Abstract:
:MicroRNAs (miRNAs) are a group of endogenous noncoding small RNAs characterized by high conservation; furthermore, various studies have shown the capability of miRNAs to impact diseases. For example, a study shows that cell-free miRNAs are stable in bodily fluids, which gives circulating miRNAs the ability to be potential biomarkers for noninvasive diagnosis. Additionally, accumulating studies have supported that miRNAs can function as suppressor genes, again demonstrating their effect on disease. This review introduces this particular role of miRNAs as well as analyzes the prospect of miRNAs as biomarkers and the capacity for using miRNA-based resources to benefit mankind.
journal_name
Biomed Mater Engjournal_title
Bio-medical materials and engineeringauthors
Xu L,Qi X,Duan S,Xie Y,Ren X,Chen G,Yang X,Han L,Dong Qdoi
10.3233/BME-141223subject
Has Abstractpub_date
2014-01-01 00:00:00pages
3917-25issue
6eissn
0959-2989issn
1878-3619pii
W011711172037574journal_volume
24pub_type
杂志文章,评审abstract::Alginate hydrogels have been used widely in tissue engineering for cell encapsulation for several reasons: low toxicity, the ability to gel under gentle condition and compatibility with cells. In this study, we determined the effect of different concentrations of alginate on encapsulation of 3T3 fibroblast cells at tw...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2011-0665
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Electrospinning is a highly effective method in order to generate nano-scaled fibers. In conventional electrospinning technique, geometry of nanofibers are mostly random due to the chaotic behavior of polymer jet. OBJECTIVE:Purpose of this study is to produce aligned nanofibers from PVP polymers with advanc...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-181017
更新日期:2018-01-01 00:00:00
abstract::Porous polyethylene (PP or Medpor) is an alloplastic material worldwide used for craniofacial reconstruction. Although several clinical studies are available, there is a lack as regard the genetic effects. Because PP is always fixed on bone and the mechanism by which PP acts on osteoblasts is unknown, we therefore att...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::Various tissue-engineered vascular grafts have been studied in order to overcome the clinical disadvantages associated with conventional prostheses. However, previous tissue-engineered vascular grafts have possessed insufficient mechanical properties and thus have generally required either preoperative cellular manipu...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141023
更新日期:2014-01-01 00:00:00
abstract::Poly(N-substituted alpha/beta-asparagine) was evaluated as a thermoresponsible and an injectable scaffold for cartilage regeneration. Solutions of this polymer are liquid state below 25 degrees C and nonfluid hydrogel above 35 degrees C, allowing an aqueous solution containing cells at room temperature to form a hydro...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Motor imagery EEG-based BCI has advantages in the assistance of human control of peripheral devices, such as the mobile robot or wheelchair, because the subject is not exposed to any stimulation and suffers no risk of fatigue. However, the intensive training necessary to recognize the numerous classes of data makes it...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151409
更新日期:2015-01-01 00:00:00
abstract::Level set method has been widely used in medical image analysis, but it has difficulties when being used in the segmentation of left ventricular (LV) boundaries on echocardiography images because the boundaries are not very distinguish, and the signal-to-noise ratio of echocardiography images is not very high. In this...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151427
更新日期:2015-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-180999
更新日期:2018-01-01 00:00:00
abstract::Microarray data has small samples and high dimension, and it contains a significant amount of irrelevant and redundant genes. This paper proposes a hybrid ensemble method based on double disturbance to improve classification performance. Firstly, original genes are ranked through reliefF algorithm and part of the gene...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151499
更新日期:2015-01-01 00:00:00
abstract::Mesenchymal stem cells (MSCs) are a common tool in regenerative medicine. The nanoscale extracellular vesicles (nEVs) secreted by these cells were recently brought up to light thanks to their therapeutic potential. In this study, we assessed the in vitro behaviour of human umbilical vein endothelial cells (HUVECs) exp...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171626
更新日期:2017-01-01 00:00:00
abstract::Sino-atrial node cells (SANCs) play a significant role in rhythmic firing. To investigate their role in arrhythmia and interactions with the atrium, computer simulations based on cellular dynamic mathematical models are generally used. However, the large-scale computation usually makes research difficult, given the li...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151365
更新日期:2015-01-01 00:00:00
abstract::This paper presents the single channel speech enhancement system using subband Kalman filtering by estimating optimal Autoregressive (AR) coefficients and variance for speech and noise, using Weighted Linear Prediction (WLP) and Noise Weighting Function (NWF). The system is applied for normal and Oesophageal speech si...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141183
更新日期:2014-01-01 00:00:00
abstract::The present review surveys studies on physical-chemical properties and biological response of living tissues to NiTi (Nitinol) carried out recently, aiming at an understanding of the place of this material among the implant alloys in use. Advantages of shape memory and superelasticity are analyzed in respect to functi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract::In recent years, there is an increasing utilization and demand to use magnetic fields in bioengineering applications due to its beneficial effects. Although in the last decade more attention has been given by tribologists to the electromagnetic processes taking place between sliding surfaces, which influence the tribo...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::To investigate the inhibition effect of oxymatrine induces human lung cancer A549 cells apoptosis. The A549 cells were cultured for 24 h, than the various concentration of oxymatrine (2 mmol/L, 4 mmol/L, 8 mmol/L, 15 mmol/L) were added into different experimental group cells, and 5-fluorouracil were added into the pos...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151302
