Abstract:
:Two different types of colloidal lipid particles are presented and compared as innovative carrier systems. Size distribution and storage stability of formulations produced by hot high pressure homogenisation in lab and medium scale production were investigated by laser diffractometry (LD) and photon correlation spectroscopy (PCS). Nanoparticles were characterised by their melting and recrystallisation behaviour recorded by differential scanning calorimetry (DSC). Electron microscope investigations were also carried out showing the particulate character of these carriers. Reasons for observed differences in loading capacity are discussed and possibilities for dermal application are described.
journal_name
Biomed Mater Engjournal_title
Bio-medical materials and engineeringauthors
Saupe A,Wissing SA,Lenk A,Schmidt C,Müller RHsubject
Has Abstractpub_date
2005-01-01 00:00:00pages
393-402issue
5eissn
0959-2989issn
1878-3619journal_volume
15pub_type
杂志文章abstract:OBJECTIVE:Normal pregnancy is associated with profound alterations in the maternal cardiovascular system and PPG represents a sensitive and convenient technique capable of tracking changes in the pulsatile function of arteries. The aim of this study was to investigate the effects of maternal cardiovascular alterations ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130801
更新日期:2014-01-01 00:00:00
abstract::Metal patch test is often used in clinical settings when metal-induced contact dermatitis is suspected. However, the transdermal permeation behavior of metal ions from the patch test remains unclear. Current patch tests using high concentrations of metal salt solutions have some side effects, e.g. acute skin reactions...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151543
更新日期:2015-01-01 00:00:00
abstract::To address the lack of 3D space information in the digital radiography of a patient femur, a pose estimation method based on 2D-3D rigid registration is proposed in this study. The method uses two digital radiography images to realize the preoperative 3D visualization of a fractured femur. Compared with the pure Digit...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141103
更新日期:2014-01-01 00:00:00
abstract::The debris generated by the progressive wear of total joint replacement (TJR) devices is considered a primary cause of osteolysis, bone resorption, and premature failure of artificial hips and knees. The vast majority of this debris originates from the UHMWPE articulating surfaces caused by tribological interaction wi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::To evaluate the deterioration in the superelasticity of Ti-coated NiTi orthodontic wires, titanium was coated onto wires to form a 1-microm thick film using radio frequency magnetron sputtering. In superelasticity cycle tests, the sigma5.0 value (the stress at 5.0% strain) of a Ti-coated wire was lower than that of a ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::Magnesium has attracted a lot of attention as a new class of biodegradable material. The surface properties of magnesium in simulated body fluid (SBF) were investigated in the current research work. Cast magnesium samples with different surface characteristics were prepared which were then placed in SBF for 2, 4 and 8...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-191057
更新日期:2019-01-01 00:00:00
abstract::The goal of the study was to determine material constants of cancellous tissue in a compression test taking into account stress-strain characteristics. The nineteen test samples were resected from a femoral head of a patient qualified for a hip replacement surgery. During the compression tests, load-displacement curve...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-180999
更新日期:2018-01-01 00:00:00
abstract::Since adhesive technology was introduced into dental field, metal-based restoration has been gradually replaced by metal-free restoration. Using the adhesive technology, minimum invasive technique has been possible in daily clinical practice as well as esthetic tooth-colored restorations have become very popular all o...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:10.3233/BME-2009-0587
更新日期:2009-01-01 00:00:00
abstract:UNLABELLED:It is suggested that nanophase hydroxyapatite (nHAP) might have advantages over conventional hydroxyapatite (cHAP) as a biomaterial for bone regeneration. To be a satisfactory candidate for bone tissue engineering, it is important to support the growth and differentiation of bone marrow-derived mesenchymal s...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To characterize the structure and to evaluate the cytotoxicity of cellulose nanowhiskers (CNW) prepared from cotton linters. METHODS:A series of CNW dispersions was prepared by hydrolyzing cotton linters with sulfuric acid. The structure of CNW was characterized by scanning electron microscopy (SEM), transmi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2012-0697
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Platelet-rich plasma (PRP) has been used to solubilize freeze-dried chitosan (CS) formulations to form injectable implants for tissue repair. OBJECTIVE:To determine whether the in vitro performance of the formulations depends on the type of PRP preparation used to solubilize CS. METHODS:Formulations contai...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-191058
更新日期:2019-01-01 00:00:00
abstract::Dry emulsion containing curcumin (DE-CUR) was prepared for oral delivery of poorly water-soluble curcumin, and its oral bioavailability and antiasthmatic efficacy was evaluated. After comparison of the solubility of curcumin in various oils, Plurol® Oleique CC497 was selected to be the oil phase due to its higher solu...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130886
更新日期:2014-01-01 00:00:00
abstract::Morse code is now being harnessed for use in rehabilitation applications of augmentative-alternative communication and assistive technology, including mobility, environmental control and adapted worksite access. In this paper, Morse code is selected as a communication adaptive device for disabled persons who suffer fr...
