Abstract:
:The thrust of the present work is the demonstration of the feasibility of using an enzyme-linked immunosorbent assay (ELISA) for the detection and quantification of a monoclonal antibody human serum. The antibodies used, 7E3 and D3GP3, have been proposed as platelet receptor blockers, being directed specifically against the platelet membrane receptors (glycoprotein IIb/IIIa) and thus of significance in the management of patients at a very hgih risk of thrombotic occlusion. It is shown that 7E3 is more easily adsorbed than D3GP3 and hence has a higher potential for the stated application.
journal_name
Biomed Mater Engjournal_title
Bio-medical materials and engineeringauthors
Lewis Gsubject
Has Abstractpub_date
1994-01-01 00:00:00pages
363-7issue
5eissn
0959-2989issn
1878-3619journal_volume
4pub_type
杂志文章abstract:BACKGROUND:Age is the most important risk factor for primary osteoarthritis (OA). Members of the TGF-β superfamily play a crucial role in chondrocyte differentiation and maintenance of healthy articular cartilage. OBJECTIVE:We have investigated whether age-related changes in TGF-β superfamily signaling components play...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-140976
更新日期:2014-01-01 00:00:00
abstract::Correlation-based feature selection (CFS) using neighborhood mutual information (NMI) and particle swarm optimization (PSO) are combined into an ensemble technique in this paper. Based on this observation, an efficient gene selection algorithm, denoted by NMICFS-PSO, is proposed. Several cancer recognition tasks are g...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130897
更新日期:2014-01-01 00:00:00
abstract::Crystalline hydroxyapatite (HA) powder was coated on titanium substrate by radio frequency (RF) magnetron sputtering. The coating was homogeneous thin film and the thickness was 1microm. Crystallinity of the HA coating was low and Ca/P ratio was high as 3.0. Particle sizes were 40 to approximately 100 nm, and the crys...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Based upon previous research on the relation between hip prosthesis designs and strain distributions in a proximal femur model, a prototype of a "physiological" hip prosthesis was designed and manufactured. Strain gauge measurements on a dry femur before and after implantation of this prosthesis were made in different...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::This study aimed to determine the optimal starting material for the development of an acellular osteochondral graft. Osteochondral tissues from three different species were characterised; pig (6 months), cow (18 months) and two ages of sheep (8-12 months and >4 year old). Tissues from the acetabulum and femoral head o...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151533
更新日期:2015-01-01 00:00:00
abstract::The fretting corrosion of five materials for implant suprastructures (cast-titanium, machined-titanium, gold alloy, silver-palladium alloy and chromium-nickel alloy), was investigated in vitro, the materials being galvanically coupled to a titanium ball-and-socket-joint with tetrafluoroethylene under mechanical load. ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::A multidirectional pin-on-plate reciprocating machine was used to compare the wear performance of UHMWPE sliding against cast cobalt chrome (CoCr) plates that were either untreated or coated with Amorphous Diamond Like Carbon (ADLC). The test conditions were based on a 1/5 scale model representative of in vivo motion ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::In this paper, a new method for individual tooth segmentation was proposed. The proposed method is composed of enhancement and extraction of boundary and seed of watershed algorithm using trisection areas by morphological characteristic of teeth. The watershed algorithm is one of the conventional methods for tooth seg...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141153
更新日期:2014-01-01 00:00:00
abstract::The aim of this study was to assess the characteristics of the CaP/Col composites, in powder and fiber form, via scanning electron microscopy (SEM), pH and calcium release evaluation after immersion in SBF and to evaluate the performance of these materials on the bone repair process in a tibial bone defect model. For ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-161581
更新日期:2016-08-12 00:00:00
abstract::Shape memory alloys (SMA) are being increasingly used in various industrial applications as actuators, connectors, or damping materials. In the medical field, superelastic devices such as eyeglass frames, stents or guide catheters have come to market in the recent years. The design of SMA devices has usually been base...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Biocompatible metals have been suggested as revolutionary biomaterials for bone-grafting therapies. Although metals and their alloys are widely and successfully used in producing biomedical implants due to their good mechanical properties and corrosion resistance, they have a lack in bioactivity. Therefore coating of ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:10.3233/BME-161568
更新日期:2016-05-12 00:00:00
abstract:OBJECTIVES:to assess reliability and reproducibility of quantitative MRI (7 T) in assessing rat femoro-tibial cartilage volume. METHODS:5 healthy rat knees were scanned in vivo using a 7 T experimental imager. Sagittal high resolution 3D Gradient Echo with fat suppression sequences were performed with a dedicated home...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:We aimed to develop a novel ultrasound system and examine its feasibility for noninvasively detecting thoracic aortic aneurysm (TAA) in clinical settings. METHODS:We developed a novel ultrasound system consisting of a modified console and data analysis algorithm. The exploratory study included 100 patients h...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-191047
更新日期:2019-01-01 00:00:00
abstract::Level set method has been widely used in medical image analysis, but it has difficulties when being used in the segmentation of left ventricular (LV) boundaries on echocardiography images because the boundaries are not very distinguish, and the signal-to-noise ratio of echocardiography images is not very high. In this...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151427
更新日期:2015-01-01 00:00:00
abstract::Morse code is now being harnessed for use in rehabilitation applications of augmentative-alternative communication and assistive technology, including mobility, environmental control and adapted worksite access. In this paper, Morse code is selected as a communication adaptive device for disabled persons who suffer fr...
