Abstract:
Introduction:Aging is associated, per se, with the loss of functional reserve of different organs and systems, a greater risk of vulnerability and frailty, sarcopenia and malnutrition, a reality that is extended to cancer patients. There are several factors that are associated with malnutrition in the elderly individual, such as the difficulty in regulating food intake, loss of appetite and anorexia associated with age, alteration of the senses of taste and smell, dysgeusia or economic problems. In the case of the cancer patient, other factors are added to these factors, such as: type of tumor; tumor stage; evolutionary moment of the disease; and baseline situation. Many therapeutic strategies used against the tumor, such as surgery, treatment with radiotherapy (concomitant or not with chemotherapy) and treatment with antitumor drugs influence also the risk of malnutrition. Thus, for example, concomitant chemo-radiation therapy in head and neck tumors, in lung cancer or in pelvic tumors represents a high nutritional risk antitumor therapy. Some of the repercussions of malnutrition in the oncological elderly are severe. Thus, for example, malnutrition in these individuals is associated with: worse survival; increased risk of early discontinuation of chemotherapy treatment; increased risk of chemotherapy toxicity; increased toxicity from other antitumor drugs; and increased risk of mortality during chemotherapy treatment. Taking this information into account, it is essential: to optimize the nutritional status in older patients with cancer prior to starting a systemic antitumor treatment; to carry out a nutritional follow-up throughout the treatment; and to offer early and intense management of malnutrition once it appears, with the purpose of minimizing the impact of antitumor drugs in older patients with cancer. Early management of malnutrition could improve drugs tolerance and increase the health-related quality of life in these patients. Introducción:El envejecimiento se asocia a la pérdida de reserva funcional de distintos órganos y sistemas, a un mayor riesgo de vulnerabilidad y de fragilidad, a la sarcopenia y a la malnutrición, realidad que se hace extensible a los pacientes oncológicos. Varios factores se asocian a la malnutrición en el individuo de edad avanzada: dificultad para regular la ingesta de alimentos, pérdida de apetito y anorexia asociadas a la edad, alteración de los sentidos del gusto y olfato, disgeusia o problemas económicos. En el caso del paciente oncológico, a estos factores se añaden otros como: tipo de tumor; estadio tumoral; momento evolutivo de la enfermedad; y situación basal. También las distintas estrategias terapéuticas utilizadas frente al tumor, como cirugía, tratamiento con radioterapia (concomitante o no a quimioterapia) y tratamiento con fármacos antitumorales influyen en el riesgo de malnutrición. Así, por ejemplo, la quimio-radioterapia concomitante en tumores de cabeza y cuello, en cáncer de pulmón o en tumores de localización pélvica, representa una terapia antitumoral de alto riesgo nutricional. Algunas de las repercusiones de la malnutrición en el anciano oncológico son severas. La malnutrición en estos individuos se asocia a: peor supervivencia; mayor riesgo de interrupción precoz del tratamiento con quimioterapia; aumento en el riesgo de toxicidad de la quimioterapia; mayor toxicidad por otros fármacos antitumorales; y riesgo incrementado de mortalidad durante el tratamiento con quimioterapia. Teniendo en cuenta esta información, resulta fundamental optimizar el estado nutricional en el anciano oncológico previo al inicio de un tratamiento antitumoral sistémico, hacer un seguimiento a lo largo del tratamiento y ofrecer un manejo precoz e intenso de la malnutrición una vez aparezca, con la finalidad de minimizar el impacto de los fármacos antitumorales en el anciano, de mejorar la tolerancia de tales fármacos y aumentar la calidad de vida relacionada con la salud en estos pacientes.
