Abstract:
:DNA-binding proteins are involved and play a crucial role in a lot of important biological processes. Hence, the identification of the DNA-binding proteins is a challenging and significant problem. In order to reveal the intrinsic information correlated to DNA-binding, nine classes of candidate features based on different mathematical fields are applied to construct the prediction model with random forest. They are fractal dimension, conjoint triad feature, Hilbert-Huang Transformation, amino acid composition, dipeptide composition, chaos game representation, and the corresponding information entropies. These mathematical expressions are evaluated with 5-fold cross validation test. The results of numerical simulations show that the mathematical features consisted of amino acid composition, fractal dimension and information entropies of amino acid and chaos game representation achieve the best performance. Its accuracy is 0.8157, and Matthew's correlation coefficient (MCC) achieves 0.5968 on the benchmark dataset from DNA-Prot. By analyzing the components of top combination of the nine candidate features, the concepts of fractal dimension and information entropy are the effective and vital features, which can provide complementary sequence-order information on the basis of amino acid composition.
journal_name
Biomed Mater Engjournal_title
Bio-medical materials and engineeringauthors
Guan C,Niu X,Shi F,Yang K,Li Ndoi
10.3233/BME-151491subject
Has Abstractpub_date
2015-01-01 00:00:00pages
S1883-9eissn
0959-2989issn
1878-3619pii
BME1491journal_volume
26 Suppl 1pub_type
杂志文章abstract::Morse code is now being harnessed for use in rehabilitation applications of augmentative-alternative communication and assistive technology, including mobility, environmental control and adapted worksite access. In this paper, Morse code is selected as a communication adaptive device for disabled persons who suffer fr...
journal_title:Bio-medical materials and engineering
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Access to peripheral veins is necessary for sample collection, transfusion and infusion of fluids or medications. The peripheral intravenous catheterization (PIVC) procedure is the introduction of a short catheter into a peripheral vein and can be problematic, leading to multiple failed attempts. PURPOSE:To...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:10.3233/BME-120735
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Accelerated hydrothermal aging has long been one of the most widely accepted quality control tests for simulating low-temperature degradation (LTD) in zirconia-containing implants used in total hip arthroplasty (THA). However, it is still unclear how much consistency there is between the experimental predict...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-201083
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Adhesive resin composite, which is used to bond orthodontic bracket to tooth surface is exposed to the influence of wear by tooth brushing and wear may influence loosening of the bracket. OBJECTIVE:The aim of this study was to evaluate in vitro the effect of tooth brushing on the adhesion strength of orthod...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-161592
更新日期:2016-09-28 00:00:00
abstract::The values of the propagation coefficient measured on a silicon rubber tube in the frequency range 1-15 Hz were compared, using four different equations. The first formula is based on three simultaneous pressure measurements performed at equidistant points; the remaining three equations are original, and make use of o...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract::Local strains acting across an area of skin loaded uniaxially in vivo are converted to stresses using the standard elastic formulae. The stress values are compared to those obtained using the classical Bossinesq and Michell stress functions. The results indicate that these functions are capable of describing the respo...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Resorbable ceramics can promote the bony integration of implants. Their rate of degradation should ideally be synchronized with bone regeneration. This study examined the effect of rapidly resorbable calcium phosphate ceramics 602020, GB14, 305020 on adherence, proliferation and morphology of human bone-derived cells ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2012-0678
更新日期:2011-01-01 00:00:00
abstract::Shape memory alloys (SMA) are being increasingly used in various industrial applications as actuators, connectors, or damping materials. In the medical field, superelastic devices such as eyeglass frames, stents or guide catheters have come to market in the recent years. The design of SMA devices has usually been base...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::To build a patient specific respiratory motion model with a low dose, a novel method was proposed that uses a limited number of 3D lung CT volumes with an external respiratory signal. 4D lung CT volumes were acquired for patients with in vitro labeling on the upper abdominal surface. Meanwhile, 3D coordinates of in vi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141133
更新日期:2014-01-01 00:00:00
abstract::Hydroxyapatite is widely utilized as a component in dental hygiene agents. The ability to adsorb and remove dental plaque adhering to tooth surfaces is recognized as an important property of hydroxyapatite particles. In this study, the adsorptive ability of hydroxyapatite was evaluated based on its adsorptive amount a...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::We previously reported a simple method for the preparation of size-controlled spherical silver nanoparticles (Ag NPs) generated by autoclaving a mixture of silver-containing glass powder and glucose. The particle size is regulated by the glucose concentration, with concentrations of 0.25, 1.0 and 4.0 wt% glucose provi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130772
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Great potential of cellular therapies has generated extensive research in the field of cells harvesting and culturing. Transplantation of cell cultures has been used in a variety of therapeutic programs but in many cases it appeared that biomaterial scaffold or sheath would enhance cells regenerative potenti...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-140966
更新日期:2014-01-01 00:00:00
abstract::Bioelectrical impedance phase angle has been recommended as a tool to assess nutrition state, but there are no measuring devices have been specially designed for hospital residents. In this study, a system was established for the measurement of bioelectrical impedance phase angle. The electrical composition, calculati...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141193
