Anti-ovalbumin antibody binds to 3T3 cells and induces DNA synthesis.

abstract：:Lyophilized bacterial lysates, which actively stimulate the immune response, are widely used as vaccines or 'biological response modifiers' in subjects with recurrent bacterial respiratory infections. Since vaccines are indicated in the absence or in the presence of a weak constitutive immune response activity, a bett...

journal_title：Immunology letters

authors： Rossi GA,Peri C,Raynal ME,Defilippi AC,Risso FM,Schenone G,Pallestrini E,Melioli G

更新日期：2003-03-03 00:00:00

abstract：:Normal and tumor-bearing host (TBH) peritoneal macrophage (M phi) responses to in vitro lipopolysaccharide (LPS) treatment were measured by assessing functional and phenotypic changes. Both normal and TBH untreated M phi suppressed mixed lymphocyte reaction (MLR) reactivity at all concentrations. Normal host M phi tre...

journal_title：Immunology letters

authors： Askew D,Yurochko AD,Burger CJ,Elgert KD

更新日期：1990-03-01 00:00:00

abstract：:Several studies have implicated a role for the cell surface glycoprotein CD44 in lymphocyte differentiation, adhesion to the matrix, homing, activation and apoptosis. However, the requirement of CD44 in B cell maturation remains elusive. To address this point, we analyzed the generation and activation of B lymphocytes...

journal_title：Immunology letters

authors： Bradl H,Schuh W,Jäck HM

更新日期：2004-08-15 00:00:00

abstract：:The cell-surface glycoproteins encoded by the major histocompatibility complex (MHC) bind to processed foreign antigens and present them to T lymphocytes. Two classes of MHC molecules and their corresponding gene sequences have been extensively studied in eutherian mammals and birds, but data on the marsupial MHC are ...

journal_title：Immunology letters

authors： Lam MK,Belov K,Harrison GA,Cooper DW

更新日期：2001-02-01 00:00:00

abstract：:Mouse trisomy 16 (Ts16), an animal model for human Down syndrome (trisomy 21), exhibits severe abnormalities in the development of lymphoid and myeloid cells. Whereas fetal liver cells from diploid mice can be easily immortalized by retroviral transformation with Ab1-MuLV or J2 virus, fetal livers from Ts16 mice conta...

journal_title：Immunology letters

authors： Berger CN,Epstein CJ

更新日期：1992-06-01 00:00:00

abstract：:Even though IgA is considered to play an important role in immunity, surprisingly little is known about the presence of IgA Fc receptor (Fc alpha R)-expressing effector cells in tissues. Difficulties in obtaining human tissue macrophages, led us to study peritoneal macrophages in a human Fc alpha RI transgenic (Tg) mo...

journal_title：Immunology letters

authors： van Egmond M,Hanneke van Vuuren AJ,van de Winkel JG

更新日期：1999-05-03 00:00:00

abstract：:It has been considered before that human naive and memory/effector CD4+ T-cells cannot be subdivided solely according to the differential expression of CD45 isoforms. By the lack of expression of CD31 we have identified a subset of CD4+ CD45RA+ CD31- cells which show distinct features of antigen-experienced Th1 cells....

journal_title：Immunology letters

authors： Thiel A,Schmitz J,Miltenyi S,Radbruch A

更新日期：1997-06-01 00:00:00

abstract：:It has been previously shown that normal human peripheral blood mononuclear cells produce a soluble factor(s) that causes selective inhibition of collagen production by cultured human diploid fibroblasts, and that stimulation of the mononuclear cells by appropriate mitogens greatly enhances its production. Because of ...

journal_title：Immunology letters

authors： Jimenez SA,Rosenbloom J

更新日期：1985-01-01 00:00:00

abstract：:Adult B-acute lymphoblastic leukemia (B-ALL) does not share the favorable prognosis seen in pediatric patients with the same disease. Less than 50% of patients experience long-term survival and for those adults over age 60, long-term survival is only 10%. At time of relapse, 5-year prognosis is a dismal 7%. Novel and ...

journal_title：Immunology letters

authors： Sikaria S,Aldoss I,Akhtari M

更新日期：2016-04-01 00:00:00

abstract：:This study aimed to investigate the influence of physical activity in innate immunity to conduce to an effective antitumoral immune response analyzing the phenotype and activation status of infiltrating cells. We analysed the intracellular cytokines and the transcription factors of tumor infiltrating lymphocytes (TILS...

journal_title：Immunology letters

authors： Bianco TM,Abdalla DR,Desidério CS,Thys S,Simoens C,Bogers JP,Murta EFC,Michelin MA

