Abstract:
:One goal of functional tissue engineering is to manufacture scaffolds infiltrated with chondrocytes which are suitable for transplantation into the lesion areas of articular cartilage. Various research strategies are used to fabricate cartilage transplants which would have the correct phenotype, contain enough extracellular matrix components, and have structural and biomechanical properties equivalent to normal articular cartilage. We have investigated the suitability of viscose cellulose sponges as a scaffold for cartilage tissue engineering. The sponges were tested alone, or with recombinant human type II collagen cross-linked inside the material. Scanning electron microscopy and confocal microscopy were used to study the structure of the scaffold during four weeks of cultivation. Cellulose and cellulose/recombinant type II collagen sponges were biocompatible for at least four weeks in cultivation, and gradual filling of the scaffold was observed. However, the constructs remained soft during the observation period, and were devoid of extracellular matrix composition typical for normal articular cartilage.
journal_name
Biomed Mater Engjournal_title
Bio-medical materials and engineeringauthors
Pulkkinen H,Tiitu V,Lammentausta E,Laasanen MS,Hämäläinen ER,Kiviranta I,Lammi MJsubject
Has Abstractpub_date
2006-01-01 00:00:00pages
S29-35issue
4 Suppleissn
0959-2989issn
1878-3619journal_volume
16pub_type
杂志文章abstract::A novel technique and product for carpal tunnel microscopic surgical procedures using a modified medical device containing a head as a surgical scalpel under light guidance were designed and studied. The novel design of the medical device was developed and applied in a new carpal tunnel microscopic surgical procedure ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151303
更新日期:2015-01-01 00:00:00
abstract::DNA-binding proteins are involved and play a crucial role in a lot of important biological processes. Hence, the identification of the DNA-binding proteins is a challenging and significant problem. In order to reveal the intrinsic information correlated to DNA-binding, nine classes of candidate features based on diffe...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151491
更新日期:2015-01-01 00:00:00
abstract::The hip stem design based upon X-ray films requires sufficient information in order to customize for the patient. If the errors are resulted from rotating angles, more X-ray films may carry out the solution. The present study aimed to realize the improvement of multiple X-ray films for hip stem design. Eight X-ray fil...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::We have developed a novel multicomponent nano-hydroxyapatite-poly(D,L-lactide-co-glycolide)-collagen biomaterial (nHAP-PLGA-collagen) with mechanical properties similar to human cancellous bone. To demonstrate the bone forming capacity of nHAP-PLGA-collagen prior to in vivo experiments, nHAP-PLGA-collagen films and 3D...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171703
更新日期:2017-01-01 00:00:00
abstract::Recent advances of fundamental research on the in vitro generation of red blood cells (RBCs) from hematopoietic stem cells in the laboratory open new possibilities of the utilization of cultured RBCs in transfusion medicine. We study the economic challenge of the setup and development of the mass industrial production...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141251
更新日期:2015-01-01 00:00:00
abstract::Biocompatible metals have been suggested as revolutionary biomaterials for bone-grafting therapies. Although metals and their alloys are widely and successfully used in producing biomedical implants due to their good mechanical properties and corrosion resistance, they have a lack in bioactivity. Therefore coating of ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:10.3233/BME-161568
更新日期:2016-05-12 00:00:00
abstract:BACKGROUND:Age is the most important risk factor for primary osteoarthritis (OA). Members of the TGF-β superfamily play a crucial role in chondrocyte differentiation and maintenance of healthy articular cartilage. OBJECTIVE:We have investigated whether age-related changes in TGF-β superfamily signaling components play...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-140976
更新日期:2014-01-01 00:00:00
abstract::The method of formation of bioactive calcium-phosphate coating on medical titanium alloy Ti-6Al-4V (3.5-5.3% V; 5.3-6.8% Al; balance -Ti) by plasma electrolytic oxidation (PEO) has been developed. Evaluation of osteogenerating properties of the coating at fractures of the shaft of the femur on Wistar line laboratory r...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-161608
更新日期:2016-01-01 00:00:00
abstract::In this work, we present an evolutive trabecular model for bone remodeling based on a boundary detection algorithm accounting for both biology and applied mechanical forces, known to be an important factor in bone evolution. A finite element (FE) numerical model using the Abaqus/Standard® software was used with a UMAT...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171636
更新日期:2017-01-01 00:00:00
abstract::To better analyze images with the Gaussian white noise, it is necessary to remove the noise before image processing. In this paper, we propose a self-adaptive image denoising method based on bidimensional empirical mode decomposition (BEMD). Firstly, normal probability plot confirms that 2D-IMF of Gaussian white noise...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141143
更新日期:2014-01-01 00:00:00
abstract::Polylactic acid (PLA)/styrene-ethylene-butylene-styrene (SEBS) composites were prepared by melt blending. Differential scanning calorimetry (DSC) and wide angle X-ray diffraction (WXRD) were used to characterize PLA and PLA/SEBS composites in terms of their melting behavior and crystallization. Curves from thermal gra...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151300
更新日期:2015-01-01 00:00:00
abstract::The balance between extracellular inorganic phosphate (ePi) and extracellular inorganic pyrophosphate (ePPi) is controlled by four membrane proteins: the transporters ANK (exporting PPi outside the cells) and PiT-1 (importing ePi into the cells), and the enzymes PC-1 (generating ePPi from nucleotides) and Tissue Non-s...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2010-0634
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To study the comprehensive biomechanical properties of the cancellous bone of distal femur through a series of mechanical tests, and provide relevant subjects with the basic technical data. BACKGROUND:The study on bone mechanics is a commonly used approach to evaluate the biomechanical competency of bone. Th...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Since adhesive technology was introduced into dental field, metal-based restoration has been gradually replaced by metal-free restoration. Using the adhesive technology, minimum invasive technique has been possible in daily clinical practice as well as esthetic tooth-colored restorations have become very popular all o...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:10.3233/BME-2009-0587
