Targeted photochemical modification of HIV-derived oligoribonucleotides by antisense oligodeoxynucleotides linked to porphyrins.

abstract：:The infrared spectrum of monomeric unsubstituted coumarin (C9H6O2; 2H-1-benzopyran-2-one), isolated in solid argon at 10 K is presented and assigned. The UV-induced (lambda>200 nm) unimolecular photochemistry of the matrix-isolated compound was studied experimentally. Three main photoreactions were observed: (a) decar...

journal_title：Photochemistry and photobiology

authors： Kuş N,Breda S,Reva I,Tasal E,Ogretir C,Fausto R

更新日期：2007-09-01 00:00:00

abstract：:Although the first reactive oxygen species (ROS) formed during irradiation of photosensitized cells is almost invariably singlet molecular oxygen (1O2), other ROS have been implicated in the phototoxic effects of photodynamic therapy (PDT). Among these are superoxide anion radical (*O2(-)), hydrogen peroxide (H2O2) an...

journal_title：Photochemistry and photobiology

authors： Price M,Terlecky SR,Kessel D

更新日期：2009-11-01 00:00:00

abstract：:Generating accurate population-specific public health messages regarding sun protection requires knowledge about seasonal variation in sun exposure in different environments. To address this issue for a subtropical area of Australia, we used polysulphone badges to measure UVR for the township of Nambour (26 degrees la...

journal_title：Photochemistry and photobiology

authors： Neale RE,Hamilton AR,Janda M,Gies P,Green AC

更新日期：2010-03-01 00:00:00

abstract：:Photodynamic therapy (PDT) oxygen consumption, clonogenic cell survival, fluorescence photobleaching and photoproduct formation were investigated during benzoporphyrin derivative monoacid (BPD-MA)-PDT of MAT-LyLu cells in vitro. Cells were incubated with BPD-MA concentrations of 0.1, 0.5 or 2.5 μg mL(-1) for 2 h and t...

journal_title：Photochemistry and photobiology

authors： Weston MA,Patterson MS

更新日期：2011-09-01 00:00:00

abstract：:We report the spectroscopic properties of fluorescein, x-rhodamine, tetramethyl-rhodamine, attached to single strand, duplex DNA, and to the digestion products by DNAse I. The properties reported include: molar absorptivity, quantum yield, absorbance and fluorescence spectra, fluorescence lifetime, intrinsic lifetime ...

journal_title：Photochemistry and photobiology

authors： Delgadillo RF,Parkhurst LJ

更新日期：2010-03-01 00:00:00

abstract：:Pyocyanin (PyO-) (1-hydroxy-5-methylphenazine) is a cytotoxic compound secreted by Pseudomonas aeruginosa, an omnipresent bacterium and a human pathogen. We report that visible light illumination in the presence of rose bengal, or riboflavin, in aerated solutions (pH 7.0-7.2) induces irreversible loss of the pigment's...

journal_title：Photochemistry and photobiology

authors： Reszka KJ,Denning GM,Britigan BE

更新日期：2006-03-01 00:00:00

abstract：:Color variants of Ca2+ -regulated photoprotein obelin were shown to be an important tool for dual-analyte binding assay. To provide site-directed conjugation with biospecific molecules, several obelin color mutants carrying unique cysteine residues were obtained and characterized for their novel properties. A pair of ...

journal_title：Photochemistry and photobiology

authors： Krasitskaya VV,Burakova LP,Komarova AA,Bashmakova EE,Frank LA

更新日期：2017-03-01 00:00:00

abstract：:Fibrous proteins discolor on exposure to the UV component of sunlight. This effect is exacerbated in the presence of fluorescent whitening agents (FWAs), which are often applied to textiles to improve product brightness. Tryptophan photoproducts have been identified as significant contributors to protein photoyellowin...

journal_title：Photochemistry and photobiology

authors： Dyer JM,Clerens S,Cornellison CD,Murphy CJ,Maurdev G,Millington KR

更新日期：2009-11-01 00:00:00

abstract：:UVB radiation contributes to both direct and indirect damage to the skin including the generation of free radicals and reactive oxygen species (ROS), inflammatory responses, immunosuppression and gene mutations, which can ultimately lead to photocarcinogenesis. A plant-derived flavonoid, baicalin, has been shown to ha...

journal_title：Photochemistry and photobiology

authors： Min W,Ahmad I,Chang ME,Burns EM,Qian Q,Yusuf N

更新日期：2015-11-01 00:00:00

abstract：:To determine the impact of delivery vehicles in photosensitizing efficacy of HPPH, a hydrophobic photosensitizer was dissolved in various formulations: 1% Tween 80/5% dextrose, Pluronic P-123 and Pluronic F-127 in 0.5%, 1% and 2% phosphate buffer solutions (PBS). HPPH was also conjugated to Pluronic F-127, and the res...

