part of the area superficialis basalis, the n. septi caudoventralis and in...

journal_title：Peptides

authors： Vallarino M,Feuilloley M,Vandesande F,Vaudry H

更新日期：1991-03-01 00:00:00

abstract：:The in vitro interaction between five polycationic peptides, buforin II, cecropin P1, indolicidin, magainin II, and ranalexin, and several clinically used antimicrobial agents was evaluated against several clinical isolates of Gram-positive and Gram-negative aerobic bacteria, using the microbroth dilution method. The ...

journal_title：Peptides

authors： Giacometti A,Cirioni O,Del Prete MS,Paggi AM,D'Errico MM,Scalise G

更新日期：2000-08-01 00:00:00

abstract：:The discovery of several adipokines with diverse activities and their involvement in regulation of various pathophysiological functions of human body has challenged the researchers. In the family of adipokine, chemerin is a novel and unique addition. Ever since the first report on chemerin as a chemo-attractant protei...

journal_title：Peptides

authors： Fatima SS,Rehman R,Baig M,Khan TA

更新日期：2014-12-01 00:00:00

abstract：:Exposure of guinea pigs to the elevated plus maze (X-maze), an animal model of anxiety, causes an increase of extracellular serotonin (5-HT) in the lateral prefrontal cortex monitored by microdialysis. The neuropeptide cholecystokinin (CCK) plays a role in the modulation of anxiety. To compare the roles of CCK recepto...

journal_title：Peptides

authors： Rex A,Fink H

更新日期：1998-01-01 00:00:00

abstract：:We performed the first comprehensive peptidomic analysis of neurohormones from hemipteran insects by analyzing the neuropeptides of two major neurohemal organs, namely the corpora cardiaca and abdominal perisympathetic organs. For the experiments we selected four related species of polyphagous stinkbugs (Pentatomidae)...

journal_title：Peptides

authors： Predel R,Russell WK,Russell DH,Lopez J,Esquivel J,Nachman RJ

更新日期：2008-02-01 00:00:00

abstract：:The effects of dipeptide cyclo-[His-Pro] (CHP), known to participate in the appetite behavior and food intake control, have been investigated using PC12 cells in culture as model system. We found that only in the presence of experimental conditions that cause cellular stress the cyclic dipeptide affect cellular prolif...

journal_title：Peptides

authors： Minelli A,Bellezza I,Grottelli S,Pinnen F,Brunetti L,Vacca M

更新日期：2006-01-01 00:00:00

abstract：:Malaria lactate dehydrogenase, a glycolytic enzyme, is a malaria diagnostic target in lateral flow immunochromatographic rapid diagnostic tests. Recombinant Plasmodium yoelii LDH was cloned into the pET-28a vector, expressed and the expressed protein purified from a Ni-NTA affinity matrix. A pan-malarial LDH antibody ...

journal_title：Peptides

authors： Hurdayal R,Achilonu I,Choveaux D,Coetzer TH,Dean Goldring JP

更新日期：2010-04-01 00:00:00

abstract：:Peptides spanning the range of human parathyroid hormone-related protein (PTHrP) have been shown to bind heat shock protein-70 expressed on the surface of cancer cells with cytoprotective consequences in vitro. The present study focused on identification of intracellular proteins that interact with the carboxy-termina...

journal_title：Peptides

authors： Grzesiak JJ,Burton DW,Deftos LJ,Bouvet M

更新日期：2006-07-01 00:00:00

abstract：:High performance-gel permeation chromatography (HP-GPC) evaluation of human plasma and serum incubated at 37 degrees C up to 24 h after the addition of long-acting natriuretic peptide (LANP) revealed a 25% decrease in LANP's peak at 2 h followed by an increase in plasma without EDTA at 8 h (p < 0.001). Vessel dilator'...

journal_title：Peptides

authors： Overton RM,Vesely DL

更新日期：1996-01-01 00:00:00

abstract：:Urotensin-II (U-II), a cyclic peptide widely expressed in blood vessels, has diverse vascular actions that range from potent vasoconstriction to vasodilation. Although, U-II-induced vasodilation has been shown to be partially dependent on nitric oxide (NO), the involvement of vascular adventitia-derived NO, remains un...

