Ex vivo application of delta-aminolevulinic acid induces high and specific porphyrin levels in human skin tumors: possible basis for selective photodynamic therapy.

abstract：:The in vitro cell survival, localization and ultrastructural changes following irradiation were examined in 9L glioma cells sensitized with a new photosensitizer, lysyl chlorin p6 (LCP). In clonogenic assays, LCP was 10-100-fold more phototoxic than photofrin II on a microgram/mL basis. Lysyl chlorin p6 uptake was blo...

journal_title：Photochemistry and photobiology

authors： Leach MW,Higgins RJ,Autry SA,Boggan JE,Lee SJ,Smith KM

更新日期：1993-11-01 00:00:00

abstract：:In this manuscript, we demonstrate the control of film thickness and surface wettability in the photochemical immobilization of poly (vinyl alcohol) (PVA) to a self-assembled monolayer (SAM) containing a phthalimide chromophore. Surface attachment is characterized by ellipsometry and contact angle measurements. The we...

journal_title：Photochemistry and photobiology

authors： Carroll GT,Turro NJ,Mammana A,Koberstein JT

更新日期：2017-10-01 00:00:00

abstract：:Assignment of the fluorescence spectrum of firefly luciferin in aqueous solutions was achieved by utilizing not only emission energies but also theoretical absorption spectra and relative concentrations as estimated by pKa values. Calculated Gibbs free energies were utilized to estimate pKa values. These pKa values we...

journal_title：Photochemistry and photobiology

authors： Hiyama M,Akiyama H,Yamada K,Koga N

更新日期：2014-01-01 00:00:00

abstract：:Cyclooxygenase (COX)-2 inhibitors are known to be used as chemopreventative agents against certain malignancies. Thus far, there has been very limited information on whether COX-2 inhibitors protect against chronic narrow-band UVB (NB-UVB)-induced immunosuppression. The present study investigated the effect of nonsele...

journal_title：Photochemistry and photobiology

authors： Wu Y,Tai CL,Wei H,He F,Wang Y,Zhao Y,Chen HD

更新日期：2008-03-01 00:00:00

abstract：:This review focuses on damage photosensitized by the fluoroquinolone (FQ) antibacterial drugs. Different models are employed to study biosubstrate photodamage mediated by FQs (organisms, cells, isolated biomolecules and super molecules). Being that the effect of environment (polarity of the medium, ions, pH, binding w...

journal_title：Photochemistry and photobiology

authors： de Guidi G,Bracchitta G,Catalfo A

更新日期：2011-11-01 00:00:00

abstract：:This paper focuses on the estimation of the UV Index (UVI) for all sky conditions using a simple analytical parameterization involving three independent variables: the solar zenith angle, the total ozone column and the clearness index. Measurements of the UVI made at Badajoz and Cáceres (Southwestern Spain) from Janua...

journal_title：Photochemistry and photobiology

authors： Antón M,Serrano A,Cancillo ML,García JA,Madronich S

更新日期：2011-03-01 00:00:00

abstract：:Current conditions of 2-11 kJ m(-2) day(-1) of UV-B radiation and temperatures of >30 degrees C during flowering in cotton cultivated regions are projected to increase in the future. A controlled environment study was conducted in sunlit growth chambers to determine the effects of UV-B radiation and temperature on phy...

journal_title：Photochemistry and photobiology

authors： Reddy KR,Kakani VG,Zhao D,Koti S,Gao W

更新日期：2004-05-01 00:00:00

abstract：:In clinical 5-aminolevulinic acid (ALA)-based photodynamic therapy (PDT) of skin tumors it is desirable to develop vehicles that minimize the penetration of ALA through normal stratum corneum and maximize it through the compromised stratum corneum of the tumors to improve tumor selectivity. We have designed a bioadhes...

journal_title：Photochemistry and photobiology

authors： Donnelly RF,Ma LW,Juzenas P,Iani V,McCarron PA,Woolfson AD,Moan J

更新日期：2006-05-01 00:00:00

abstract：:Tetraarylporphyrins substituted with nitro groups at beta-pyrrolic positions are potential candidates for electron-accepting pigments in model systems for photosynthesis. The photophysics of 2-nitro-5,10,15,20-tetra-p-tolylporphyrin and its zinc analog have been studied in order to evaluate this potential. The ground ...

journal_title：Photochemistry and photobiology

authors： Gust D,Moore TA,Luttrull DK,Seely GR,Bittersmann E,Bensasson RV,Rougée M,Land EJ,De Schryver FC,Van der Auweraer M

更新日期：1990-04-01 00:00:00

abstract：:A spectral resolution procedure was used to resolve the absorption, excitation and emission spectra of the fluorescein monoanion in a number of solvent-water mixtures. This permitted an analysis of the effect of the solvent environment on the spectral properties of the monoanion and on the lactone/monoanion/dianion tr...