journal_name
Nutr Hospjournal_title
Nutricion hospitalariaauthors
Molina-Garrido MJdoi
10.20960/nh.02986subject
Has Abstractpub_date
2020-07-01 00:00:00pages
22-30issue
Spec No1eissn
0212-1611issn
1699-5198journal_volume
34pub_type
杂志文章abstract:INTRODUCTION:We may define Modular Parenteral Nutrition (MPN) as parenteral nutrition (PN) mixtures obtained from adding different macronutrients to standard formulations (SPN) both binary (amino acids and glucose) and ternary (amino acids, lipids, and glucose). OBJECTIVES:The aim of this study is to demonstrate that ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2007-07-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:Evaluate the safety and efficacy of a novel polyvitaminic (Aquadek's®) in patients with Cystic Fibrosis (CF). MATERIAL AND METHODS:Prospective, longitudinal and non-randomized study. CF patients with pancreatic insufficiency and clinically stable were given Aquadek's® (two chewable tablets) ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.4.8281
更新日期:2015-04-01 00:00:00
abstract::This computer program has been written in a BASIC language and designed to assess the nutritional status by means of anthropometrical, immunological and clinical data. Additionally, it is useful for the design and elaboration of personalized diets. The use of this program will allow to work with a great amount of nutr...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract:INTRODUCTION:Gestational diabetes has been associated with obesity later in life. However, reported results have not been consistent and the methods used have shown weakness. OBJECTIVE:To analize prospective and retrospective cohort studies that assess the gestational diabetes effects on adiposity indicators in the of...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.3305/nh.2014.29.2.7042
更新日期:2014-02-01 00:00:00
abstract::Nowadays, publications on probiotics have increased exponentially. However they usually are heterogeneous, use diverse strains and doses, and different outcomes, making it difficult to generalize their results. On the basis of the currently available literature, the use of probiotics is supported in the following dise...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2015.31.sup1.8703
更新日期:2015-02-07 00:00:00
abstract::Introducción: a escala mundial y nacional se reporta una alta prevalencia de sobrepeso y obesidad en menores de 5 años. La etiología es multifactorial, pero factores ambientales como sedentarismo y el progresivo deterioro de la alimentación promueven el exceso de peso y conllevan a mayor riesgo de enfermedades crónica...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.566
更新日期:2016-09-20 00:00:00
abstract:OBJECTIVE:To identify attitudinal determinants of fish consumption in Spain and Poland, and to discuss the potential impact of local healthy eating policies in the observed reported frequency of fish consumption. DESIGN:Repeated survey analysis , multivariate linear regression analysis. Data collected through a questi...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.1590/S0212-16112011000600031
更新日期:2011-11-01 00:00:00
abstract:INTRODUCTION:Food-Based Dietary Guidelines (FBDGs) are an initiative by the United Nations Food and Agriculture Organization (FAO) and the World Health Organization (WHO) designed to help countries establish their own nutrition education principles. Such principles should be expressed through clear and specific message...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2015.32.3.9362
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:To determine possible associations between the risk of breast cancer in Brazilian women and demographic, social and economical variables, and past dietary intake. METHODS:A case-control study was conducted in Joinville, Santa Catarina, Brazil, between june and november 2003 involving a group of 33 women rece...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,多中心研究
doi:
更新日期:2007-09-01 00:00:00
abstract:INTRODUCTION:Approximately two thirds of cancer patients at advanced stages of the disease suffer from anorexia. Defined as the loss of the desire to eat, anorexia lower the energy intake which further exacerbates a progressive deterioration of the patient nutritional status. Malnutrition has a large impact on morbidit...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.1590/S0212-16112011000400003
更新日期:2011-07-01 00:00:00
abstract::The relationship between adequate folate intake, adequate serum levels, and lowering the risk of suffering from cardiovascular diseases, neural tube defects, neural illness and some kind of cancers have been widely studied. Because of the expected health benefits, the consumption of foods with high folate content or e...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-01 00:00:00
abstract::Texture modified diet is a significant loss of the organoleptic qualities of the feed, so often associated with suboptimal intake and can increase the risk of malnutrition in people with chewing or swallowing difficulties. It is known that these diets based on traditional ground, have varying nutritional adequacy. The...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2014.29.4.7285
更新日期:2014-01-21 00:00:00
abstract:AIM:to evaluate the impact of a prenatal nutritional assistance proposal (PNA) for adult pregnant women. METHODS:a study of the impact of an applied nutritional intervention throughout the prenatal on perinatal outcomes - adequacy of total gestational weight gain, gestational anemia frequency and pregnancy complicatio...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.2.9045
更新日期:2015-08-01 00:00:00
abstract:INTRODUCTION:Body weight measurement is of critical importance when evaluating the nutritional status of patients entering a hospital. In some situations, such as the case of patients who are bedridden or in wheelchairs, these measurements cannot be obtained using standardized methods. We have designed and validated a ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2013.28.3.6455
