Targeting antigens to murine and human M-cells with Aleuria aurantia lectin-functionalized microparticles.

abstract：:Among tumor necrosis factor (TNF) superfamily, TNF-related apoptosis inducing ligand (TRAIL) along with TNF-alpha and FasL is known as death ligand due to its selective cytotoxicity against transformed tumor cells. TRAIL can also induce alternative angiogenic and/or proinflammatory signals other than apoptosis, howeve...

journal_title：Immunology letters

authors： Choi K,Song S,Choi C

更新日期：2008-05-15 00:00:00

abstract：:The first step in the clearance of apoptotic cells is chemotactic migration of macrophages towards the apoptotic cells guided by find-me signals provided by the dying cells. Upon sensing the chemotactic signals, macrophages release ATP. ATP is then degraded to ADP, AMP and adenosine to trigger purinergic receptors con...

journal_title：Immunology letters

authors： Joós G,Jákim J,Kiss B,Szamosi R,Papp T,Felszeghy S,Sághy T,Nagy G,Szondy Z

更新日期：2017-03-01 00:00:00

abstract：:HLA-specific antibodies generated by allo-immunization are supposed to be involved in the control of HIV infections by both the neutralizing capacity of HLA-specific antibodies (Abs) and HLA-specific Ab-dependent complement-mediated lysis (CML). We further characterized CML of HIV primary isolates induced by HLA-speci...

journal_title：Immunology letters

authors： Hildgartner A,Wilflingseder D,Gassner C,Dierich MP,Stoiber H,Bánki Z

更新日期：2009-09-22 00:00:00

abstract：:In several diseases where the immune system plays an important role there has been a tremendous progress in treatment efficacy during the last decades. Based on necessary basic science these improvements are results of rapid, numerous and open-minded clinical trials where pieces of positive results step by step have b...

journal_title：Immunology letters

authors： Ludvigsson J

更新日期：2014-05-01 00:00:00

abstract：:Nervous and immune systems share specific recognition molecules for signals that originate in both systems. The information substances are polypeptides and their receptors. They comprise the multi-directional information exchange network whereby brain and nervous system function including mood and emotion can be integ...

journal_title：Immunology letters

authors： Wiedermann CJ

更新日期：1987-12-01 00:00:00

abstract：:The aim of the present work was to develop an in vitro model of eosinophil cytotoxicity which mimics numerous in vivo situations characterized by complement activation through the alternative pathway. Our results demonstrate that eosinophilic granulocytes from patients with parasitic diseases and blood eosinophilia we...

journal_title：Immunology letters

authors： De Simone C,Ferrari M,Pugnaloni L,Ferrarelli G,Rumi C,Sorice F

更新日期：1986-01-01 00:00:00

abstract：:Sequence-comparison indicates existing sequence-similarity between receptor-binding regions of human type 1 IFNs (IFN-alpha, -beta and -omega) and HIV-1 gp41. Previous findings had suggested that the increased levels of antibodies against human IFN-alpha and -beta in HIV-1-infected individuals are associated with a co...

journal_title：Immunology letters

authors： Chen YH,Wu W,Yang J,Sui SF,Sun J,Dierich MP

更新日期：1999-08-03 00:00:00

abstract：:While cases of silicosis are often complicated by various autoimmune disorders, patients with asbestosis develop malignant tumors such as lung cancer and malignant mesothelioma. These differences may derive from different biological effects, particularly on immunological cells, of silica and asbestos. To find differen...

journal_title：Immunology letters

authors： Wu P,Hyodoh F,Hatayama T,Sakaguchi H,Hatada S,Miura Y,Takata-Tomokuni A,Katsuyama H,Otsuki T

更新日期：2005-04-15 00:00:00

abstract：:The effects of recombinant human interleukin 4 (rIL-4) on proliferation and differentiation on human myeloid/monocytic leukemia cell lines were examined. At high concentrations, rIL-4 had a slight enhancing effect on [3H]thymidine incorporation by U937 cells. rIL-4 markedly induced expression of the Fc epsilon recepto...

journal_title：Immunology letters

authors： Noma T,Nakakubo H,Hama K,Honjo T

更新日期：1989-06-15 00:00:00

abstract：:Mice were exposed to restraint stress for 3h. During this period, low body temperature (hypothermia, 39 degrees C-->less than 37 degrees C) and high blood glucose levels (hyperglycemia, 150 mg/dl-->up to 220 mg/dl) were simultaneously induced. Reflecting a stress-induced phenomenon, blood levels of catecholamines incr...

journal_title：Immunology letters

authors： Watanabe M,Tomiyama-Miyaji C,Kainuma E,Inoue M,Kuwano Y,Ren H,Shen J,Abo T

