The photobiological activity of 5-geranoxypsoralen and its photoproducts.

abstract：:Copper(II), in the presence of UV-B radiation (280-315 nm), can generate single-strand breaks in the sugar-phosphate backbone of pBR322 plasmid DNA. A low level of single-strand backbone breaks occurs in the presence of Cu(II) alone, but UV-B irradiation increases the rate by the more than 100-fold. Concomitant with t...

journal_title：Photochemistry and photobiology

authors： Lloyd RE,Larson RA,Adair TL,Tuveson RW

更新日期：1993-06-01 00:00:00

abstract：:Chlorprothixene (CPTX, Taractan) is a low potency antipsychotic mainly used for the treatment of psychotic disorders (e.g. schizophrenia) and acute mania occurring as part of bipolar disorders. As in the case of other numerous drugs used in the treatment of psychiatric disorders, CPTX presents geometric isomerism. The...

journal_title：Photochemistry and photobiology

authors： Piñero LE,García C,Lhiaubet-Vallet V,Oyola R,Miranda MA

更新日期：2009-07-01 00:00:00

abstract：:Raman spectroscopy (RS) has potential for disease classification within the gastrointestinal tract (GI). A near-infrared (NIR) fiber-optic RS system has been developed previously. This study reports the first in vivo Raman spectra of human gastrointestinal tissues measured during routine clinical endoscopy. This was a...

journal_title：Photochemistry and photobiology

authors： Shim MG,Song LM,Marcon NE,Wilson BC

更新日期：2000-07-01 00:00:00

abstract：:Persister bacteria tolerate bactericidal antibiotics due to transient and reversible phenotypic changes. As these bacteria can limit the effectiveness of antibiotics to eradicate certain infections, their elimination is a relevant issue. Photodynamic therapy seems suitable for this purpose, but phenotypic tolerance to...

journal_title：Photochemistry and photobiology

authors： Oppezzo OJ,Forte Giacobone AF

更新日期：2018-01-01 00:00:00

abstract：:Catalases are oxidized by singlet oxygen giving rise to more acidic conformers detected in zymograms after electrophoresis in polyacrylamide gels. This shift in catalase mobility can be indicative of singlet oxygen production in vivo. Catalase from human cells, as from many organisms, is susceptible to in vitro modifi...

journal_title：Photochemistry and photobiology

authors： Lledías F,Hansberg W

更新日期：1999-12-01 00:00:00

abstract：:The role of water molecules in spectral tuning of proteins has been left largely unexplored. This topic is important because changing hydrogen bond patterns during the activation process may lead to spectral shifts which can be of diagnostic value for the underlying structures. Arguments put forward in this article ar...

journal_title：Photochemistry and photobiology

authors： Sekharan S

更新日期：2009-03-01 00:00:00

abstract：:A targeting strategy based on the selective enzyme-mediated activation of polymeric photosensitizer prodrugs (PPP) within pathological tissue has led to the development of agents with the dual ability to detect and treat cancer. Herein, a detailed study of a simple model system for these prodrugs is described. We prep...

journal_title：Photochemistry and photobiology

authors： Campo MA,Gabriel D,Kucera P,Gurny R,Lange N

更新日期：2007-07-01 00:00:00

abstract：:The quantum yield, phi ZE, for configurational photoisomerization (4Z,15Z----4Z,15E) of bilirubin bound non-covalently to human serum albumin was determined (at 23 +/- 2 degrees C) by laser excitation and chromatographic analysis of products. Values obtained for photoexcitation at 465 nm were about one-half those prev...

journal_title：Photochemistry and photobiology

authors： Agati G,Fusi F,Pratesi R,McDonagh AF

更新日期：1992-02-01 00:00:00

abstract：:New thio- and seleno-analogs of psoralen were synthesized and analyzed for their photoreactivity toward DNA. Using oligonucleotides of defined sequence, we first showed that these derivatives predominantly generated interstrand crosslinks at 5'-TpA sites. We also observed a surprisingly high reactivity of 7H-thiopyran...

journal_title：Photochemistry and photobiology

authors： Collet M,Sage E,Piette J

更新日期：1997-08-01 00:00:00

abstract：:The individual tryptophanyl contributions to the near-ultraviolet dichroic activity of apomyoglobin in its native conformation have been resolved. This was accomplished by comparing the spectra of two classes of apomyoglobin with different aromatic residue contents and observing the effect of a specific modification o...

journal_title：Photochemistry and photobiology

authors： Sirangelo I,Irace G,Bismuto E

更新日期：1994-06-01 00:00:00

abstract：:The photophysical properties of Piroxicam, a nonsteroidal anti-inflammatory drug (NSAID), were investigated at different pHext values in reversed micelles of Aerosol-OT (AOT) in iso-octane, using both steady-state and picosecond time-resolved fluorescence spectroscopy. In contrast with the very complex data obtained i...

