A molecule-imprinted polyaniline membrane modified on carbon fiber for detection of glycine.

Abstract:

:A layer of L-glycine-molecule-imprinted polyaniline (LMIP-PANI) polymer film has been modified on a carbon fiber electrode for the determination of L-glycine standard samples and L-glycine in cerebrospinal fluid of wistar mice. It has been found that a linear relationship exists between current and concentration for the glycine standard samples in the range of 0-12 μM by using the LMIP-PANI-modified carbon fiber electrode as a sensor. However, there is no any relationship between current and concentration for the carbon fiber electrode modified with no-glycine-molecule-imprinted polyaniline (NIP-PANI). The MIP-PANI- and NIP-PANI-modified carbon fiber films have been characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and electrochemistry methods. The investigation shows that the MIP-PANI-imprinted carbon fiber electrode will have a potential application in in-situ monitoring neurotransmitter due to its easy fabrication, low cost, bio-compatibility and flexibility.

journal_name

Biomed Mater Eng

authors

Zeng H,Wang D,Yu J

doi

10.3233/BME-130907

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

1085-91

issue

1

eissn

0959-2989

issn

1878-3619

pii

E7J01V20528W2470

journal_volume

24

pub_type

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