更新日期：2008-01-15 00:00:00

abstract：:Phagocytosis of latex beads by peritoneal macrophages was examined by means of flow cytometry (FCM). This assay revealed that adrenocorticotropic hormone (ACTH) suppressed phagocytosis in a dose-dependent manner. ACTH (1-24) was more suppressive than ACTH (1-39). Control phagocytosis was partially suppressed in Ca(2+)...

journal_title：Immunology letters

authors： Ichinose M,Sawada M,Maeno T

更新日期：1994-10-01 00:00:00

abstract：:Multiple activation signals (including antigen, co-stimulation, and cytokines) during T-cell priming affect the subsequent generation of memory T cells, whose survival is maintained by IL-7 and IL-15. Since the IL-7 receptor is highly expressed not only on the surface of memory T cells but also on naïve T cells, we pr...

journal_title：Immunology letters

authors： Guo Z,Wang G,Miyahara Y,Khattar M,Linkes SP,Wang C,Xia J,Pan Y,Chen W,He X,Stepkowski SM

更新日期：2010-02-16 00:00:00

abstract：:B cell activating factor belonging to the TNF family (BAFF, also called BLyS, TALL-1, THANK, or zTNF4) is an important survival factor for B cells, and is able to regulate T cell activation. Recently, we have demonstrated that human soluble BAFF (hsBAFF) potently elevates NK cell activity of murine splenic cells in vi...

journal_title：Immunology letters

authors： Zhang W,Wen L,Huang X,Liang J,Gao W,Zhang S,Chen L

更新日期：2008-10-30 00:00:00

abstract：:Four murine monoclonal antibodies (mAbs) showing similar reactivity with a cell-wall extract and mannan preparation obtained from Candida albicans were examined for epitope specificity. An enzyme-linked immunosorbent assay (ELISA) was used to determine total mAb binding to extracted cell-wall antigen when each mAb was...

journal_title：Immunology letters

authors： Chaffin WL,Morrow KJ Jr

更新日期：1989-07-01 00:00:00

abstract：:Part of pathogen-associated molecular pattern (PAMP) and damage-associated molecular pattern (DAMP) activate antigen-presenting cells through Toll-like receptors (TLRs) to initiate immune responses. However, controversy remains if TLR4 mediates DAMP signaling due to the confounding effects of potential LPS contaminati...

journal_title：Immunology letters

authors： Lee KM,Seong SY

更新日期：2009-06-30 00:00:00

abstract：:This study aimed to investigate the influence of physical activity in innate immunity to conduce to an effective antitumoral immune response analyzing the phenotype and activation status of infiltrating cells. We analysed the intracellular cytokines and the transcription factors of tumor infiltrating lymphocytes (TILS...

journal_title：Immunology letters

authors： Bianco TM,Abdalla DR,Desidério CS,Thys S,Simoens C,Bogers JP,Murta EFC,Michelin MA

更新日期：2017-10-01 00:00:00

abstract：:Colonization with Streptococcus pneumoniae (S. pneumoniae) is associated with an increased risk for recurrent wheeze and asthma. Killed S. pneumoniae showed some potential as an effective immunomodulatory therapy in a murine model of asthma. Murine studies demonstrated protection against allergic asthma by symbiotic b...

journal_title：Immunology letters

authors： Hartmann C,Behrendt AK,Henken S,Wölbeling F,Maus UA,Hansen G

更新日期：2015-03-01 00:00:00

abstract：:Classical swine fever (CSF) and pseudorabies (PR) are both major infectious diseases of pigs, causing enormous economic losses to the swine industry in many countries. A marker vaccine that enables differentiation of infected from vaccinated animals (DIVA) is highly desirable for control and eradication of these two d...

journal_title：Immunology letters

authors： Lei JL,Xia SL,Wang Y,Du M,Xiang GT,Cong X,Luo Y,Li LF,Zhang L,Yu J,Hu Y,Qiu HJ,Sun Y

更新日期：2016-06-01 00:00:00

abstract：:Interleukin-35 (IL-35) is a novel anti-inflammatory cytokine and has been shown to play an important role in maintaining immune homeostasis. However, the effect of IL-35 on human asthma remains unclear. The present study is to investigate the expression and significance of IL-35 in childhood asthma. Forty-one asthmati...

journal_title：Immunology letters

authors： Ma Y,Liu X,Wei Z,Wang X,Xu D,Dai S,Li Y,Gao M,Ji C,Guo C,Zhang L,Wang X

更新日期：2014-11-01 00:00:00

abstract：:We have mapped a T cell epitope in the circumsporozoite (CS) protein of the murine malaria parasite, Plasmodium yoelii. A 21-mer synthetic peptide corresponding to the amino acid positions 59-79 (referred to as Py1), induced specific proliferation in BALB/c and C57BL/6 mice, and provided help for the production of ant...

