In vivo study of osteogenerating properties of calcium-phosphate coating on titanium alloy Ti-6Al-4V.

Abstract:

:The method of formation of bioactive calcium-phosphate coating on medical titanium alloy Ti-6Al-4V (3.5-5.3% V; 5.3-6.8% Al; balance -Ti) by plasma electrolytic oxidation (PEO) has been developed. Evaluation of osteogenerating properties of the coating at fractures of the shaft of the femur on Wistar line laboratory rats has been performed. It has been established that the calcium-phosphate PEO coating accelerates osteogenesis and promotes the formation of a pronounced periosteal callus in the fracture area. The presence of calcium phosphates in the PEO coating surface layer significantly accelerates the growth of bone tissue on the titanium surface.

journal_name

Biomed Mater Eng

authors

Gnedenkov SV,Sinebryukhov SL,Puz AV,Egorkin VS,Kostiv RE

doi

10.3233/BME-161608

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

551-560

issue

6

eissn

0959-2989

issn

1878-3619

pii

BME1608

journal_volume

27

pub_type

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