更新日期:2015-01-01 00:00:00
abstract::The selection of best material pair in the hip prosthetics design for improved performance and life relies on the estimation of hip joint contact stresses and contact pressure distribution during various dynamic loading cycles: Climbing Upstairs, Climbing downstairs and Knee bending. The maximum Von Mises stress, cont...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-181019
更新日期:2018-01-01 00:00:00
abstract::This study investigates the radiation safety of a newly designed magnetic induction sensor. This novel magnetic induction sensor uses a two-arm Archimedean spiral coil (TAASC) as the exciter. A human head model with a real anatomical structure was used to calculate the specific absorption rate (SAR) and temperature ch...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151329
更新日期:2015-01-01 00:00:00
abstract::To select tag single nucleotide polymorphisms (SNPs) within and around human p75 neurotrophin receptor (p75NTR) gene in Chinese Han population, the sequence involving p75NTR gene as well as the upstream and downstream of the gene was identified according to the data from National Center for Biotechnology Information (...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141213
更新日期:2014-01-01 00:00:00
abstract::Gabexate mesilate is a non-peptide protease inhibitor, developed in Japan, which is used in the treatment of acute pancreatitis and disseminated intravascular coagulation. This compound is readily hydrolyzed as it has ester bonds in its structure. It is now out of patent in Japan and there are many generic versions on...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2010-0611
更新日期:2010-01-01 00:00:00
abstract::The aim of this study is to verify the effect of indoor horse riding exercise on basal physical exercise and lumbar muscular function. The subjects included were 20 healthy females, who participated in the horse riding exercise using SRider (Rider Co. & ChonbuK National Univ, Korea) for 30 minutes per day, 3 days per ...
journal_title:Bio-medical materials and engineering
pub_type: 临床试验,杂志文章
doi:10.3233/BME-141053
更新日期:2014-01-01 00:00:00
abstract::A crucial role during the implementation of volume visualization is to identify the optimal transfer function, since the vital information and structure can be highlighted and revealed. The boundary of the volume is shared by respective portion of the two materials formed out of it, which causes undesirable thickening...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141123
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Stenting has been proposed as an effective treatment to restore blood flow in obstructed arteries by plaques. Although several modified designs for stents have been suggested, most designs have the risk of disturbing blood flow. OBJECTIVE:The main objective is to propose a stent design to attain a uniform l...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171691
更新日期:2017-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-181737
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Previously we found that a group of phosphorylated proteins (SIBLINGs) in bone binds with the Ti-device, and increases the early bone formation around the Ti-implants remarkably. From these results, we explained the biochemical mechanism of a strong bond between living bone and Ti, which was discovered by Br...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-201079
更新日期:2020-01-01 00:00:00
abstract::Longitudinal stent compression (LSC) is a new failure mode not previously observed in coronary stents. This phenomenon occurs when the physician tries to cross the deployed stent with other devices. While this phenomenon has been observed with a number of stent designs, it seems more common with the Element stent. A c...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130781
更新日期:2014-01-01 00:00:00
abstract::Electroencephalograph (EEG) signals feature extraction and processing is one of the most difficult and important part in the brain-computer interface (BCI) research field. EEG signals are generally unstable, complex and have low signal-noise ratio, which is difficult to be analyzed and processed. To solve this problem...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141113
更新日期:2014-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::We previously reported a simple method for the preparation of size-controlled spherical silver nanoparticles (Ag NPs) generated by autoclaving a mixture of silver-containing glass powder and glucose. The particle size is regulated by the glucose concentration, with concentrations of 0.25, 1.0 and 4.0 wt% glucose provi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130772
更新日期:2013-01-01 00:00:00
abstract::Morse code is now being harnessed for use in rehabilitation applications of augmentative-alternative communication and assistive technology, including mobility, environmental control and adapted worksite access. In this paper, Morse code is selected as a communication adaptive device for disabled persons who suffer fr...
journal_title:Bio-medical materials and engineering
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Most drug delivery systems as treatment modalities for osteomyelitis have not been evaluated for resistant infections. Tigecycline (TG) is an antimicrobial agent that could be used in the treatment of multi-drug-resistant orthopedic infections. The objective of this in vitro study has been to determine what dosage of ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-140978
更新日期:2014-01-01 00:00:00