journal_title：Immunology letters

authors： Del Giudice G,Grillot D,Rénia L,Müller I,Corradin G,Louis JA,Mazier D,Lambert PH

更新日期：1990-08-01 00:00:00

abstract：:Human natural killer (NK) cell activity was not significantly affected by leukotriene (LT) B4 over a wide concentration range (10(-6)-10(-14) M), whether added directly to the NK cell assay or after preincubation of effector cells for 2 h with the drug before addition of Cr labelled K562 target cells. In addition, LTB...

journal_title：Immunology letters

authors： Hall TJ,Brostoff J

更新日期：1985-01-01 00:00:00

abstract：:The influence of human recombinant granulocyte-macrophage colony-stimulating factor (rH GM-CSF) on respiratory burst response of isolated human neutrophils was examined. Preincubation of cells with rH GM-CSF significantly increased the respiratory burst in response to formyl-methionyl-leucyl-phenylalanine (FMLP), meas...

journal_title：Immunology letters

authors： Leino L,Nuutila J,Pelliniemi TT,Rajamäki A

更新日期：1993-09-01 00:00:00

abstract：:Previously we reported that a mega-dose of Vitamin C enhanced the initial stage of delayed-type hypersensitivity reaction in Balb/c mice. In this study its effects were further evaluated as follows. Mice were administered Vitamin C intraperitoneally at 0.625 mg/day or at 5mg/day for variable days before, during, or af...

journal_title：Immunology letters

authors： Noh K,Lim H,Moon SK,Kang JS,Lee WJ,Lee D,Hwang YI

更新日期：2005-04-15 00:00:00

abstract：:Cytokine induced killer (CIK) cells have a powerful tumor cells killing activity both in vitro and in vivo and transfusion of these cells have become an adjuvant treatment for tumors. CIK cells are induced and amplified from peripheral blood mononuclear cells (PBMCs) with multiple cytokines. As CD4+CD25bri regulatory ...

journal_title：Immunology letters

authors： Zhao P,Zhu D,Zhang Z,Han B,Gao D,Wei X,Xie X,Li C,Sun W,Wang Q,Guo Q

更新日期：2017-01-01 00:00:00

abstract：:This report describes an immunoradiometric assay for Plasmodium falciparum in infected blood, based on a cross-reacting monoclonal antibody (mAb) raised against P. berghei. In this assay, binding of the mAb to intact P. berghei parasites coated on microtiter plates is inhibited by solubilized P. falciparum infected re...

journal_title：Immunology letters

authors： Pass A,Avidor B,Golenser J,Laskov R,Sulitzeanu D

更新日期：1985-01-01 00:00:00

abstract：:This study tested the hypothesis that the Vδ3 subset of human γδ T cells, like their Vδ2 counterparts, can influence differentiation, antibody secretion and cytokine production by B cells. Vδ3 T cells constitute a minor subset of peripheral blood lymphocytes but are enriched in the liver and gut and are expanded in pa...

journal_title：Immunology letters

authors： Petrasca A,Melo AM,Breen EP,Doherty DG

更新日期：2018-04-01 00:00:00

abstract：:Two crucial mediators of monocyte activation by lipopolysaccharide (LPS) are the acute phase plasma factor, lipopolysaccharide binding protein (LBP) and cell-surface-expressed CD14. Whether macrophage (M phi) recognized and respond to LPS in a similar manner is unknown. Here we show that human monocyte-derived M phi r...

journal_title：Immunology letters

authors： Jungi TW,Brcic M,Eperon S

更新日期：1996-12-01 00:00:00

abstract：:Proliferation of mouse lymph node lymphocytes in response to concanavalin A in serum-free medium is normally dependent upon the presence of transferrin. In the absence of transferrin, little proliferation occurred, but the response was restored by addition of the iron complex of pyridoxal isonicotinoyl hydrazone (FePI...

journal_title：Immunology letters

authors： Brock JH,Stevenson J

更新日期：1987-05-01 00:00:00

abstract：:Although there is growing evidence that NKT cells play an important role in various immune responses through the invariant T cell receptor, other cell surface molecules responsible for their function are not fully understood. Here we study the role of ICOS, the third member of the CD28 family of costimulatory receptor...

journal_title：Immunology letters

authors： Watanabe S,Ohnuki K,Hara Y,Ishida Y,Ikarashi Y,Ogawa S,Kishimoto H,Tanabe K,Abe R

更新日期：2010-01-18 00:00:00

abstract：:Both, HIV envelope proteins gp120 and gp41 can directly activate complement system, even in the absence of HIV-specific antibodies. During the budding process HIV acquires host membrane-associated molecules among these complement regulatory proteins (CRPs). The presence of CRPs on the viral surface rescues HIV from co...

journal_title：Immunology letters

authors： Bánki Z,Stoiber H,Dierich MP

更新日期：2005-03-15 00:00:00