journal_title：Photochemistry and photobiology

authors： Cacaccio J,Durrani F,Cheruku RR,Borah B,Ethirajan M,Tabaczynski W,Pera P,Missert JR,Pandey RK

更新日期：2020-05-01 00:00:00

abstract：:Although strong fluorescence makes the R-phycoerythrin (R-PE) proteins increasingly useful in biological and clinical assays, they are subject to nonlinear effects including transitions to collective dark states and photodegradation, which complicate quantitative applications. We report measurements of R-PE fluorescen...

journal_title：Photochemistry and photobiology

authors： Gaigalas A,Gallagher T,Cole KD,Singh T,Wang L,Zhang YZ

更新日期：2006-05-01 00:00:00

abstract：:The kinetics of transients formed under photoexcitation of benzophenone (B) dissolved in three different polymers was studied by ns laser flash photolysis. These polymers were the soft rubbers poly (ethylene-co-butylene) (EB), polystyrene block-poly(ethylene-ran-butylene)-block-polystyrene (SEBS) and hard polystyrene ...

journal_title：Photochemistry and photobiology

authors： Levin PP,Efremkin AF,Sultimova NB,Kasparov VV,Khudyakov IV

更新日期：2014-03-01 00:00:00

abstract：:Skin cancer is the most prevalent cancer, and its assessment remains a challenge for physicians. This study reports the application of an optical sensing method, elastic scattering spectroscopy (ESS), coupled with a classifier that was developed with machine learning, to assist in the discrimination of skin lesions th...

journal_title：Photochemistry and photobiology

authors： Rodriguez-Diaz E,Manolakos D,Christman H,Bonning MA,Geisse JK,A'Amar OM,Leffell DJ,Bigio IJ

更新日期：2019-11-01 00:00:00

abstract：:Detergent solubilized bacteriorhodopsin (BR) proteins which contain alterations made by site-directed mutagenesis (Asp-96----Asn, D96N; Asp-85----Asn, D85N; and Arg-82----Gln, R82Q) have been studied with resonance Raman spectroscopy. Raman spectra of the light-adapted (BRLA) and M species in D96N are identical to tho...

journal_title：Photochemistry and photobiology

authors： Lin SW,Fodor SP,Miercke LJ,Shand RF,Betlach MC,Stroud RM,Mathies RA

更新日期：1991-03-01 00:00:00

abstract：:A targeting strategy based on the selective enzyme-mediated activation of polymeric photosensitizer prodrugs (PPP) within pathological tissue has led to the development of agents with the dual ability to detect and treat cancer. Herein, a detailed study of a simple model system for these prodrugs is described. We prep...

journal_title：Photochemistry and photobiology

authors： Campo MA,Gabriel D,Kucera P,Gurny R,Lange N

更新日期：2007-07-01 00:00:00

abstract：:We study the fluorescence lifetime of the well-known 1-pyrene butyric acid (PBA) to assess oxygen concentrations in living cells. The behavior of the probe is first studied in water, ethanol, protein solution and liposome suspension. The Stern-Volmer plot of these solutions is linear, and the bimolecular reaction rate...

journal_title：Photochemistry and photobiology

authors： Ribou AC,Vigo J,Salmon JM

更新日期：2004-09-01 00:00:00

abstract：:The chloride effect on the photobleaching process of iodopsin, a chicken red-sensitive cone visual pigment, was studied in detail by time-resolved low-temperature spectroscopy at -40 degrees C to -10 degrees C. Decay-associated difference spectra obtained by kinetic analysis using the singular value decomposition meth...

journal_title：Photochemistry and photobiology

authors： Imamoto Y,Shichida Y

更新日期：2008-07-01 00:00:00

abstract：:Antibodies and antigen binding fragments thereof were photochemically immobilized on surface-modified silicon chips of 5 x 5 mm size. Silicon surface-grafted diazirines and benzophenones formed covalent bonds with the immunoreagents on light activation. Photolithographic immobilization of monoclonal antibodies in aque...

journal_title：Photochemistry and photobiology

authors： Sundarababu G,Gao H,Sigrist H

更新日期：1995-06-01 00:00:00

abstract：:Aqueous solutions of KI were examined for use as chemical actinometers to measure 254 nm (germicidal) radiation. Irradiation results in electron ejection from iodide such that aqueous electrons and iodine atoms are formed. In the presence of N2O, an electron scavenger, recombination of these two reactive species is el...

journal_title：Photochemistry and photobiology

authors： Rahn RO

更新日期：1993-12-01 00:00:00

abstract：:In horticultural crops, the use of screens to protect plants is the usual strategy in the Mediterranean area. Screen manufacturers offer a range of netting that vary in their UV-absorbing properties. We compared the photoeffects of seven different screens. Sweet pepper trials were conducted at the Gilat Research Cente...