更新日期:2014-01-01 00:00:00
abstract::Facial nerve paralysis is a common disease due to nerve damage. Most approaches for evaluating the degree of facial paralysis rely on a set of different facial movements as commanded by doctors. Therefore, automatic recognition of the patterns of facial movement is fundamental to the evaluation of the degree of facial...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141093
更新日期:2014-01-01 00:00:00
abstract::Since adhesive technology was introduced into dental field, metal-based restoration has been gradually replaced by metal-free restoration. Using the adhesive technology, minimum invasive technique has been possible in daily clinical practice as well as esthetic tooth-colored restorations have become very popular all o...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:10.3233/BME-2009-0587
更新日期:2009-01-01 00:00:00
abstract::Polycrystalline diamond (PCD) exhibits excellent abrasive characteristics and is commonly used as loose grains for precision machining of hard ceramics and other materials that are difficult to grind and polish. In the present study, we investigated using bonded PCD for polishing dental porcelain, for which a lustrous...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2010-0642
更新日期:2010-01-01 00:00:00
abstract::Synthetic grafting materials, such as calcium phosphates (hydroxyapatite, HA; tricalcium phosphate, TCP), polymers, or composites thereof, can be used as osteoconductive scaffolds and delivery vehicles for osteoinductive growth factors. Carrier materials must be engineered to deliver these factors in a controlled fash...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:UNLABELLED:It is suggested that nanophase hydroxyapatite (nHAP) might have advantages over conventional hydroxyapatite (cHAP) as a biomaterial for bone regeneration. To be a satisfactory candidate for bone tissue engineering, it is important to support the growth and differentiation of bone marrow-derived mesenchymal s...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Hydroxyapatite has been rubbed against ultra-high-molecular-weight-polyethylene (UHMWPE) under calcium-containg aqueous solutions. Further, hardness tests were carried out in air and in calcium-containing solutions whose pH ranged from pH 5 to pH 9. Hardness was found to vary with pH with a peak at around pH 7, i.e. -...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::The aim of this work was to investigate the effect of 2.4 MeV proton irradiation on the dielectric property of polyethylene terephthalate (PET) microfibre nondestructively. The dielectric constant εd of single-microfibre has been measured as-such applying laser diffraction technique. Applying this methodology εd is fo...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130947
更新日期:2014-01-01 00:00:00
abstract::Reoperation of aldehyde tanned bioprotheses due to calcific degeneration remains their major drawback. Based on experiments studying mechanisms and factors that influence the time phase, extent and progression of calcification and evaluating the efficiency of anticalcification treatments and the effects of surface see...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::The hip stem design based upon X-ray films requires sufficient information in order to customize for the patient. If the errors are resulted from rotating angles, more X-ray films may carry out the solution. The present study aimed to realize the improvement of multiple X-ray films for hip stem design. Eight X-ray fil...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Robotized endoscope holder in laparoscopic surgeries allows surgeons to control the endoscope without the assistants' intervention. In this paper, a new method is proposed for the automatic 3D-tracking of laparoscopic instruments in real-time to provide more convenient interactions between surgeons and the robotized e...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141083
更新日期:2014-01-01 00:00:00
abstract::The objective of the present study was to find a standard substance for use as a reference in the cytotoxicity assay of biomaterials, as an alternative to animal experiments in recent years. Eight kinds of rubber were made in a plate shape to keep their surface area at 1 cm2 against 10 ml of extract volume. They were ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:to assess reliability and reproducibility of quantitative MRI (7 T) in assessing rat femoro-tibial cartilage volume. METHODS:5 healthy rat knees were scanned in vivo using a 7 T experimental imager. Sagittal high resolution 3D Gradient Echo with fat suppression sequences were performed with a dedicated home...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::In recent years, there is an increasing utilization and demand to use magnetic fields in bioengineering applications due to its beneficial effects. Although in the last decade more attention has been given by tribologists to the electromagnetic processes taking place between sliding surfaces, which influence the tribo...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::In order to explore the effects of hydrogen sulfide (H2S) on myocardial fibrosis in diabetic rats and its underlying mechanisms, intraperitoneal injections of streptozotocin were used to establish the diabetes models and sodium hydrosulfide (NaHS) was used as an exogenous donor of H2S. Eight weeks later, Van Gieson st...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151508
更新日期:2015-01-01 00:00:00
abstract::A new training system that can adjust training intensity and indicate the center pressure of a subject was proposed by applying controlled electric current to the Magneto-Rheological damper. The experimental studying on the muscular activities were performed in lower extremities during maintaining and moving exercises...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130811
更新日期:2014-01-01 00:00:00
abstract::A multidirectional pin-on-plate reciprocating machine was used to compare the wear performance of UHMWPE sliding against cast cobalt chrome (CoCr) plates that were either untreated or coated with Amorphous Diamond Like Carbon (ADLC). The test conditions were based on a 1/5 scale model representative of in vivo motion ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Commercially pure titanium (CPT) substrate was subjected to porcelain firing and bond strengths under three-point bending mode (span length: 15 mm; crosshead speed: 0.5 mm/min) were evaluated. Experimental variables included surface treatments of CPT and porcelain firing schedules. Variables for the surface treatments...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00