Abstract:
:Recognition of lung cancer cells is very important to the clinical diagnosis of lung cancer. In this paper we present a novel method to extract the structure characteristics of lung cancer cells and automatically recognize their types. Firstly soft mathematical morphology methods are used to enhance the grayscale image, to improve the definition of images, and to eliminate most of disturbance, noise and information of subordinate images, so the contour of target lung cancer cell and biological shape characteristic parameters can be extracted accurately. Then the minimum distance classifier is introduced to realize the automatic recognition of different types of lung cancer cells. A software system named "CANCER.LUNG" is established to demonstrate the efficiency of this method. The clinical experiments show that this method can accurately and objectively recognize the type of lung cancer cells, which can significantly improve the pathology research on the pathological changes of lung cancer and clinical assistant diagnoses.
journal_name
Biomed Mater Engjournal_title
Bio-medical materials and engineeringauthors
Chen YC,Hu KH,Li FZ,Li SY,Su WF,Huang ZY,Hu YXsubject
Has Abstractpub_date
2006-01-01 00:00:00pages
119-28issue
2eissn
0959-2989issn
1878-3619journal_volume
16pub_type
杂志文章abstract::In this study, a computer-aided detection (CAD) system was developed for the detection of lung nodules in computed tomography images. The CAD system consists of four phases, including two-dimensional and three-dimensional preprocessing phases. In the feature extraction phase, four different groups of features are extr...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151418
更新日期:2015-01-01 00:00:00
abstract::Two different types of colloidal lipid particles are presented and compared as innovative carrier systems. Size distribution and storage stability of formulations produced by hot high pressure homogenisation in lab and medium scale production were investigated by laser diffractometry (LD) and photon correlation spectr...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::The properties of blood flow in the outflow cannula of an axial blood pump play a critical role in potential thrombus formation and vascular injury. In this study, an in vitro flow visualization technique using particle image velocimetry (PIV) was applied to investigate the flow characteristics in the outflow cannula ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130791
更新日期:2014-01-01 00:00:00
abstract::The aim of this study is to verify the effect of indoor horse riding exercise on basal physical exercise and lumbar muscular function. The subjects included were 20 healthy females, who participated in the horse riding exercise using SRider (Rider Co. & ChonbuK National Univ, Korea) for 30 minutes per day, 3 days per ...
journal_title:Bio-medical materials and engineering
pub_type: 临床试验,杂志文章
doi:10.3233/BME-141053
更新日期:2014-01-01 00:00:00
abstract::The balance between extracellular inorganic phosphate (ePi) and extracellular inorganic pyrophosphate (ePPi) is controlled by four membrane proteins: the transporters ANK (exporting PPi outside the cells) and PiT-1 (importing ePi into the cells), and the enzymes PC-1 (generating ePPi from nucleotides) and Tissue Non-s...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-2010-0634
更新日期:2010-01-01 00:00:00
abstract::Using a wet method, we have synthesized octacalcium phosphate carbonate, in which HPO42- in octacalcium phosphate is replaced with CO32-. The physical, crystal, and chemical properties of this new material were compared to octacalcium phosphate, Ca-deficient hydroxyapatite, and Ca-deficient carbonate apatite using X-r...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171651
更新日期:2017-01-01 00:00:00
abstract::This paper explores mouse kidney imaging with diffraction enhanced imaging (DEI) and inline outline X-ray imaging (IOXI) technology, and evaluates latent value of kidney imaging with phase contrast imaging technology. In our experiment, spatial resolution and tissue contrast serve as element evaluation and comparison....
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130917
更新日期:2014-01-01 00:00:00
abstract::The present review surveys studies on physical-chemical properties and biological response of living tissues to NiTi (Nitinol) carried out recently, aiming at an understanding of the place of this material among the implant alloys in use. Advantages of shape memory and superelasticity are analyzed in respect to functi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract::Poly(N-substituted alpha/beta-asparagine) was evaluated as a thermoresponsible and an injectable scaffold for cartilage regeneration. Solutions of this polymer are liquid state below 25 degrees C and nonfluid hydrogel above 35 degrees C, allowing an aqueous solution containing cells at room temperature to form a hydro...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::In order to explore the effects of hydrogen sulfide (H2S) on myocardial fibrosis in diabetic rats and its underlying mechanisms, intraperitoneal injections of streptozotocin were used to establish the diabetes models and sodium hydrosulfide (NaHS) was used as an exogenous donor of H2S. Eight weeks later, Van Gieson st...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151508
更新日期:2015-01-01 00:00:00
abstract::The frequent occurrence of breast cancer and its serious consequences have attracted worldwide attention in recent years. Problems such as low rate of accuracy and poor self-adaptability still exist in traditional diagnosis. In order to solve these problems, an AdaBoost-SVM classification algorithm, combined with the ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141163
更新日期:2014-01-01 00:00:00
abstract::Based upon previous research on the relation between hip prosthesis designs and strain distributions in a proximal femur model, a prototype of a "physiological" hip prosthesis was designed and manufactured. Strain gauge measurements on a dry femur before and after implantation of this prosthesis were made in different...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Age-related macular degeneration (ARMD) and intraocular neovascular diseases have been treated clinically by anti-VEGF antibody drug bevacizumab. However, the use of bevacizumab in the treatment of retinal neovascular diseases has been limited due to the short half-life and frequent injections. In this research, novel...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-141003
更新日期:2014-01-01 00:00:00