journal_title：Photochemistry and photobiology

authors： Klonis N,Sawyer WH

更新日期：2000-08-01 00:00:00

abstract：:Photodynamic therapy (PDT) is an established therapeutic modality that uses nonionizing near-infrared light to activate photocytotoxicity of endogenous or exogenous photosensitizers (PSs). An ongoing avenue of cancer research involves leveraging PDT to stimulate antitumor immune responses; however, these effects appea...

journal_title：Photochemistry and photobiology

authors： Kercher EM,Nath S,Rizvi I,Spring BQ

更新日期：2020-03-01 00:00:00

abstract：:The response of normal brain to photodynamic therapy (PDT) was investigated in 62 Fisher rats. The animals were injected i.p. with Photofrin II (12.5 mg/kg). Forty-eight hours following injection, an area of dura 5 mm in diameter over the frontal cortex was photoactivated with red light (632 +/- 2 nm) at 100 mW cm-2, ...

journal_title：Photochemistry and photobiology

authors： Dereski MO,Chopp M,Garcia JH,Hetzel FW

更新日期：1991-07-01 00:00:00

abstract：:Fibrous proteins discolor on exposure to the UV component of sunlight. This effect is exacerbated in the presence of fluorescent whitening agents (FWAs), which are often applied to textiles to improve product brightness. Tryptophan photoproducts have been identified as significant contributors to protein photoyellowin...

journal_title：Photochemistry and photobiology

authors： Dyer JM,Clerens S,Cornellison CD,Murphy CJ,Maurdev G,Millington KR

更新日期：2009-11-01 00:00:00

abstract：:We previously reported that Shewanella oneidensis MR-1 is extremely sensitive to natural solar radiation (NSR). Here we analyzed the global transcriptional profile of MR-1 during a 1-h recovering period after exposure to ambient solar light at a dose that yields about 20% survival rate on a Luria-Bertani (LB) plate. W...

journal_title：Photochemistry and photobiology

authors： Qiu X,Tiedje JM,Sundin GW

更新日期：2005-11-01 00:00:00

abstract：:To clarify the role of the Golgi apparatus in photodynamic therapy-induced apoptosis, its signaling pathway was studied after photodynamic treatment of human cervix carcinoma cell line HeLa, in which a photosensitizer, 2,4,5,7-tetrabromorhodamine 123 bromide (TBR), was incorporated into the Golgi apparatus. Laser scan...

journal_title：Photochemistry and photobiology

authors： Ogata M,Inanami O,Nakajima M,Nakajima T,Hiraoka W,Kuwabara M

更新日期：2003-09-01 00:00:00

abstract：:Ultraviolet-A irradiation of a suprofen (2-[4-2(2-thenoyl) phenyl]propionic acid) (SPF) buffered solution (pH 7.4) in the presence of supercoiled pBR322 DNA leads to single strand breaks with the formation of an open circular form and subsequent linearization of the plasmid. On the basis of agarose gel electrophoresis...

journal_title：Photochemistry and photobiology

authors： Condorelli G,Constanzo LL,De Guidi G,Giuffrida S,Sortino S

更新日期：1995-07-01 00:00:00

abstract：:Work in the past 8 years, particularly in the past 1-2 years, has greatly expanded our understanding of the mechanisms by which ultraviolet irradiation stimulates melanogenesis in the skin. A direct effect of UV photons on DNA results in up-regulation of the gene for tyrosinase, the rate-limiting enzyme in melanin syn...

journal_title：Photochemistry and photobiology

authors： Gilchrest BA,Park HY,Eller MS,Yaar M

更新日期：1996-01-01 00:00:00

abstract：:The photoprocesses of berberine, palmatine, coralyne, sanguinarine, flavopereirine and ellipticine were studied in several solvents. The quantum yields Φ(Δ) of singlet molecular oxygen formation of berberine, palmatine and sanguinarine are moderate in dichloromethane (0.2-0.6) and much smaller in acetonitrile or trifl...

journal_title：Photochemistry and photobiology

authors： Görner H,Miskolczy Z,Megyesi M,Biczók L

更新日期：2011-03-01 00:00:00

abstract：:We study the fluorescence lifetime of the well-known 1-pyrene butyric acid (PBA) to assess oxygen concentrations in living cells. The behavior of the probe is first studied in water, ethanol, protein solution and liposome suspension. The Stern-Volmer plot of these solutions is linear, and the bimolecular reaction rate...

journal_title：Photochemistry and photobiology

authors： Ribou AC,Vigo J,Salmon JM

更新日期：2004-09-01 00:00:00

abstract：:In this work, the changes in isoflavone levels and the expression of genes involved in their biosynthesis were studied in two Astragalus by UPLC-MS and real-time PCR after 10 days of UV-B treatment (λmax  = 313 nm, 804 J m-2 ). Isoflavones were significantly induced by UV-B irradiation. The influence might be activate...