更新日期：2017-10-01 00:00:00

abstract：:We examined the alphabeta T cell receptor (TCR) repertoire of naturally occurring CD4+CD25+ regulatory T (Treg) cells isolated from healthy human blood. Three-color FACS analysis demonstrated that the usage of variable region segments of TCRbeta chains by CD4+CD25+ cells did not differ from those of CD4+CD25- cells. C...

journal_title：Immunology letters

authors： Fujishima M,Hirokawa M,Fujishima N,Sawada K

更新日期：2005-07-15 00:00:00

abstract：:Many alterations of innate and adaptive immunity are common in the aging population, which reflect a deterioration of the immune system, and have lead to the terms "immune aging" or "immunosenescence". Systems Biology aims to the comprehensive knowledge of the structure, dynamics, control and design that define a give...

journal_title：Immunology letters

authors： O'Connor JE,Herrera G,Martínez-Romero A,de Oyanguren FS,Díaz L,Gomes A,Balaguer S,Callaghan RC

更新日期：2014-11-01 00:00:00

abstract：:Despite the prominent progress in understanding cancer immunosurveillance mechanisms, there are some types of problems which have been identified to hinder effective and successful immunotherapy of cancers. Such problems have been ascribed to the tumor abilities in the creation of a tolerant milieu that can impair imm...

journal_title：Immunology letters

authors： Bahrambeigi S,Molaparast M,Sohrabi F,Seifi L,Faraji A,Fani S,Shafiei-Irannejad V

更新日期：2020-04-01 00:00:00

abstract：:The effects of interferon-alpha (IFN-alpha), INF-gamma, transforming growth factor beta (TGF-beta) and dexamethasone on low-affinity Fc receptors for IgE (Fc epsilon R2/CD23) expression on a human eosinophilic leukemia cell line, Eol-3, were examined. Fc epsilon R2/CD23 expression was enhanced by both IFN-alpha and IF...

journal_title：Immunology letters

authors： Watanabe H,Kawabe T,Yodoi J,Tanaka M,Kim KM,Nambu M,Tsuruta S,Morita M,Yorifuji T,Mayumi M

更新日期：1990-09-01 00:00:00

abstract：:The presence of dendritic cells (DCs) in mycobacterium-containing granulomas, as well as in other granuloma-inducing diseases, is beginning to be appreciated. This review will summarize what is known about DCs with regards to the granuloma and discuss the potential roles DCs may be playing during mycobacterial infecti...

journal_title：Immunology letters

authors： Schreiber HA,Sandor M

更新日期：2010-05-04 00:00:00

abstract：:In spite of impressive results in the treatment of acute lymphoblastic B cell leukemia (B-ALL) with chimeric antigen receptor (CAR) T cells, the clinical outcome of some hematological cancers like follicular lymphoma (FL) and chronic lymphocytic leukemia (CLL) has not been very promising likely due to immunosuppressiv...

journal_title：Immunology letters

authors： Fallah-Mehrjardi K,Mirzaei HR,Masoumi E,Jafarzadeh L,Rostamian H,Khakpoor-Koosheh M,Alishah K,Noorbakhsh F,Hadjati J

更新日期：2020-07-01 00:00:00

abstract：:The antibody response in humans naturally primed to a malaria vaccine candidate antigen (Pf155/RESA) is genetically regulated. Here, the impact of antigen presenting cells (APC) on the control of in vitro T-cell responses induced by Pf155/RESA or synthetic peptides corresponding to its major Pf155/RESA epitopes was st...

journal_title：Immunology letters

authors： Troye-Blomberg M,Lepers JP,Sjöberg K,Rahalimalala L,Larsson A,Olerup O,Perlmann P

更新日期：1994-12-01 00:00:00

abstract：:Work on mast cells and basophils began with their identification by Paul Ehrlich at the end of the 19th century. Mast cells and basophils were immediately perceived as closely linked cells and early nomenclature formulated by Ehrlich himself, i.e., tissue "Mastzellen" and blood "Mastzellen", reflected this unifying vi...

journal_title：Immunology letters

authors： Crivellato E,Nico B,Ribatti D

更新日期：2011-12-30 00:00:00

abstract：:A variety of cell types may be involved in the regulation of IgA secretion at the intestinal mucosa. Intestinal epithelial cells (IEC) are known to have the capacity to secrete several cytokines which may exert an important regulatory effect on local immunoglobulin secretion by mucosal B cells. In this study, we have ...

journal_title：Immunology letters

authors： Goodrich ME,McGee DW

更新日期：1999-03-15 00:00:00

abstract：:The effect of priming with various antigens on subsequent vaccination with the pneumococcal conjugate vaccine (CPV) was determined using BALB/c mice. Priming with pneumococcal polysaccharide or cross-reactive polysaccharide did not inhibit the IgG response to CPV immunization. Additionally, live intranasal colonizatio...