abstract::The biological, biochemical, mechanical, and structural properties of artificial scaffolds for tissue engineering are known to be of great importance. Therefore, in this study a hydrogel derived scaffold with biomechanical and structural properties similar to native articular cartilage was synthesized. The gelatine-ba...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Magnesium has attracted a lot of attention as a new class of biodegradable material. The surface properties of magnesium in simulated body fluid (SBF) were investigated in the current research work. Cast magnesium samples with different surface characteristics were prepared which were then placed in SBF for 2, 4 and 8...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-191057
更新日期:2019-01-01 00:00:00
abstract::The finite element (FE) method has been widely used to investigate the mechanism of traumatic brain injuries (TBIs), because it is technically difficult to quantify the responses of the brain tissues to the impact in experiments. One of technical challenges to build a FE model of a human head is the modeling of the ce...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-171666
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The most common cause of coronary artery disease (CAD) is vascular damage with the cholesterol built-up and other materials on the inner arterial wall, known as atherosclerosis. OBJECTIVE:This paper aims to investigate the effect of stenosis on the hemodynamics in the four suspected coronary artery disease ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-191067
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Surface replication is a nondestructive evaluation technique applied in examining surface wear by recording surface irregularities, especially in conditions when surfaces of interest cannot be further manipulated to fit directly under a microscope to be examined. Enamel is the outermost protective layer of t...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-206006
更新日期:2020-01-01 00:00:00
abstract::The aim of this study was to assess the characteristics of the CaP/Col composites, in powder and fiber form, via scanning electron microscopy (SEM), pH and calcium release evaluation after immersion in SBF and to evaluate the performance of these materials on the bone repair process in a tibial bone defect model. For ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-161581
更新日期:2016-08-12 00:00:00
abstract::The objective of the present study was to find a standard substance for use as a reference in the cytotoxicity assay of biomaterials, as an alternative to animal experiments in recent years. Eight kinds of rubber were made in a plate shape to keep their surface area at 1 cm2 against 10 ml of extract volume. They were ...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Correlation-based feature selection (CFS) using neighborhood mutual information (NMI) and particle swarm optimization (PSO) are combined into an ensemble technique in this paper. Based on this observation, an efficient gene selection algorithm, denoted by NMICFS-PSO, is proposed. Several cancer recognition tasks are g...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130897
更新日期:2014-01-01 00:00:00
abstract::To evaluate the influence of Zn on the formation of hydroxyapatite (HA), zinc-containing glass 58S4Z was prepared by substitution of CaO with 4 wt% ZnO in 58S bioactive glass, and Zn-containing simulated body fluid (ZnSBF) was prepared as soaking fluid. During the soaking, all samples could induce the deposition of HA...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::The aim of the present study was to determine the degradability of aliphatic polyurethanes, based on a different amount of synthetic, atactic poly[(R,S)-3-hydroxybutyrate] (a-PHB), in hydrolytic (phosphate buffer) and oxidative (H2O2/CoCl2) solutions. The soft segments were built with atactic poly[(R,S)-3-hydroxybutyr...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-151262
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Access to peripheral veins is necessary for sample collection, transfusion and infusion of fluids or medications. The peripheral intravenous catheterization (PIVC) procedure is the introduction of a short catheter into a peripheral vein and can be problematic, leading to multiple failed attempts. PURPOSE:To...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章,评审
doi:10.3233/BME-120735
更新日期:2013-01-01 00:00:00
abstract::Hydroxyapatite is widely utilized as a component in dental hygiene agents. The ability to adsorb and remove dental plaque adhering to tooth surfaces is recognized as an important property of hydroxyapatite particles. In this study, the adsorptive ability of hydroxyapatite was evaluated based on its adsorptive amount a...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::The selection of best material pair in the hip prosthetics design for improved performance and life relies on the estimation of hip joint contact stresses and contact pressure distribution during various dynamic loading cycles: Climbing Upstairs, Climbing downstairs and Knee bending. The maximum Von Mises stress, cont...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-181019
更新日期:2018-01-01 00:00:00
abstract::The aim of this study is to design a statistical segmentation technique to allow extraction of grey matter, white matter and cerebral spinal fluid volumes from diffusion tensor imaging. Four channel maps of the DTI are used as the input features, which provide more information for brain tissue segmentation compared wi...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-130927
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Scallop shell powder is called bioshell calcium oxide (BiSCaO), which is known to possess deodorizing properties and broad antimicrobial activity against various pathogenic microbes, including viruses, bacteria, spores, and fungi. OBJECTIVE:This study aims to investigate the applications of BiSCaO suspensio...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-201082
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:We aimed to develop a novel ultrasound system and examine its feasibility for noninvasively detecting thoracic aortic aneurysm (TAA) in clinical settings. METHODS:We developed a novel ultrasound system consisting of a modified console and data analysis algorithm. The exploratory study included 100 patients h...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-191047
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Accelerated hydrothermal aging has long been one of the most widely accepted quality control tests for simulating low-temperature degradation (LTD) in zirconia-containing implants used in total hip arthroplasty (THA). However, it is still unclear how much consistency there is between the experimental predict...
journal_title:Bio-medical materials and engineering
pub_type: 杂志文章
doi:10.3233/BME-201083
更新日期:2020-01-01 00:00:00