journal_title：Peptides

authors： Lin L,Ding WH,Jiang W,Zhang YG,Qi YF,Yuan WJ,Tang CS

更新日期：2004-11-01 00:00:00

abstract：:The elevated T-maze was combined with a free exploration protocol, which, in contrast to the conventional procedure, dispenses with handling of the animals during the experimental sessions. This allows measurement of fear indexes derived from the elevated plus-maze as well as assessment of acquisition of open arm avoi...

journal_title：Peptides

authors： Echeverry MB,Hasenöhrl RU,Huston JP,Tomaz C

更新日期：2001-07-01 00:00:00

abstract：:The thyroid gland is known to harbor cholinergic and VIPergic nerves. In the present study, the influences of cholinergic stimulation by carbachol, cholinergic blockade by methylatropine and stimulation with various VIP sequences on basal, TSH-induced and VIP-induced thyroid hormone section were investigated in vivo i...

journal_title：Peptides

authors： Ahrén B

更新日期：1985-07-01 00:00:00

abstract：:Neuromedin B (NMB), which was originally isolated from porcine spinal cord, is a mammalian bombesin-related peptide that exerts various physiological effects. Previously, we observed expression of NMB in rib cartilage from chicken. Here, we report the initial attempt to elucidate the role of NMB in cartilage. We used ...

journal_title：Peptides

authors： Saito H,Ikeda R,Inoue K,Nagata S,Kitamura K,Minamino N,Kangawa K,Miyata A

更新日期：2012-08-01 00:00:00

abstract：:Subpopulations of dopamine (DA) neurons in the ventral mesencephalon have been reported to contain cholecystokinin (CCK) and neurotensin (NT), giving rise to DA, DA/NT, NT/CCK and DA/CCK/NT projections. More precisely, colocalized DA/CCK neurons project mainly to the caudal part of the medial nucleus accumbens, wherea...

journal_title：Peptides

authors： Heidbreder C,Gewiss M,De Mot B,Mertens I,De Witte P

更新日期：1992-05-01 00:00:00

abstract：:The aim of this study was to compare the actions of CCK neuropeptides within the nucleus accumbens (N.Acc) of alcohol preferring (Fawn-Hooded, FH) and alcohol nonpreferring (Wistar-Kyoto, WKY) rats. CCK-8S (30-300 nM) facilitated the K(+) stimulated release of [(3)H]dopamine (DA) from N.Acc prisms in both rat strains,...

journal_title：Peptides

authors： Lodge DJ,Short JL,Mercer LD,Beart PM,Lawrence AJ

更新日期：2000-03-01 00:00:00

abstract：:Amyloid deposition in Alzheimer fibrils forms neurotoxic senile plaques in a process that may be modulated by associated proteins. In this work we demonstrate the ability of laminin-1 and laminin-2 to inhibit fibril formation and toxicity on cultured rat hippocampal neurons. We confirm that the laminin-1-derived pepti...

journal_title：Peptides

authors： Morgan C,Bugueño MP,Garrido J,Inestrosa NC

更新日期：2002-07-01 00:00:00

abstract：:Orexin is one of the orexigenic neuropeptides in the hypothalamus. Orexin neurons in the lateral hypothalamus (LH) project into the cerebral cortex and hippocampus in which the receptors are distributed in high concentrations. Therefore, to elucidate the actions of orexin in the cerebral cortex, we examined its effect...

journal_title：Peptides

authors： Yamada N,Katsuura G,Tatsuno I,Asaki T,Kawahara S,Ebihara K,Saito Y,Nakao K

更新日期：2008-09-01 00:00:00

abstract：:The double-stranded RNA dependent protein kinase (PKR) is a negative regulator of cell proliferation and thus itself a target for modulation. We show that a cell-permeable peptide (PRI), containing a conserved double-stranded RNA binding motif found in PKR, inhibits activation of the kinase and activity to phosphoryla...