journal_title：Immunology letters

authors： Rabquer B,Smithson SL,Shriner A,Julie Westerink MA

更新日期：2006-08-15 00:00:00

abstract：:Previously we reported that a mega-dose of Vitamin C enhanced the initial stage of delayed-type hypersensitivity reaction in Balb/c mice. In this study its effects were further evaluated as follows. Mice were administered Vitamin C intraperitoneally at 0.625 mg/day or at 5mg/day for variable days before, during, or af...

journal_title：Immunology letters

authors： Noh K,Lim H,Moon SK,Kang JS,Lee WJ,Lee D,Hwang YI

更新日期：2005-04-15 00:00:00

abstract：:Maturation of dendritic cells is a key step during induction of adaptive immune responses. Multiple pathways and factors are involved in the regulation of dendritic cell maturation. Alternative splicing of pre-mRNA, which is regulated by splicing factors, plays an important role in many biological processes, including...

journal_title：Immunology letters

authors： Jia R,Li X,Yu C,Fan M,Guo J

更新日期：2013-06-01 00:00:00

abstract：:The anaerobic bacterium Campylobacter pylori (Cp) is thought to be associated with chronic gastritis. This paper presents clinical data underpinning this view. Five patients with histological chronic gastritis as determined by diagnostic endoscopy, which was associated with Cp as determined by positive biopsy cultures...

journal_title：Immunology letters

authors： van Bohemen CG,Langenberg ML,Rauws EA,Oudbier J,Weterings E,Zanen HC

更新日期：1989-01-15 00:00:00

abstract：:The present study was conducted to investigate the mode of cell death of bone marrow cells (BMC) treated in vivo or in vitro with gangliosides (DLG) derived from a T cell lymphoma, designated as Dalton's lymphoma (DL). BMC undergoing cell death showed morphological features characteristic to apoptosis such as cell shr...

journal_title：Immunology letters

authors： Bharti AC,Singh SM

更新日期：2000-04-03 00:00:00

abstract：:The production of interleukin 1 (IL-1) by lipopolysaccharide (LPS)-stimulated myelomonocytic cell lines ML-1, THP-1 and PL-21 was significantly enhanced by the addition of insulin, insulin-like growth factor (IGF)-I or IGF-II into the cell cultures. The IL-1 activity in the supernatants from cell cultures stimulated w...

journal_title：Immunology letters

authors： Holán V,Minowada J

更新日期：1992-12-01 00:00:00

abstract：:Neuraminidases act as a virulence factors for several pathogens that invade the human body through Peyer's patch M-cells. Because of the structural similarity of Aleuria aurantia lectin (AAL) to neuraminidases, we hypothesized that AAL might also target human M-cells. In an in vitro human M-cell co-culture model signi...

journal_title：Immunology letters

authors： Roth-Walter F,Bohle B,Schöll I,Untersmayr E,Scheiner O,Boltz-Nitulescu G,Gabor F,Brayden DJ,Jensen-Jarolim E

更新日期：2005-09-15 00:00:00

abstract：:SJL mice develop resistance against tolerance between the 9th and 25th wk of life. This resistance is linked with a loss of suppressor capacity in the thymus. We have shown here that contact photosensitivity (CPS) decreases as a function of age and that this is due to an age-dependent increase in suppressor capacity. ...

journal_title：Immunology letters

authors： Cinader B,Clandinin MT,Koh SW,Brown WR,Ramsay CA

更新日期：1986-03-01 00:00:00

abstract：:The purpose of this study is to show that anti-Leu M1 antibody (anti-CD15), which has different staining characteristics in lymphoid and non-lymphoid cells, reacted against the surface antigen of a defined monoclonal B cell line. This antibody recognizes the sugar moiety, lacto-N-fucopentaose (LNF-III), which is linke...

journal_title：Immunology letters

authors： Takei M,Kang H,Tomura K,Ikeda E,Karasaki M,Nakauchi H,Okumura K,Sawada S

更新日期：1989-11-01 00:00:00

abstract：:The immunosuppressant rapamycin is known to be a potent inhibitor of cytokine driven proliferation of T-lymphocytes and other cell types. Here we have examined the effect of rapamycin on the myeloblastic cell line M1 which responds to interleukin-6 (IL-6) with growth arrest and monocytoid differentiation. Single-agent...

journal_title：Immunology letters

authors： Kloke O,Kummer G,Seeber S

更新日期：1997-11-01 00:00:00

abstract：:Experiments with malaria in mice suggest that protective immunity depends not only on antibody but also on activation of macrophages. Activated macrophages may cause intra-erythrocytic death of parasites by releasing reactive oxygen intermediates and/or tumour necrosis factor. Macrophage activation for both types of p...

journal_title：Immunology letters

authors： Playfair JH,Dockrell H,Taverne J

更新日期：1985-01-01 00:00:00