journal_title：Photochemistry and photobiology

authors： Legarrea S,Karnieli A,Fereres A,Weintraub PG

更新日期：2010-03-01 00:00:00

abstract：:The cellular uptake, localization and efflux of meso-tetra-(4-hydroxyphenyl)porphyrin (p-THPP)-loaded nanoparticles have been studied in EMT-6 tumor cells. The effect of blood serum on photocytotoxicity has also been evaluated. Sub-130 nm nanoparticles based on poly(D,L-lactide-co-glycolide) (PLGA) (50:50 PLGA and 75:...

journal_title：Photochemistry and photobiology

authors： Konan YN,Chevallier J,Gurny R,Allémann E

更新日期：2003-06-01 00:00:00

abstract：:A widely published expression for dipole strengths of optical transitions is found to require correction. The proposed adjustment, which involves the refractive index of the solvent in which the strengths are measured, may lead to significant changes in predictions that have been based on the equation. We discuss a cl...

journal_title：Photochemistry and photobiology

authors： Knox RS

更新日期：2003-05-01 00:00:00

abstract：:In the present study, photodynamic activity of a novel photosensitizer (PS), Chlorin e(6)-2.5 N-methyl-d-glucamine (BLC 1010), was evaluated using the chorioallantoic membrane (CAM) as an in vivo model. After intravenous (i.v.) injection of BLC 1010 into the CAM vasculature, the applicability of this drug for photodyn...

journal_title：Photochemistry and photobiology

authors： Pegaz B,Debefve E,Borle F,Ballini JP,Wagnières G,Spaniol S,Albrecht V,Scheglmann D,Nifantiev NE,van den Bergh H,Konan YN

更新日期：2005-11-01 00:00:00

abstract：:Ultraviolet photolesions endow DNA with distinct structural and dynamic properties. Biophysical studies of photoproduct-containing DNA have shown that these lesions affect the mutagenic properties of DNA and damage recognition by DNA repair systems. Recently obtained high-resolution cocrystal structures of damaged DNA...

journal_title：Photochemistry and photobiology

authors： Park CJ,Lee JH,Choi BS

更新日期：2007-01-01 00:00:00

abstract：:High intensity two-photon picosecond excitation at 266 nm (effective energy 9.2 eV) has been shown to cause efficient photolysis of thymine in aqueous solution. Experimental results for the quantum yield of solvated electrons, phi (eaq-), and the net consumption of thymine, phi(-Thy) have been interpreted (Oraevsky an...

journal_title：Photochemistry and photobiology

authors： Daniels M

更新日期：1991-07-01 00:00:00

abstract：:Vitamin A palmitate has been used in cosmetics; however, studies report that this substance shows photoreactivity that can lead to loss of safety and efficacy. On the other hand, photostabilizers have been used to increase sunscreen photostability and consequently their safety and effectiveness. Thus, this study aimed...

journal_title：Photochemistry and photobiology

authors： Benevenuto CG,Di Matteo MA,Maia Campos PM,Gaspar LR

更新日期：2010-11-01 00:00:00

abstract：:Raman spectroscopy (RS) has potential for disease classification within the gastrointestinal tract (GI). A near-infrared (NIR) fiber-optic RS system has been developed previously. This study reports the first in vivo Raman spectra of human gastrointestinal tissues measured during routine clinical endoscopy. This was a...

journal_title：Photochemistry and photobiology

authors： Shim MG,Song LM,Marcon NE,Wilson BC

更新日期：2000-07-01 00:00:00

abstract：:Our recent study follows up an earlier one which demonstrated hypericin-mediated photocytotoxic effects on HT-29 adenocarcinoma cells by light fractionation with a longer dark pause between two unequal light doses (Sackova, A. [2005] Photochem. Photobiol.81, 1411-1416). Here, we present closer study on events invoked ...

journal_title：Photochemistry and photobiology

authors： Kuliková L,Mikeš J,Hýžďalová M,Palumbo G,Fedoročko P

更新日期：2010-11-01 00:00:00

abstract：:The biguanide metformin is widely used for the treatment of Type-II diabetes. Its antiproliferative and pro-apoptotic effects in various tumor cells suggest its potential candidacy for cancer chemoprevention. Herein, we report that metformin significantly inhibited human epidermoid A431 tumor xenograft growth in nu/nu...

journal_title：Photochemistry and photobiology

authors： Chaudhary SC,Kurundkar D,Elmets CA,Kopelovich L,Athar M

更新日期：2012-09-01 00:00:00

abstract：:In order to gain insight into the preactivation of merocyanine 540 (MC540) 1 for the photodynamic therapy (Gulliya et al., 1990a, Photochem. Photobiol. 52, 831-838) its photo-oxidation was investigated. After irradiation of MC540 1 on a preparative scale three main photodegradation products were isolated with 16-20% y...

journal_title：Photochemistry and photobiology

authors： Franck B,Schneider U

更新日期：1992-08-01 00:00:00