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:The rapid increase on life-expectancy represents a major challenge and economic burden for modern societies. Several studies have focused on the effects of polyunsaturated fatty acids (PUFA) upon the immune system; however less attention has been paid to the effects of monounsaturated fatty acids (MUFA). I...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2013.28.2.6183
更新日期:2013-03-01 00:00:00
abstract:UNLABELLED:Nutritional management is essential in anorexia nervosa (AN), although nutrient replenishment must be done progressively to prevent the occurrence of re-alimentation syndrome. OBJECTIVE:to compare resting enengy expenditure (REE) by means of indirect calorimetry and by different equations in AN female patie...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract::Breast milk is regarded as an ideal source of nutrients for the growth and development of neonates, but it can also be a potential source of pollutants. Mothers can be exposed to different contaminants as a result of their lifestyle and environmental pollution. Mercury (Hg) and arsenic (As) could adversely affect the ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.30.2.7441
更新日期:2014-08-01 00:00:00
abstract:INTRODUCTION:Currently there is a growing trend in the prevalence of overweight and obesity. This increased prevalence trend leads to an increase in the costs of health care. OBJECTIVE:The aim of the present study was to analyze the effects on physical fitness and bone mineral density through an intervention program o...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.30.3.7365
更新日期:2014-09-01 00:00:00
abstract:INTRODUCTION:There is scarce and inconsistent information about gender-related differences in the hydration of sports persons, as well as about the effects of hydration on performance, especially during indoor sports. OBJECTIVE:To determine the physiological differences between genders during in indoor physical exerci...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,随机对照试验
doi:10.3305/nh.2014.29.3.7017
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:The nutritional care for HIV patients in Chile is a challenge for public health due to the absence of ministerial guidelines to ensure standardized and timely nutritional care that helps to enhance immunity and delay immunological failure from a preventive approach. OBJECTIVE:To design a proposal of protoco...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.2.7888
更新日期:2014-11-18 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine associations between abdominal obesity (AOb) and the other components of metabolic syndrome (MetS) in young Mexicans in a cross-sectional survey completed during a 4 year period. METHODS:This cross-sectional study reports on components and prevalence of MetS by us...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.171
更新日期:2017-03-30 00:00:00
abstract:OBJECTIVE:the aim was to establish reference standards for waist/hip ratio among Colombia children and adolescent aged 9 to 17.9 years who participated in "The FUPRECOL Study". METHODS:cross-sectional study. A sample of 3 005 children and 2 916 adolescents healthy Colombian youth (boys n = 2 542 and girls n = 3 384) p...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.5.9633
更新日期:2015-11-01 00:00:00
abstract::The present work aims to study the use of enteral nutrition (EN) products during the period between October 1996 and January 1997, in a general hospital with a nutrition unit. The EN expenditure ascended to 3,343,475 Pesetas, with the supplements representing the greatest cost percentage (39.1%). An indication-prescri...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::There are different parameters aimed at assessing nutritional status. These parameters may be of some help to assess nutritional status prior to patients' admission. However, their application in the critically ill patient is troublesome since results interpretation is interfered by changes originated by the acute dis...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract::The purpose of this retrospective study is to ascertain the physiopathological characteristics of patients on parenteral nutrition (PN), the types of diet used and duration of treatment. Presentation of epidemiological results and evolution of 637 adults receiving PN after a five-year period of nutritional follow-up, ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::The importance of the treatment of diabetes mellitus in the diet, is well known. Given that the glycemic response of the foods can not be predicted simply based on their chemical composition, prior to advising diabetics, one must have comparative data on the physiologic effects of the different foods. In this work we ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:physical fitness is a powerfull indicator of the health coindition in childhood, adolescence and adulthood. This research is performed in order to determine the age and gender stratified reference values for healthy physical fitness for Macodonian children and adolescents and to identify signicicant gender d...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1881
更新日期:2018-12-03 00:00:00
abstract:RATIONALE:The ELAN Ecuadorian Study of Hospital Malnutrition returned a malnutrition rate of 37.1% in public hospitals of Ecuador [Gallegos Espinosa S, Nicolalde Cifuentes M, Santana Porbén S; para el Grupo Ecuatoriano de Estudio de la Desnutrición Hospitalaria. State of malnutrition in hospitals of Ecuador. Nutr Hosp ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.1.8178
更新日期:2014-10-03 00:00:00
abstract::One of the generic indications of parenteral peripheral malnutrition is the immediate postoperative period following surgery of the digestive tract. In the series presented, fifty patients with digestive neoplasia of different locations were studied, with slight or moderate malnutrition upon admittance. After the oper...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract:Introduction:Aim: this study was performed to investigate the association between selenium concentrations, dietary intake, and the risk of hepatocellular carcinoma (HCC). Methods: we identified eligible studies in PubMed and EMBASE databases, in addition to the reference lists of original studies and review articles on...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析
doi:10.20960/nh.02776
更新日期:2019-12-26 00:00:00