journal_title:Bio-medical materials and engineering
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Mechanical testing has been performed to characterize the locking strength of Morse taper locks used for reconstruction of large bone defects. Taper joint pairs were locked with a series of compressive loads increasing from 500 to 3500 N. Following each load application the taper locks were distracted with either an a...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:UNLABELLED:It is suggested that nanophase hydroxyapatite (nHAP) might have advantages over conventional hydroxyapatite (cHAP) as a biomaterial for bone regeneration. To be a satisfactory candidate for bone tissue engineering, it is important to support the growth and differentiation of bone marrow-derived mesenchymal s...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Longitudinal stent compression (LSC) is a new failure mode not previously observed in coronary stents. This phenomenon occurs when the physician tries to cross the deployed stent with other devices. While this phenomenon has been observed with a number of stent designs, it seems more common with the Element stent. A c...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130781
更新日期:2014-01-01 00:00:00
abstract::To select tag single nucleotide polymorphisms (SNPs) within and around human p75 neurotrophin receptor (p75NTR) gene in Chinese Han population, the sequence involving p75NTR gene as well as the upstream and downstream of the gene was identified according to the data from National Center for Biotechnology Information (...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141213
更新日期:2014-01-01 00:00:00
abstract::Dry emulsion containing curcumin (DE-CUR) was prepared for oral delivery of poorly water-soluble curcumin, and its oral bioavailability and antiasthmatic efficacy was evaluated. After comparison of the solubility of curcumin in various oils, Plurol® Oleique CC497 was selected to be the oil phase due to its higher solu...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130886
更新日期:2014-01-01 00:00:00
abstract::This study presents a novel spatial registration method of Image-guided neurosurgery system (IGNS) based on stereo-vision. Images of the patient's head are captured by a video camera, which is calibrated and tracked by an optical tracking system. Then, a set of sparse facial data points are reconstructed from them by ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151391
更新日期:2015-01-01 00:00:00
abstract::DNA-binding proteins are involved and play a crucial role in a lot of important biological processes. Hence, the identification of the DNA-binding proteins is a challenging and significant problem. In order to reveal the intrinsic information correlated to DNA-binding, nine classes of candidate features based on diffe...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151491
更新日期:2015-01-01 00:00:00
abstract::Surface roughness has been considered as an important influencing factor for cell response. The aim of this study was to find out whether MC3T3-E1 cells, a mouse osteoblast-like cell line, can sense the amplitudes of surface topography of titanium alloy (Ti6Al4V), and if surface-dependent cell morphology would be pres...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151301
更新日期:2015-01-01 00:00:00
abstract::To address the lack of 3D space information in the digital radiography of a patient femur, a pose estimation method based on 2D-3D rigid registration is proposed in this study. The method uses two digital radiography images to realize the preoperative 3D visualization of a fractured femur. Compared with the pure Digit...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141103
更新日期:2014-01-01 00:00:00
abstract::The method used in this paper is developed to estimate the degree of viscoelasticity of the blood vessel wall in a noninvasive mechanical method. In this proposed method, we can obtain an output waveform connected with mechanical behavior of blood vessels by using Ultrasonic Doppler Effect Sensory (UDES). Characterizi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Electroencephalograph (EEG) signals feature extraction and processing is one of the most difficult and important part in the brain-computer interface (BCI) research field. EEG signals are generally unstable, complex and have low signal-noise ratio, which is difficult to be analyzed and processed. To solve this problem...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141113
更新日期:2014-01-01 00:00:00
abstract::The finite element (FE) method has been widely used to investigate the mechanism of traumatic brain injuries (TBIs), because it is technically difficult to quantify the responses of the brain tissues to the impact in experiments. One of technical challenges to build a FE model of a human head is the modeling of the ce...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171666
更新日期:2017-01-01 00:00:00
abstract::Currently, clinicians face choices of restoration including amalgams (mercury-based, gallium-based alloys, or mercury-free silver-based substitutes), composite resins, ceramics, and gold alloy. In order to choose an appropriate restorative material, many parameters are involved; they include preparation time requireme...
journal_title:Bio-medical materials and engineering
pub_type: 历史文章,杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::Wearable robotic devices provide safe and intensive rehabilitation, enabling repeated motions for motor function recovery in stroke patients. The aim of this small case series was to demonstrate the training effects of a three-week robotic leg orthosis, and to investigate possible mechanisms of the sensory-motor alter...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151320
更新日期:2015-01-01 00:00:00
abstract::Reoperation of aldehyde tanned bioprotheses due to calcific degeneration remains their major drawback. Based on experiments studying mechanisms and factors that influence the time phase, extent and progression of calcification and evaluating the efficiency of anticalcification treatments and the effects of surface see...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00