Abstract:
:Surface roughness has been considered as an important influencing factor for cell response. The aim of this study was to find out whether MC3T3-E1 cells, a mouse osteoblast-like cell line, can sense the amplitudes of surface topography of titanium alloy (Ti6Al4V), and if surface-dependent cell morphology would be presented on the substrata with varied roughness. A series of polished samples (Ra: 0.30~1.80 μm) were prepared to produce macroscopically parallel grooves using different grades of silicon carbide sandpaper (#100, #320, #600, #1000 and #2000). The experimental results indicated that the behavior and morphology of cells largely depended on the substrata where they were cultured. More efficient proliferation of MC3T3-E1 cells was shown on the surfaces with Ra of 0.50~1.00 μm, with respect to either the rougher or the smoother specimens. Furthermore, MC3T3-E1 cells seeded on the Ti6Al4V surfaces within this narrow range responded to the increasing surface roughness with increased proliferation. Contact guidance of cells could be observed on the rougher specimens (Ra: 0.80~1.00 μm), whereas more random orientations were exhibited for the adsorbed cells on the smoother surfaces (Ra: 0.50~0.60 μm).
journal_name
Biomed Mater Engjournal_title
Bio-medical materials and engineeringauthors
Wu C,Chen M,Zheng T,Yang Xdoi
10.3233/BME-151301subject
Has Abstractpub_date
2015-01-01 00:00:00pages
S155-64eissn
0959-2989issn
1878-3619pii
BME1301journal_volume
26 Suppl 1pub_type
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
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journal_title:Bio-medical materials and engineering
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doi:10.3233/BME-130781
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-181019
更新日期:2018-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171626
更新日期:2017-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151300
更新日期:2015-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,随机对照试验
doi:10.3233/BME-151517
更新日期:2015-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::To address the lack of 3D space information in the digital radiography of a patient femur, a pose estimation method based on 2D-3D rigid registration is proposed in this study. The method uses two digital radiography images to realize the preoperative 3D visualization of a fractured femur. Compared with the pure Digit...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141103
更新日期:2014-01-01 00:00:00
abstract::Using a wet method, we have synthesized octacalcium phosphate carbonate, in which HPO42- in octacalcium phosphate is replaced with CO32-. The physical, crystal, and chemical properties of this new material were compared to octacalcium phosphate, Ca-deficient hydroxyapatite, and Ca-deficient carbonate apatite using X-r...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171651
更新日期:2017-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130843
更新日期:2014-01-01 00:00:00
abstract::Dry emulsion containing curcumin (DE-CUR) was prepared for oral delivery of poorly water-soluble curcumin, and its oral bioavailability and antiasthmatic efficacy was evaluated. After comparison of the solubility of curcumin in various oils, Plurol® Oleique CC497 was selected to be the oil phase due to its higher solu...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130886
更新日期:2014-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141073
更新日期:2014-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2011-0653
更新日期:2011-01-01 00:00:00
abstract::In order to investigate the significance of hydroxyapatite based microporous composite (HA/mica composite) surfaces and a macroporous synthetic hydroxyapatite, rat marrow cell culture, which shows osteogenic differentiation, was carried out on six different culture substrata (two control culture dishes, two identical ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Age is the most important risk factor for primary osteoarthritis (OA). Members of the TGF-β superfamily play a crucial role in chondrocyte differentiation and maintenance of healthy articular cartilage. OBJECTIVE:We have investigated whether age-related changes in TGF-β superfamily signaling components play...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-140976
更新日期:2014-01-01 00:00:00
abstract::The values of the propagation coefficient measured on a silicon rubber tube in the frequency range 1-15 Hz were compared, using four different equations. The first formula is based on three simultaneous pressure measurements performed at equidistant points; the remaining three equations are original, and make use of o...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171719
更新日期:2018-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141183
更新日期:2014-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2009-0598
更新日期:2009-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2011-0671
更新日期:2011-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151427
更新日期:2015-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The method of formation of bioactive calcium-phosphate coating on medical titanium alloy Ti-6Al-4V (3.5-5.3% V; 5.3-6.8% Al; balance -Ti) by plasma electrolytic oxidation (PEO) has been developed. Evaluation of osteogenerating properties of the coating at fractures of the shaft of the femur on Wistar line laboratory r...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-161608
更新日期:2016-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141173
更新日期:2014-01-01 00:00:00