Biocompatibility and characterization of polylactic acid/styrene-ethylene-butylene-styrene composites.

Abstract:

:Polylactic acid (PLA)/styrene-ethylene-butylene-styrene (SEBS) composites were prepared by melt blending. Differential scanning calorimetry (DSC) and wide angle X-ray diffraction (WXRD) were used to characterize PLA and PLA/SEBS composites in terms of their melting behavior and crystallization. Curves from thermal gravimetric analysis (TGA) illustrated that thermostability increased with SEBS content. Further morphological analysis of PLA/SEBS composites revealed that SEBS molecules were not miscible with PLA molecules in PLA/SEBS composites. The tensile testing for PLA and PLA/SEBS composites showed that the elongation at the break was enhanced, but tensile strength decreased with increasing SEBS content. L929 fibroblast cells were chosen to assess the cytocompatibility; the cell growth of PLA was found to decrease with increasing SEBS content. This study proposes possible reasons for these properties of PLA/SEBS composites.

journal_name

Biomed Mater Eng

authors

Tsou CH,Kao BJ,Yang MC,Suen MC,Lee YH,Chen JC,Yao WH,Lin SM,Tsou CY,Huang SH,De Guzman M,Hung WS

doi

10.3233/BME-151300

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

S147-54

eissn

0959-2989

issn

1878-3619

pii

BME1300

journal_volume

26 Suppl 1

pub_type

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