journal_title:Bio-medical materials and engineering
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::DMPC and DSPC liposomes were prepared via thin film hydration method followed by sonication. Propranolol solution was incorporated into liposomes at hydration stage. TEM images showed the sizes of DSPC and DMPC were around 88 and 137 nm, respectively. The highest encapsulation ratio of propranolol was approximately 70...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-140997
更新日期:2014-01-01 00:00:00
abstract::Low-dose computed tomography reconstruction is an important issue in the medical imaging domain. Sparse-view has been widely studied as a potential strategy. Compressed sensing (CS) method has shown great potential to reconstruct high-quality CT images from sparse-view projection data. Nonetheless, low-contrast struct...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151437
更新日期:2015-01-01 00:00:00
abstract::The selection of best material pair in the hip prosthetics design for improved performance and life relies on the estimation of hip joint contact stresses and contact pressure distribution during various dynamic loading cycles: Climbing Upstairs, Climbing downstairs and Knee bending. The maximum Von Mises stress, cont...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-181019
更新日期:2018-01-01 00:00:00
abstract::Bioelectrical impedance phase angle has been recommended as a tool to assess nutrition state, but there are no measuring devices have been specially designed for hospital residents. In this study, a system was established for the measurement of bioelectrical impedance phase angle. The electrical composition, calculati...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141193
更新日期:2014-01-01 00:00:00
abstract::A crucial role during the implementation of volume visualization is to identify the optimal transfer function, since the vital information and structure can be highlighted and revealed. The boundary of the volume is shared by respective portion of the two materials formed out of it, which causes undesirable thickening...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141123
更新日期:2014-01-01 00:00:00
abstract::The aim of this study is to verify the effect of indoor horse riding exercise on basal physical exercise and lumbar muscular function. The subjects included were 20 healthy females, who participated in the horse riding exercise using SRider (Rider Co. & ChonbuK National Univ, Korea) for 30 minutes per day, 3 days per ...
journal_title:Bio-medical materials and engineering
pub_type: 临床试验,杂志文章
doi:10.3233/BME-141053
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Introduction of a new generation of artificial ligaments for ACL reconstruction, the Ligament Augmentation and Reconstruction System (LARS), gives promising clinical results [1]. The current literature supports the use of LARS from short to medium term. To go even further to improve the biocompatibility of t...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130753
更新日期:2013-01-01 00:00:00
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journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-206007
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Previously we found that a group of phosphorylated proteins (SIBLINGs) in bone binds with the Ti-device, and increases the early bone formation around the Ti-implants remarkably. From these results, we explained the biochemical mechanism of a strong bond between living bone and Ti, which was discovered by Br...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-201079
更新日期:2020-01-01 00:00:00
abstract::Skilled behavior is difficult or impossible to articulate explicitly by the performers. Likewise biomechanical models of skilled motor actions are often limited by the lack of knowledge of the underlying mechanisms. A 'behavioral cloning' technique is described, based on a trained artificial neural network (ANN), that...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::In this work, we present an evolutive trabecular model for bone remodeling based on a boundary detection algorithm accounting for both biology and applied mechanical forces, known to be an important factor in bone evolution. A finite element (FE) numerical model using the Abaqus/Standard® software was used with a UMAT...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171636
更新日期:2017-01-01 00:00:00
abstract::A potassium-doped synthetic apatite was prepared by soaking hydroxyapatite in potassium carbonate and potassium chloride solutions. The hydroxyapatite was prepared by firing slip cast ceramic bodies in vacuum at 1100 degrees C. The conical ceramic samples and a crushed material of this were soaked in carbonate and chl...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::In order to explore the effects of hydrogen sulfide (H2S) on myocardial fibrosis in diabetic rats and its underlying mechanisms, intraperitoneal injections of streptozotocin were used to establish the diabetes models and sodium hydrosulfide (NaHS) was used as an exogenous donor of H2S. Eight weeks later, Van Gieson st...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151508
更新日期:2015-01-01 00:00:00
abstract::Longitudinal stent compression (LSC) is a new failure mode not previously observed in coronary stents. This phenomenon occurs when the physician tries to cross the deployed stent with other devices. While this phenomenon has been observed with a number of stent designs, it seems more common with the Element stent. A c...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130781
更新日期:2014-01-01 00:00:00
abstract::Mesenchymal stem cells (MSCs) are a common tool in regenerative medicine. The nanoscale extracellular vesicles (nEVs) secreted by these cells were recently brought up to light thanks to their therapeutic potential. In this study, we assessed the in vitro behaviour of human umbilical vein endothelial cells (HUVECs) exp...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171626
更新日期:2017-01-01 00:00:00
abstract::Mechanical testing has been performed to characterize the locking strength of Morse taper locks used for reconstruction of large bone defects. Taper joint pairs were locked with a series of compressive loads increasing from 500 to 3500 N. Following each load application the taper locks were distracted with either an a...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Wearable robotic devices provide safe and intensive rehabilitation, enabling repeated motions for motor function recovery in stroke patients. The aim of this small case series was to demonstrate the training effects of a three-week robotic leg orthosis, and to investigate possible mechanisms of the sensory-motor alter...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151320
更新日期:2015-01-01 00:00:00