Abstract:
:Mesenchymal stem cells (MSCs) are a common tool in regenerative medicine. The nanoscale extracellular vesicles (nEVs) secreted by these cells were recently brought up to light thanks to their therapeutic potential. In this study, we assessed the in vitro behaviour of human umbilical vein endothelial cells (HUVECs) exposed to nEVs derived from human umbilical cord mesenchymal stem cells (hUC-MSCs). Nanoscale extracellular vesicles were isolated and characterized by NanoSight® and flow cytometry. HUVECs were stimulated with various concentrations of nEVs. To assess nEV interactions with HUVECs, confocal microscopy and angiogenesis assay were performed. The use of nEVs derived from hUC-MSCs was able to produce positive outcomes on HUVECs by acting on their angiogenic potential.
journal_name
Biomed Mater Engjournal_title
Bio-medical materials and engineeringauthors
Dostert G,Willemin AS,Jouan-Hureaux V,Louis H,Hupont S,Gillet P,Menu P,Decot V,Moby V,Velot Édoi
10.3233/BME-171626subject
Has Abstractpub_date
2017-01-01 00:00:00pages
S75-S79issue
s1eissn
0959-2989issn
1878-3619pii
BME1626journal_volume
28pub_type
杂志文章abstract::Crystalline hydroxyapatite (HA) powder was coated on titanium substrate by radio frequency (RF) magnetron sputtering. The coating was homogeneous thin film and the thickness was 1microm. Crystallinity of the HA coating was low and Ca/P ratio was high as 3.0. Particle sizes were 40 to approximately 100 nm, and the crys...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Surface replication is a nondestructive evaluation technique applied in examining surface wear by recording surface irregularities, especially in conditions when surfaces of interest cannot be further manipulated to fit directly under a microscope to be examined. Enamel is the outermost protective layer of t...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-206006
更新日期:2020-01-01 00:00:00
abstract::To investigate the inhibition effect of oxymatrine induces human lung cancer A549 cells apoptosis. The A549 cells were cultured for 24 h, than the various concentration of oxymatrine (2 mmol/L, 4 mmol/L, 8 mmol/L, 15 mmol/L) were added into different experimental group cells, and 5-fluorouracil were added into the pos...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151302
更新日期:2015-01-01 00:00:00
abstract::Level set method has been widely used in medical image analysis, but it has difficulties when being used in the segmentation of left ventricular (LV) boundaries on echocardiography images because the boundaries are not very distinguish, and the signal-to-noise ratio of echocardiography images is not very high. In this...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151427
更新日期:2015-01-01 00:00:00
abstract::Fifty two ceramic femoral heads have been investigated after implantation. All heads had articulated against ultra high molecular weight polyethylene (UHMWPE) cups. Examination of the heads shows changes in sphericity and surface roughness due to the wear. The behaviour of these retrieved heads after clinical use conf...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::In recent years, there is an increasing utilization and demand to use magnetic fields in bioengineering applications due to its beneficial effects. Although in the last decade more attention has been given by tribologists to the electromagnetic processes taking place between sliding surfaces, which influence the tribo...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::A layer of L-glycine-molecule-imprinted polyaniline (LMIP-PANI) polymer film has been modified on a carbon fiber electrode for the determination of L-glycine standard samples and L-glycine in cerebrospinal fluid of wistar mice. It has been found that a linear relationship exists between current and concentration for t...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130907
更新日期:2014-01-01 00:00:00
abstract::Low-dose computed tomography reconstruction is an important issue in the medical imaging domain. Sparse-view has been widely studied as a potential strategy. Compressed sensing (CS) method has shown great potential to reconstruct high-quality CT images from sparse-view projection data. Nonetheless, low-contrast struct...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151437
更新日期:2015-01-01 00:00:00
abstract::Chitosan oligosaccharides graft polycaprolactone copolymer (PHCSO-g-PCL) has been synthesized via initiating the polymerization of e-caprolactone (CL) monomer through an amino group protection route using phthaloyl chitosan oligosaccharide (PHCSO) as intermediate. The grafting reaction was carried out in Pyridine at 1...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141013
更新日期:2014-01-01 00:00:00
abstract::The effect of carbonate in reducing the crystal size of precipitated hydroxyapatite by approximately an order of magnitude has not been used previously in the preparation of gel monoliths for the fabrication of carbonate hydroxyapatite ceramics. The aim of this study was to devise a method whereby gel monoliths of car...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Great potential of cellular therapies has generated extensive research in the field of cells harvesting and culturing. Transplantation of cell cultures has been used in a variety of therapeutic programs but in many cases it appeared that biomaterial scaffold or sheath would enhance cells regenerative potenti...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-140966
更新日期:2014-01-01 00:00:00
abstract::To evaluate the influence of Zn on the formation of hydroxyapatite (HA), zinc-containing glass 58S4Z was prepared by substitution of CaO with 4 wt% ZnO in 58S bioactive glass, and Zn-containing simulated body fluid (ZnSBF) was prepared as soaking fluid. During the soaking, all samples could induce the deposition of HA...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Some computer applications for cell characterization in medicine and biology, such as analysis of surface structure of cell wall-deficient EVC (El Tor Vibrio of Cholera), operate with cell samples taken from very small areas of interest. In order to perform texture characterization in such an application, only a few t...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Stroke is a major cause of death and disability throughout the world. Subtotal occlusion of the carotid artery is an important risk factor for stroke. Carotid artery stenting (CAS) is increasingly being used for treatment of carotid artery stenosis. There are many reports on treating carotid artery stenosis by CAS; ho...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2012-0687
更新日期:2012-01-01 00:00:00
abstract::This paper explores mouse kidney imaging with diffraction enhanced imaging (DEI) and inline outline X-ray imaging (IOXI) technology, and evaluates latent value of kidney imaging with phase contrast imaging technology. In our experiment, spatial resolution and tissue contrast serve as element evaluation and comparison....