journal_title：Photochemistry and photobiology

authors： Andrade SM,Costa SM,Pansu R

更新日期：2000-04-01 00:00:00

abstract：:The retina and retinal pigment epithelium contain a number of retinoids in a metabolic pathway that eventually forms the visual pigments. This study investigates the photochemistry of those retinoids that may contribute to light-induced damage to the retina. These include retinal (RAL), retinol (ROL), retinylpalmitate...

journal_title：Photochemistry and photobiology

authors： Dillon J,Gaillard ER,Bilski P,Chignell CF,Reszka KJ

更新日期：1996-05-01 00:00:00

abstract：:The dependence of autofluorescence properties on the metabolic and functional engagement and on the transformation condition was studied on single cells. Normal Galliera rat fibroblasts at low subculture passage (cell strain), at high subculture passage (stabilized cell line), and transformed cell line derived from a ...

journal_title：Photochemistry and photobiology

authors： Croce AC,Spano A,Locatelli D,Barni S,Sciola L,Bottiroli G

更新日期：1999-03-01 00:00:00

abstract：:Nowadays, introducing self-cleaning properties on various fabrics under daylight irradiation for automotive and upholstery application is in a central point of research. This can be achieved by application of metal-doped TiO2 nano particles on the textile fabrics. Here, alkali hydrolysis of polyester fabric has been c...

journal_title：Photochemistry and photobiology

authors： Gaminian H,Montazer M

更新日期：2015-09-01 00:00:00

abstract：:The cellular uptake, localization and efflux of meso-tetra-(4-hydroxyphenyl)porphyrin (p-THPP)-loaded nanoparticles have been studied in EMT-6 tumor cells. The effect of blood serum on photocytotoxicity has also been evaluated. Sub-130 nm nanoparticles based on poly(D,L-lactide-co-glycolide) (PLGA) (50:50 PLGA and 75:...

journal_title：Photochemistry and photobiology

authors： Konan YN,Chevallier J,Gurny R,Allémann E

更新日期：2003-06-01 00:00:00

abstract：:A careful study of the linoleic acid hydroperoxide (LOOH) profile obtained upon peroxidation of linoleic acid (LA) photosensitized by tiaprofenic acid (TPA) and analogous ketones has been undertaken to distinguish between type-I and type-II photoperoxidation mechanisms. 1,4-Cyclohexadiene and 1,2-dimethylcyclohexa-2,5...

journal_title：Photochemistry and photobiology

authors： Samadi A,Martínez LA,Miranda MA,Morera IM

更新日期：2001-04-01 00:00:00

abstract：:Efficient phagocytosis of photoreceptor outer segments (POS) membranes by retinal pigment epithelium (RPE) plays a key role in biological renewal of these highly peroxidizable structures. Here, we tested whether photodynamic treatment, mediated by merocyanine 540 (MC 540), rose Bengal or a zinc-substituted chlorophyll...

journal_title：Photochemistry and photobiology

authors： Olchawa M,Szewczyk G,Zareba M,Piłat A,Bzowska M,Mikołajczyk T,Sarna T

更新日期：2010-07-01 00:00:00

abstract：:Use of near infrared instead of visible light would markedly improve tissue penetration, making larger tumors candidates for photochemotherapy. Because common photesensitizers exhibit virtually no absorption in this wavelength region, conditions are required where the simultaneous action of two photons is possible. He...

journal_title：Photochemistry and photobiology

authors： Lenz P

更新日期：1995-08-01 00:00:00

abstract：:The multifunctional polypeptide cyclosporin synthetase (CySyn) remains one of the most complex nonribosomal peptide synthetase described. In this study we used a highly specific photoaffinity labeling procedure with the natural cofactor S-adenosyl-L-methionine (AdoMet), 14C-isotopically labeled at the Sdelta methyl gr...

journal_title：Photochemistry and photobiology

authors： Velkov T,Lawen A

更新日期：2003-02-01 00:00:00

abstract：:An ongoing study in our laboratories is to examine the relationship of DNA repair defects to human cancer. Our underlying hypothesis has been that human tumors may arise that lack interesting DNA repair pathways if these pathways are important in preventing cancer. In this study, we found that the UV-irradiated adenov...

journal_title：Photochemistry and photobiology

authors： Day RS 3rd,Rasouli-Nia A,Meservy J,Lari SU,Dobler K,Tsunoda S,Miyakoshi J,Takebe H,Murray D