journal_title：Photochemistry and photobiology

authors： Liu Y,Liu J,Wang Y,Abozeid A,Tian DM,Zhang XN,Tang ZH

更新日期：2018-01-01 00:00:00

abstract：:5-geranoxypsoralen (Bergamottin) does not photosensitize bacteria or a bacterial virus. It does, however, photosensitize mammalian cells in tissue culture. Irradiation with either black light (300-400 nm) or fluorescent ceiling lights produced at least four photobiologically active degradation products, the chemical n...

journal_title：Photochemistry and photobiology

authors： Ashwood-Smith MJ,Ceska O,Warrington PJ,Morris TF,Altamirano M

更新日期：1992-04-01 00:00:00

abstract：:Changes in the emission fluorescence intensity of pheophorbide-a (PHEO) in the presence of carboquone (CARBOQ) were used to obtain the association constant, the number of CARBOQ molecules interacting with PHEO, and the fluorescence quantum yield of the complex. Excitation spectra of mixtures of PHEO and CARBOQ in etha...

journal_title：Photochemistry and photobiology

authors： Díaz-Espinosa Y,Crespo-Hernández CE,Alegría AE,García C,Arce R

更新日期：2011-03-01 00:00:00

abstract：:We report the spectroscopic properties of fluorescein, x-rhodamine, tetramethyl-rhodamine, attached to single strand, duplex DNA, and to the digestion products by DNAse I. The properties reported include: molar absorptivity, quantum yield, absorbance and fluorescence spectra, fluorescence lifetime, intrinsic lifetime ...

journal_title：Photochemistry and photobiology

authors： Delgadillo RF,Parkhurst LJ

更新日期：2010-03-01 00:00:00

abstract：:Endogenous cellular chromophores absorb ultraviolet A radiation (UVA, 290-320 nm), the major UV component of terrestrial solar radiation, leading to the formation of reactive oxidizing species that initiate apoptosis, gene expression and mutagenesis. UVA-induced apoptosis of T helper cells is believed to underlie the ...

journal_title：Photochemistry and photobiology

authors： Zhuang S,Kochevar IE

更新日期：2003-07-01 00:00:00

abstract：:The assessment model for ultraviolet radiation and risk "AMOUR" is applied to output from two chemistry-climate models (CCMs). Results from the UK Chemistry and Aerosols CCM are used to quantify the worldwide skin cancer risk avoided by the Montreal Protocol and its amendments: by the year 2030, two million cases of s...

journal_title：Photochemistry and photobiology

authors： van Dijk A,Slaper H,den Outer PN,Morgenstern O,Braesicke P,Pyle JA,Garny H,Stenke A,Dameris M,Kazantzidis A,Tourpali K,Bais AF

更新日期：2013-01-01 00:00:00

abstract：:Photobiomodulation therapy (PBMT) has anti-inflammatory, analgesic and regenerative properties. This systematic review aimed to critically appraise the published data of in vivo human randomized clinical trials (RCTs), and present a comprehensive overview of the efficacy of PBMT, as an adjunct to the nonsurgical perio...

journal_title：Photochemistry and photobiology

authors： Dalvi S,Benedicenti S,Hanna R

更新日期：2020-10-24 00:00:00

abstract：:Proton magnetic resonance imaging (MRI) and histological methods were used to evaluate photodynamic therapy (PDT)-induced hemorrhagic necrosis in the murine M1 tumor within 72 h of treatment of male DBA/2 mice. The effects of three photosensitizing drugs were investigated: Photofrin (n = 4), Zn (II) phthalocyanine (n ...

journal_title：Photochemistry and photobiology

authors： Winsborrow BG,Grondey H,Savoie H,Fyfe CA,Dolphin D

更新日期：1997-12-01 00:00:00

abstract：:The aim of this investigation is the evaluation of DNA interaction of with tetraruthenated porphyrin (TRP) and of DNA damage in the presence of light. Direct-fluorescence and electronic absorption measurements after incubation of DNA with TRP indicate strong binding between pBR322 DNA or calf thymus DNA with the modif...

journal_title：Photochemistry and photobiology

authors： Onuki J,Ribas AV,Medeiros MH,Araki K,Toma HE,Catalani LH,Di Mascio P

更新日期：1996-03-01 00:00:00

abstract：:A new type of photochromic molecule that can be used for diffusion coefficient (D) measurements of various proteins in solution is described. The absorption spectrum of this molecule is changed upon photoexcitation by the trans-cis isomerization reaction. Target proteins were labeled by this photochromic molecule in t...

journal_title：Photochemistry and photobiology

authors： Eitoku T,Terazima M

更新日期：2008-07-01 00:00:00

abstract：:Strawberry (Fragaria ananassa) fruit size and flavor are important to both growers and consumers. Plastic mulches are frequently used in raised-bed culture to conserve water, control weeds with less herbicides, keep fruit clean and produce ripe berries earlier in the season. The most commonly used plastic mulch color ...

journal_title：Photochemistry and photobiology

authors： Kasperbauer MJ,Loughrin JH,Wang SY

更新日期：2001-07-01 00:00:00