Abstract:
:to be more frequent among patients with metabolic syndrome. Previous studies have suggested to perform a routine screening for CS in obese patients; however, more recent reports only recommend a case-finding approach in patients with uncontrolled diabetes and hypertension, despite appropriate treatment. Objective: The aim of this study was to evaluate the prevalence of unsuspected CS in morbidly obese patients in an outpatient’s clinic. Patients and methods: Retrospective case-note study. We reviewed the medical records of morbidly obese patients referred to our clinic prior to bariatric surgery between january 2001 and december 2011. All patients had a complete medical history including physical examination, and 399 underwent screening for CS as part of our pre-surgical protocol. As screening for autonomous cortisol secretion, we performed an overnight 1 mg Dexamethasone Suppression Test (DST). Serum cortisol < 1.8 μg/dl was the cut-off point for normal suppression. Results: 399 patients (308 female; mean age 41.9 ± 10.5 years; mean BMI 51.5 ± 8.4 kg/m2). In the retrospective analysis, prediabetes and diabetes mellitus were observed in 10.3% and 27.8% respectively. In 21 of 399 patients, screening was considered to be abnormal. Eight of these 21 patients had subsequent normal 24h Urinary Free Cortisol (UFC) levels (150 μg/24h). In 13 of 20 patients, we repeated an overnight 1mg DST, on suspicion of failing to take the dexamethasone correctly. Three patients failed to suppress their cortisol levels, two of them were on carbamazepine, which was considered to be a false positive result. The other patient with abnormal UFC levels was diagnosed with CS (0.26%), whose cause was a pituitary microadenoma. Conclusion: A low proportion of patients with morbid obesity were found to have CS. Our findings suggest that morbidly obese patients should not be routinely screened for CS. :Introducción: El síndrome de Cushing (SC) es más frecuente en pacientes con síndrome metabólico. Estudios previos han sugerido que es necesario realizar un despistaje de SC en pacientes obesos; sin embargo, estudios más recientes sólo recomiendan el despistaje en pacientes con hipertensión o diabetes mal controlados, a pesar de tratamiento. Objetivo: Evaluar la prevalencia de SC oculto en pacientes con obesidad mórbida. Pacientes y métodos: Estudio observacional retrospectivo en el que se incluyeron 399 pacientes que iban a someterse a cirugía bariátrica. A todos los pacientes se les realizó una historia clínica completa, incluyendo exploración física y test de Nugent, como parte del protocolo precirugía. Resultados: 399 pacientes (308 mujeres, edad media 41,9 ± 10,5 años; IMC medio 51,5 ± 8,4 kg/m2). El 10,3% de los pacientes presentaban prediabetes y el 27,8% diabetes. En 21 de los 399 pacientes, el despistaje fue anormal. En 8 pacientes, medimos cortisol libre en orina de 24 horas (CLU), siendo en todos normal al menos en dos ocasiones (CLU < 150 mcg/24 h), lo que descartaba SC. En 13 pacientes, repetimos el test de Nugent; sólo en 3, el test resultó patológico. Dos de los pacientes estaban en tratamiento con carbamacepina, lo que se consideró un falso positivo. El otro paciente se diagnosticó de Enfermedad de Cushing. Conclusión: La prevalencia de SC fue muy baja en pacientes con obesidad mórbida. Nuestros datos sugieren que no se debería realizarse un despistaje de SC de forma rutinaria.