journal_title：Peptides

authors： Nekhai S,Bottaro DP,Woldehawariat G,Spellerberg A,Petryshyn R

更新日期：2000-10-01 00:00:00

abstract：:Thirty viral proteomes were examined for amino acid sequence similarity to the human proteome, and, in parallel, a control of 30 sets of human proteins was analyzed for internal human overlapping. We find that all of the analyzed 30 viral proteomes, independently of their structural or pathogenic characteristics, pres...

journal_title：Peptides

authors： Kanduc D,Stufano A,Lucchese G,Kusalik A

更新日期：2008-10-01 00:00:00

abstract：:Elucidating how neuropeptides affect physiology may result in delineating peptidergic mechanisms and identifying antagonists for application in basic and translational science. Human neuropeptide Y (NPY) regulates cardiac activity; frequently invertebrates contain orthologs of vertebrate peptides. We report invertebra...

journal_title：Peptides

authors： Setzu M,Biolchini M,Lilliu A,Manca M,Muroni P,Poddighe S,Bass C,Angioy AM,Nichols R

更新日期：2012-02-01 00:00:00

abstract：:Broad-spectrum antiviral drugs are urgently needed to treat individuals infected with new and re-emerging viruses, or with viruses that have developed resistance to antiviral therapies. Mammalian natural host defense peptides (mNHP) are short, usually cationic, peptides that have direct antimicrobial activity, and whi...

journal_title：Peptides

authors： Sample CJ,Hudak KE,Barefoot BE,Koci MD,Wanyonyi MS,Abraham S,Staats HF,Ramsburg EA

更新日期：2013-10-01 00:00:00

abstract：:The aim of the present study was to investigate how suckling influences the plasma levels of oxytocin and vasoactive intestinal peptide in lactating dogs. Blood-samples were drawn from ten lactating beagles during suckling, in week one and week three of the five week long lactation period and the levels of vasoactive ...

journal_title：Peptides

authors： Eriksson M,Lindén A,Stock S,Uvnäs-Moberg K

更新日期：1987-05-01 00:00:00

abstract：:Ghrelin is broadly expressed in myocardial tissues, where it exerts different functions. It also has been found to have a wide variety of biological functions on cell differentiation and tissue development. The aim of this study was to investigate the effect of ghrelin on human embryonic stem cell (hESC) differentiati...

journal_title：Peptides

authors： Gao M,Yang J,Liu G,Wei R,Zhang L,Wang H,Wang G,Gao H,Chen G,Hong T

更新日期：2012-04-01 00:00:00

abstract：:Cellular actions of nociceptin/orphanin FQ (N/OFQ) resemble those of micro-, delta-, and kappa-opioids, i.e. activation of inwardly rectifying K(+) conductance, inhibition of high-voltage-activated Ca(2+) channel currents, and impediment of neurotransmitter release. Differences in ORL(1) and micro-receptor distributio...

journal_title：Peptides

authors： Moran TD,Abdulla FA,Smith PA

更新日期：2000-07-01 00:00:00

abstract：:More than 40 peptides belonging to the -Y/FXFGL-NH(2) allatostatin superfamily have been isolated and identified from the central nervous system (CNS) of the tiger prawn, Penaeus monodon (Crustacea: Penaeidea). The peptides can be arranged in seven sub-groups according to the variable post-tyrosyl residue represented ...

journal_title：Peptides

authors： Duve H,Johnsen AH,Scott AG,Thorpe A

更新日期：2002-06-01 00:00:00

abstract：:Multiple-time regression analysis has been used to study the influx of radiolabeled peptides and polypeptides across the blood-brain barrier (BBB). This study used both tritiated and iodinated leptin to clarify several issues associated with these measurements. Recombinant murine leptin was radiolabeled with 3H by der...

journal_title：Peptides

authors： Kastin AJ,Akerstrom V,Pan W

更新日期：2001-12-01 00:00:00