Abstract：
BACKGROUND:Accelerated hydrothermal aging has long been one of the most widely accepted quality control tests for simulating low-temperature degradation (LTD) in zirconia-containing implants used in total hip arthroplasty (THA). However, it is still unclear how much consistency there is between the experimental prediction from the internationally-standardized tests and the actual measurements from surgically-removed implants after a long period of implantation. This question is fundamentally related to a lack of understanding of mechanical/tribological contribution to the in-vivo LTD kinetics. OBJECTIVE:The main purpose of this study is to validate the clinical relevance of standardized accelerated aging by comparing artificially-aged and in-vivo used prostheses, and to clarify the long-term effects of in-vivo mechanics/tribology on the LTD progression upon service in the body environment. METHODS:Surface magnitudes of phase transformation and residual stress in zirconia femoral head retrievals (13.1-18.4 yrs) were evaluated by using confocal Raman microspectroscopy. RESULTS:The long-term aging behavior in unworn head surface was in agreement with the experimental prediction estimated as 1 h aging at 134 °C = 4 years in-vivo. However, the current aging protocols based on ASTM and ISO criteria were not accurately predictive for the worn surfaces, and the tribologically-induced phase transformation and tensile stress were up to 6.5-times and 3.3-times higher than the environmentally-induced ones. CONCLUSION:Our study suggests that wear/scratching, frictional heating, tribochemical reactions, and metal transfer may become far more intense triggers to phase transformation than the mere exposure to body fluid.
journal_name
Biomed Mater Engjournal_title
Bio-medical materials and engineeringauthors
Tateiwa T,Takahashi Y,Pezzotti G,Shishido T,Masaoka T,Sano K,Yamamoto Kdoi
10.3233/BME-201083subject
Has Abstractpub_date
2020-01-01 00:00:00pages
107-117issue
2eissn
0959-2989issn
1878-3619pii
BME201083journal_volume
31pub_type
杂志文章abstract：:Level set method has been widely used in medical image analysis, but it has difficulties when being used in the segmentation of left ventricular (LV) boundaries on echocardiography images because the boundaries are not very distinguish, and the signal-to-noise ratio of echocardiography images is not very high. In this...
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abstract：:The biological, biochemical, mechanical, and structural properties of artificial scaffolds for tissue engineering are known to be of great importance. Therefore, in this study a hydrogel derived scaffold with biomechanical and structural properties similar to native articular cartilage was synthesized. The gelatine-ba...
journal_title：Bio-medical materials and engineering
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abstract：:Stroke is a major cause of death and disability throughout the world. Subtotal occlusion of the carotid artery is an important risk factor for stroke. Carotid artery stenting (CAS) is increasingly being used for treatment of carotid artery stenosis. There are many reports on treating carotid artery stenosis by CAS; ho...
journal_title：Bio-medical materials and engineering
pub_type： 杂志文章
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journal_title：Bio-medical materials and engineering
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journal_title：Bio-medical materials and engineering
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doi：10.3233/BME-130897
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journal_title：Bio-medical materials and engineering
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更新日期：2003-01-01 00:00:00
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journal_title：Bio-medical materials and engineering
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doi：
更新日期：2002-01-01 00:00:00
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journal_title：Bio-medical materials and engineering
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更新日期：2008-01-01 00:00:00
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journal_title：Bio-medical materials and engineering
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journal_title：Bio-medical materials and engineering
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更新日期：1994-01-01 00:00:00
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journal_title：Bio-medical materials and engineering
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journal_title：Bio-medical materials and engineering
pub_type： 杂志文章,评审
doi：
更新日期：2002-01-01 00:00:00
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journal_title：Bio-medical materials and engineering
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doi：10.3233/BME-2011-0653
更新日期：2011-01-01 00:00:00
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journal_title：Bio-medical materials and engineering
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更新日期：1994-01-01 00:00:00
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journal_title：Bio-medical materials and engineering
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doi：
更新日期：1998-01-01 00:00:00
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journal_title：Bio-medical materials and engineering
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journal_title：Bio-medical materials and engineering
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journal_title：Bio-medical materials and engineering
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