更新日期:2009-01-01 00:00:00
abstract::Hydroxyapatite was coated with 1 microm thickness on titanium columns of a length of 10 mm, an outer diameter of 4.0 mm by radio frequency magnetron sputtering. The hydroxyapatite coating titanium columns were implanted in the diaphysis of femora of 3 adult dogs, and push-out test was carried out after 2, 4 and 12 wee...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract:UNLABELLED:It is suggested that nanophase hydroxyapatite (nHAP) might have advantages over conventional hydroxyapatite (cHAP) as a biomaterial for bone regeneration. To be a satisfactory candidate for bone tissue engineering, it is important to support the growth and differentiation of bone marrow-derived mesenchymal s...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::A driver's response to a front-coming vehicle collision consists of braking reaction time and braking behavior. The purpose was to investigate drivers' responses at different speeds, relative distances, and particularly the behavior on the accelerator at the collision moment. Twelve young men participated in driving s...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151347
更新日期:2015-01-01 00:00:00
abstract::The bonding strength of porcelains to metals depends on the oxide layer between the porcelain and the metal. Oxidation of a metal surface increases the bonding strength, whereas excessive oxidation decreases it. Titanium and its alloys are gaining acceptance for dental use since they exhibit excellent biocompatibility...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:Normal pregnancy is associated with profound alterations in the maternal cardiovascular system and PPG represents a sensitive and convenient technique capable of tracking changes in the pulsatile function of arteries. The aim of this study was to investigate the effects of maternal cardiovascular alterations ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130801
更新日期:2014-01-01 00:00:00
abstract::This study investigates the radiation safety of a newly designed magnetic induction sensor. This novel magnetic induction sensor uses a two-arm Archimedean spiral coil (TAASC) as the exciter. A human head model with a real anatomical structure was used to calculate the specific absorption rate (SAR) and temperature ch...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151329
更新日期:2015-01-01 00:00:00
abstract::Modeling of thermal-induced mechanical behaviors of soft tissues is of great importance for thermal ablation. This paper presents a method by integrating the heating process with thermal-induced mechanical deformations of soft tissues for simulation and analysis of the thermal ablation process. This method combines bi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141043
更新日期:2014-01-01 00:00:00
abstract::In a previous work by the author [H.S. Hedia and M. Nemat-Alla, Design optimization of functionally graded dental implant, submitted to be published in the J. Bio-Medical Materials and Engineering], a functionally graded material dental implant was designed without cansellous bone in the model. In this investigation t...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To characterize the structure and to evaluate the cytotoxicity of cellulose nanowhiskers (CNW) prepared from cotton linters. METHODS:A series of CNW dispersions was prepared by hydrolyzing cotton linters with sulfuric acid. The structure of CNW was characterized by scanning electron microscopy (SEM), transmi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2012-0697
更新日期:2012-01-01 00:00:00
abstract::Longitudinal stent compression (LSC) is a new failure mode not previously observed in coronary stents. This phenomenon occurs when the physician tries to cross the deployed stent with other devices. While this phenomenon has been observed with a number of stent designs, it seems more common with the Element stent. A c...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130781
更新日期:2014-01-01 00:00:00
abstract::Sepsis is a systemic inflammatory response syndrome with high mortality, which results from severe infection and can lead to secondary organ dysfunction. It is one of the most common cause of death in intensive care unit. Clinical reports have shown that sepsis was often accompanied by thyroid dysfunction, which is ca...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:10.3233/BME-171646
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Electrospinning is a highly effective method in order to generate nano-scaled fibers. In conventional electrospinning technique, geometry of nanofibers are mostly random due to the chaotic behavior of polymer jet. OBJECTIVE:Purpose of this study is to produce aligned nanofibers from PVP polymers with advanc...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-181017
更新日期:2018-01-01 00:00:00
abstract::To build a patient specific respiratory motion model with a low dose, a novel method was proposed that uses a limited number of 3D lung CT volumes with an external respiratory signal. 4D lung CT volumes were acquired for patients with in vitro labeling on the upper abdominal surface. Meanwhile, 3D coordinates of in vi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141133
更新日期:2014-01-01 00:00:00
abstract::Dry emulsion containing curcumin (DE-CUR) was prepared for oral delivery of poorly water-soluble curcumin, and its oral bioavailability and antiasthmatic efficacy was evaluated. After comparison of the solubility of curcumin in various oils, Plurol® Oleique CC497 was selected to be the oil phase due to its higher solu...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130886
更新日期:2014-01-01 00:00:00
abstract::In this second part of the series of reviews, attention focuses on analytical and numerical methods that have been used to estimate the magnitude of the contact stress in: models of articular joints; models of total joint replacements, without and with the associated joint; or models of simple physical systems that ar...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:
更新日期:1998-01-01 00:00:00
abstract::Poly(propylene fumarate-co-ethylene glycol) random (PPF-1) and block (PPF-2) copolymer oligomers were prepared. Comparing the setting characteristics of PPF-1 and PPF-2 with comonomer n-vinyl pyrrolidone (n-VP) and swelling characteristics of cured PPF-1 and PPF-2, lower setting temperature and setting time was observ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00