journal_name
Nutr Hospjournal_title
Nutricion hospitalariaauthors
Alhambra Expósito MR,Tenorio Jiménez C,Molina Puerta MJ,Manzano García G,Prior Sánchez I,Muñoz Jiménez C,Gálvez Moreno MÁdoi
10.3305/nh.2014.29.5.7256subject
Has Abstractpub_date
2014-05-01 00:00:00pages
1020-3issue
5eissn
0212-1611issn
1699-5198journal_volume
29pub_type
杂志文章abstract::Percutaneous endoscopic gastrostomy (PEG) is the first choice method for long-term enteral feeding when the digestive tube is undamaged and the patients' survival is longer than 2 months. There are increasing series and indications reported and although it is a safe technique we should take into account an appropriate...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.1590/S0212-16112011000200023
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine associations between abdominal obesity (AOb) and the other components of metabolic syndrome (MetS) in young Mexicans in a cross-sectional survey completed during a 4 year period. METHODS:This cross-sectional study reports on components and prevalence of MetS by us...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.171
更新日期:2017-03-30 00:00:00
abstract::Objetivo: analizar la concordancia de dos métodos de medición (Google MapsTM vs. Sistema de Información Geográfica) para la determinación de la distancia desde el domicilio familiar hasta el colegio.Métodos: un total de 542 escolares de entre 8-11 años de edad (media = 9,36 ± 0,6) del sur de España participaron en el ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.283
更新日期:2016-06-30 00:00:00
abstract:INTRODUCTION:Health education is one of the primary tools for health promotion, especially for those that will be responsible for educating on healthy habits in the future. OBJECTIVE:To improve healthy lifestyle habits in university students through an educational intervention based on gamification. METHOD:A cuasiexp...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.669
更新日期:2017-07-28 00:00:00
abstract:INTRODUCTION:breast milk, besides being a source of feeding for children, it can be a vehicle for transmission of some infectious diseases. AIM:to revise the main viral agents which can be acquired for children through breast milk and its possible clinical implication. MATERIAL:literature search was made in different...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.3305/nh.2015.32.1.8794
更新日期:2015-07-01 00:00:00
abstract:Introduction:Aging is associated, per se, with the loss of functional reserve of different organs and systems, a greater risk of vulnerability and frailty, sarcopenia and malnutrition, a reality that is extended to cancer patients. There are several factors that are associated with malnutrition in the elderly individua...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.02986
更新日期:2020-07-01 00:00:00
abstract:AIMS:To assess, using a posterioritechniques, prevailing food consumption patterns of university students in Zamora and their association with food groups, in order to know how far can be away from a healthy diet, such as the Mediterranean diet. METHODS:Cross-sectional, descriptive and observational study of a represe...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1147
更新日期:2017-11-14 00:00:00
abstract:BACKGROUND:the prognostic value of maximal inspiratory and expiratory pressures on functional capacity and mortality of hospitalized patients are not well established. AIM:to evaluate the prognostic value of respiratory pressures in hospitalized patients. METHODS:patients admitted to a general hospital in Santiago-Ch...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1478
更新日期:2018-05-17 00:00:00
abstract::When a patient needs parenteral or enteral nutrition, be it in a transitory way or as a permanent form, and hospitalization is not strictly required, this treatment should take place in the home of the patient whenever possible. The support with artificial nutrition can be equally efficient, improving the life expecta...
journal_title:Nutricion hospitalaria
pub_type: 指南,杂志文章,实务指引
doi:
更新日期:1995-09-01 00:00:00
abstract::Resection of long segments of the small bowel may cause variable degrees of malabsorption. Therefore, the results of the resection will depend on the length and location of the resected segment, and on the age of the patient and the underlying disease that motivated the resection. The implementation of Nutritional Sup...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract:INTRODUCTION:The beneficial effects of the overall Mediterranean dietary pattern on cardiovascular risk factors and on carbohydrate metabolism are well known; however, it is unclear whether the consumption of olive oil in particular is able to reduce the incidence of type 2 diabetes. OBJECTIVE:To evaluate the specific...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::Over the last few years, obesity has been constantly increasing, thus turning it into a serious public health problem, with the subsequent impact on health-related expenditure, particularly in developed countries. The main peculiarity of obesity is its association with numerous pathologies (respiratory disease, cardio...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2004-01-01 00:00:00
abstract::An important area of the development of new functional foods is facussed on finding or applying food components which favour achieving a healthier lipid profile in the organism. The objective of this work was to carry out the characterisation of the lipid fraction of two oils, fish oil and algae oil, to evaluate their...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2006-05-01 00:00:00
abstract:INTRODUCTION:the apoB/apo A-I ratio has been reported as an important predictor of cardiovascular risk, being superior to lipids, lipoproteins and conventional lipid ratios. OBJECTIVE:to investigate the association between apolipoproteins A-I and B, and the apolipoprotein B/apolipoprotein A-I ratio and cardiometabolic...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.6.9779
更新日期:2015-12-01 00:00:00