更新日期：1999-08-01 00:00:00

abstract：:Photoautotrophic growth of Chlamydomonas reinhardtii was shown to be independent of the presence of atmospheric oxygen. Under constant light and photoautotrophic conditions, C. reinhardtii grew equally well in either air or 367 PPM CO2-in-He. During 12-h light-dark cycles, the cells in air grew substantially faster th...

journal_title：Photochemistry and photobiology

authors： Graves DA,Spradlin GM,Greenbaum E

更新日期：1990-09-01 00:00:00

abstract：:We examined the influence of solar ultraviolet-B radiation (UV-B; 280-320 nm) on the growth, biomass production and phenylpropanoid concentrations of Deschampsia antarctica during the springtime ozone depletion season at Palmer Station, along the Antarctic Peninsula. Treatments involved placing filters on frames over ...

journal_title：Photochemistry and photobiology

authors： Ruhland CT,Xiong FS,Clark WD,Day TA

更新日期：2005-09-01 00:00:00

abstract：:Channel and pump rhodopsins use energy from light absorbed by a covalently bound retinal chromophore to transport ions across membranes of microbial cells. Ion transfer steps, including proton transfer, can couple to changes in protein conformational dynamics and water positions. Although general principles of how mic...

journal_title：Photochemistry and photobiology

authors： Bondar AN,Smith JC

更新日期：2017-11-01 00:00:00

abstract：:We have compared the cytotoxicity of daunomycin in vitro to highly differentiated normal epithelial cells (Fisher rat thyroid cells, FRTL-5) and to two neoplastic cell lines, a thyroid carcinoma (TK-6) and its lung metastasis (MPTK-6). Whereas the cell lines are equally sensitive to the drug in the dark, if irradiated...

journal_title：Photochemistry and photobiology

authors： Andreoni A,Colasanti A,Kisslinger A,Mastrocinque M,Portella G,Riccio P,Roberti G

更新日期：1993-05-01 00:00:00

abstract：:The design, synthesis and application of a new fluorescent-labeling reagent for collagen has been developed as a prerequisite for the design of a photoactivated collagen-crosslinking compound for surgical wound closure. The amine groups in collagen are the targets of a rational design for a new fluorophore because nat...

journal_title：Photochemistry and photobiology

authors： Timberlake GT,Reddy GK,Stehno-Bittel L,Weber JF,Amslinger S,Givens RS

更新日期：2002-11-01 00:00:00

abstract：:All-trans retinoic acid (ATRA) plays essential roles in the normal biological processes and the treatment of cancer and skin diseases. Considering its photosensitive property, many studies have been focused on the photochemistry of ATRA. In this study, we investigated the transient phenomena in the laser flash photoly...

journal_title：Photochemistry and photobiology

authors： Li K,Wang M,Wang T,Sun D,Zhu R,Sun X,Wu X,Wang SL

更新日期：2013-09-01 00:00:00

abstract：:Antisense oligodeoxynucleotides directed against a 24-mer RNA derived from the long terminal repeat (LTR) region of HIV were linked to proto- and methylpyrroporphyrin and their zinc derivatives. The oligonucleotide-porphyrin conjugates were tested for their ability to induce photodamage on the target RNA. Upon hybridi...

journal_title：Photochemistry and photobiology

authors： Mastruzzo L,Woisard A,Ma DD,Rizzarelli E,Favre A,Le Doan T

更新日期：1994-10-01 00:00:00

abstract：:By a technique which combines rapid mixing of cells and hematoporphyrin (HP) with a short duration of illumination, the photodynamic inactivation of yeast cells was investigated, particularly, in seeking for the information of the location of HP at the time of action. The fluence-survival curves obtained under the con...

journal_title：Photochemistry and photobiology

authors： Ito T

更新日期：1981-10-01 00:00:00

abstract：:The incidence and prevalence of inflammatory bowel disease (IBD) are increasing worldwide. Some ecological studies show increasing incidence with increasing latitude. Ambient ultraviolet radiation varies inversely with latitude, and sun exposure of the skin is a major source of vitamin D. Vitamin D deficiency is commo...

journal_title：Photochemistry and photobiology

authors： Holmes EA,Rodney Harris RM,Lucas RM

更新日期：2019-01-01 00:00:00

abstract：:Stratospheric ozone depletion has caused an increase in the amount of ultraviolet-B (UV-B) radiation reaching the earth's surface. Numerous investigations have demonstrated that the effect of UV-B enhancements on plants includes reduction in grain yield, alteration in species competition, susceptibility to disease and...

journal_title：Photochemistry and photobiology

authors： Gao W,Zheng Y,Slusser JR,Heisler GM,Grant RH,Xu J,He D

更新日期：2004-07-01 00:00:00