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130917
更新日期:2014-01-01 00:00:00
abstract::In order to investigate the significance of hydroxyapatite based microporous composite (HA/mica composite) surfaces and a macroporous synthetic hydroxyapatite, rat marrow cell culture, which shows osteogenic differentiation, was carried out on six different culture substrata (two control culture dishes, two identical ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::The aim of the present study was to determine the degradability of aliphatic polyurethanes, based on a different amount of synthetic, atactic poly[(R,S)-3-hydroxybutyrate] (a-PHB), in hydrolytic (phosphate buffer) and oxidative (H2O2/CoCl2) solutions. The soft segments were built with atactic poly[(R,S)-3-hydroxybutyr...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151262
更新日期:2015-01-01 00:00:00
abstract::The interaction between implant materials and bone cells or oral epithelial (OE) cells contributes to the clinical success of dental implants. The functional activity of cells in contact with an implant is determined by its surface properties. Before cells attach, extracellular matrix (ECM) in the serum deposits on th...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:
更新日期:2004-01-01 00:00:00
abstract::Since adhesive technology was introduced into dental field, metal-based restoration has been gradually replaced by metal-free restoration. Using the adhesive technology, minimum invasive technique has been possible in daily clinical practice as well as esthetic tooth-colored restorations have become very popular all o...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:10.3233/BME-2009-0587
更新日期:2009-01-01 00:00:00
abstract::An acid-base resistant zone (ABRZ) has been shown to be created under a hybrid layer in a self-etching adhesive system at the adhesive/dentin interface. The purpose of this study was to assess the nanostructure of the ABRZ by applying all-in-one adhesive systems. Human premolar dentin was treated with one of two all-i...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2009-0576
更新日期:2009-01-01 00:00:00
abstract::Food systems are complex and inhomogeneous in nature. Ultrasonic propagation velocity in the food systems, in this case processed milk cream and vegetable oils, is studied. Ultrasonic properties of the food systems are similar to those of complex biological tissues. The presence of vegetable oil as an adulterant in th...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::In this investigation, ultrasonic parameters of kidney stones are measured, in vitro, using a double probe ultrasonic-through-transmission technique. Due to the complex chemical structure of these stones, a large variation in the values of the ultrasonic parameters is found. A correlation between ultrasonic properties...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::A fracture mechanics approach has been adopted in the present study to investigate the fracture toughness behavior of three commercial composite resins for dental use named Clearfil photo posterior, P-50 and Occlusin. The resins have been cast in to ring-shaped specimens for the determination of individual fracture to...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Intraocular lenses (IOL) made of polymethyl methacrylate (PMMA) lack an important yellowish pigment useful as a filter in the visual process and in the protection of the retina from short wavelength light. It was found that the PMMA used for IOL manufacturing can be tinted by dry exposure to mercury near-UV emitting l...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:Repairing contour defects is a challenge in plastic surgery. Different filling materials have been used with inadequate results and complications. The autologous fat transfer is the standard technique at the moment, but adipose tissue reserves are limited. The aim of our study was to compare in vivo on an ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::This study aimed to determine the optimal starting material for the development of an acellular osteochondral graft. Osteochondral tissues from three different species were characterised; pig (6 months), cow (18 months) and two ages of sheep (8-12 months and >4 year old). Tissues from the acetabulum and femoral head o...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151533
更新日期:2015-01-01 00:00:00
abstract::Various tissue-engineered vascular grafts have been studied in order to overcome the clinical disadvantages associated with conventional prostheses. However, previous tissue-engineered vascular grafts have possessed insufficient mechanical properties and thus have generally required either preoperative cellular manipu...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141023
更新日期:2014-01-01 00:00:00
abstract::Arrhythmia diagnosis is very significant to ensure human health. In this paper, a new model is developed for arrhythmia diagnosis. A salient feature of the algorithm is a synergistic combination of statistical and fuzzy set-based techniques. It is distribution-free and is realized in an unsupervised mode. Arrhythmia d...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151400
更新日期:2015-01-01 00:00:00
abstract::To build a patient specific respiratory motion model with a low dose, a novel method was proposed that uses a limited number of 3D lung CT volumes with an external respiratory signal. 4D lung CT volumes were acquired for patients with in vitro labeling on the upper abdominal surface. Meanwhile, 3D coordinates of in vi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141133
更新日期:2014-01-01 00:00:00
abstract::Dry emulsion containing curcumin (DE-CUR) was prepared for oral delivery of poorly water-soluble curcumin, and its oral bioavailability and antiasthmatic efficacy was evaluated. After comparison of the solubility of curcumin in various oils, Plurol® Oleique CC497 was selected to be the oil phase due to its higher solu...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130886
更新日期:2014-01-01 00:00:00