abstract::We examined the possible changes undergone in the form of feeding post liver-transplant patients admitted to our Intensive Care Unit (ICU), comparing 1989 and 1992. As biological nutritional parameters, we reviewed blood lymphocyte values and albumin prior to the transplant, immediately after, seven days following and...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract:UNLABELLED:Weight loss and resolution of comorbidities is well established after modern bariatric procedures, however chronology of glyco-lipidic biochemical response is still debated. OBJECTIVE:Aiming to analyze this variable as well as its correlation with food amount and composition, a prospective study was designe...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Most of the initiation and maintenance pediatric formulas commercialized in Spain contain prebiotics and/or nucleotides aiming at achieving beneficial effects on prevention of different pathologies and immune protection, similar to human breast milk. However, according to the current legislation, its inclu...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.3305/nh.2012.27.4.5811
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Decrease in the capacity to deglutition solids and liquids is a problem in many people, this problem decreases quality of life. The objective of our study is to compare the acceptance of texture modifies courses against conventional courses. METHODS:A total of 70 patients were studied in our Hospital. First...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract:INTRODUCTION:The assessment of fetal development and birth weight is a priority in the field of nutritional epidemiology and public health. Nowadays, the World Health Organization (WHO) does not have specific birth weight curves for the distinct gestational weeks considering that socio-economic, ecological and ethnic c...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.2.7722
更新日期:2014-09-12 00:00:00
abstract:UNLABELLED:Morbid obesity is a risk factor for numerous diseases including liver disease with an incidence of hepatic steatosis from 70 to 80%. Although surgical treatment is effective in reducing weight, its effects on the liver have not been established convincingly. We report 2 cases of patients with bariatric surge...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.1.9174
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:to analyze the impact of front-of-pack warning labeling (FOP-L) on food purchase patterns in Chilean families with children under 14 years of age after the implementation of the law on nutritional labeling in Chile. METHODS:a cross-sectional study in 468 parents/tutors from 11 educational establishments in S...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03311
更新日期:2021-01-19 00:00:00
abstract::The liver is an important organ with specific functions that influence directly on the nutritional and physiological status of every person. At the presence of any illness or injury in this organ, liver cirrhosis is always its final phase. In this pathology, patients present carbohydrate utilization and storage dimini...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2014.29.2.7024
更新日期:2014-02-01 00:00:00
abstract:INTRODUCTION:weight and height measurements are important data for the nutritional assessment of elderly people and the implementation of the nutritional care process. Malnutrition is common in this population, who has high rates of disability that difficult to measurement this variables. OBJECTIVE:evaluate the validi...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.6.9760
更新日期:2015-12-01 00:00:00
abstract::Cereals are considered a basic food. Through the development of cooking, the human being has produced high- gluten-content food, so that it could make the most of its nutritional properties. Wheat is becoming one of the key elements of the Mediterranean diet. Amongst gluten- intake-related pathologies- gluten is prese...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2015.31.6.8984
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:The maintenance of healthy lifestyles is of great importance to prevent pregnancy-related diseases at early stages. For this reason, the knowledge of the overall wellbeing of women at childbearing-age is necessary to provide appropriate advice to maintain or improve the nutritional status. The aim of this re...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.29.2.7082
更新日期:2014-02-01 00:00:00
abstract::The term "conditionally essential" (or semi-essential), initially applied to amino acids, has been generalized to other nutrients. A conditionally essential nutrient is a compound usually produced in adequate amounts by endogenous synthesis but that is exogenously required under certain circumstances. Thus, arginine, ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2006-05-01 00:00:00
abstract:INTRODUCTION:The aim of the study was to estimate if B12 deficiency is associated with the use of metformin in the elderly diabetics. METHODS:Case-control study in diabetic OP. Cases (n = 137) were defined as elderly with B12 < 221 pmol/L and controls (n = 279) elderly with B12 > 221 pmol/L. Four categories of metform...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.29.6.7405
更新日期:2014-06-01 00:00:00
abstract:Introduction:Introduction: at present, it is precisely the Mediterranean countries whose characteristic lifestyle was recognized as a health paradigm and promoted to the rest of the world, those who are at mostly at risk, in which it becomes necessary the immediate development of strategies based on education that may ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.20960/nh.02685
更新日期:2019-07-02 00:00:00
abstract:OBJECTIVE:Recently, it has been reported that food choices of relatives of eating disorder (ED) patients are not adequate having in mind a healthy model of eating habits. The aim of this study was to analyse how work conditions relate to parents' food choice coping strategies in both families with a member suffering fr...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nutr hosp.v28in06.6840
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To check the correlation between gastric intolerance and hypertension intracranial pressure and their association with the clinical parameters and severity indexes in patients with severe head injury (HI); to evaluate the advantages of transpyloric feeding. DESIGN:Prospective and observational clinical study...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00