In vitro photodynamic effects of lysyl chlorin p6: cell survival, localization and ultrastructural changes.

abstract：:The UV radiation environment on planetary surfaces and within atmospheres is of importance in a wide range of scientific disciplines. Solar UV radiation is a driving force of chemical and organic evolution and serves also as a constraint in biological evolution. In this work we modeled the transmission of present and ...

journal_title：Photochemistry and photobiology

authors： Rontó G,Bérces A,Lammer H,Cockell CS,Molina-Cuberos GJ,Patel MR,Selsis F

更新日期：2003-01-01 00:00:00

abstract：:Identification of natural products capable of affording protection against UVB radiation-induced inflammatory responses and generation of oxidative stress may have important human health implications. The UVB exposure-induced skin injury and oxidative stress has been associated with a variety of skin disease condition...

journal_title：Photochemistry and photobiology

authors： Katiyar SK,Matsui MS,Elmets CA,Mukhtar H

更新日期：1999-02-01 00:00:00

abstract：:Unidirectional blue light directs the rhizoid-thallus axis in the apolar zygote of the brown alga, Silvetia compressa. This effect is mediated by an increase in the intracellular concentration of guanosine 3', 5'-cyclic monophosphate. In this study we show the identification of a rhodopsin-like protein, by means of an...

journal_title：Photochemistry and photobiology

authors： Gualtieri P,Robinson KR

更新日期：2002-01-01 00:00:00

abstract：:Although histochemical and immunohistochemical methods are the standard procedures in diagnosis of lymphoproliferative disorders, useful improvements in evidencing histopathologic manifestations can be obtained with the introduction of tissue autofluorescence analyses. We used microspectrofluorometry and a Multispectr...

journal_title：Photochemistry and photobiology

authors： Rigacci L,Alterini R,Bernabei PA,Ferrini PR,Agati G,Fusi F,Monici M

更新日期：2000-06-01 00:00:00

abstract：:The thermodynamics of binding of Me-alpha(-GalNAc, Gal-beta-1-3GalNAc-alpha-O-Me (T-antigen-alpha), Gal-beta-1-3GalNAc and Gal-alpha-1-6Glc (mellibiose) to Artocarpus hirsuta lectin was studied using fluorescence spectroscopy. The binding affinities of the saccharides are in the order Gal-beta-1-3GalNAc-alpha-O-Me > M...

journal_title：Photochemistry and photobiology

authors： Gaikwad SM,Khan MI

更新日期：2006-09-01 00:00:00

abstract：:Confocal laser microspectrofluorometric measurements on human T47D mammary tumor cells have been performed to assess the intracellular distribution of hypericin within the various cell compartments: cytoplasmic membrane, cytoplasm and nucleus. Confocal fluorescence measurements obtained from microvolumes (approximatel...

journal_title：Photochemistry and photobiology

authors： Miskovsky P,Sureau F,Chinsky L,Turpin PY

更新日期：1995-09-01 00:00:00

abstract：:To improve the understanding of human skin autofluorescence emission, the spectroscopic and microscopic characteristics of skin autofluorescence were studied using a combined fluorescence and reflectance spectroanalyzer and a fiber optic microspectrophotometer. The autofluorescence spectra of in vivo human skin were m...

journal_title：Photochemistry and photobiology

authors： Zeng H,MacAulay C,McLean DI,Palcic B

更新日期：1995-06-01 00:00:00

abstract：:This work evaluated the photoprotective and antigenotoxic effects against ultraviolet B (UVB) radiation of flavonoid compounds apigenin, naringenin and pinocembrin. The photoprotective efficacy of these compounds was estimated using in vitro photoprotection indices, and the antigenotoxicity against UVB radiation was e...

journal_title：Photochemistry and photobiology

authors： García Forero A,Villamizar Mantilla DA,Núñez LA,Ocazionez RE,Stashenko EE,Fuentes JL

更新日期：2019-07-01 00:00:00

abstract：:Spatio-temporal patterns in sun exposure underlie variations in skin cancer incidence and vitamin D deficiency, indicate effectiveness of sun protection programs and provide insights into future health risks. From 558 adults across four regions of Australia (Brisbane (27°S), Newcastle (33°S), Geelong and the Western D...

journal_title：Photochemistry and photobiology

authors： Lucas RM,Valery P,van der Mei I,Dwyer T,Pender MP,Taylor B,Ponsonby AL,Ausimmune Investigator Group.

更新日期：2013-05-01 00:00:00

abstract：:Uveal melanoma is the most frequent intraocular cancer and the second most common form of melanoma. It metastasizes in half of the patients and the prognostic is poor. Although ultraviolet (UV) radiation is a proven risk factor for skin melanoma, the role of UV light in the etiology of uveal melanoma is still contradi...

journal_title：Photochemistry and photobiology

authors： Mallet JD,Gendron SP,Drigeard Desgarnier MC,Rochette PJ

更新日期：2014-01-01 00:00:00

abstract：:A polyclonal, multispecific antiserum was raised against a whole 3[(3-cholamidopropyl)-dimethylammonio]-1-propanesulfonate-extract of nonirradiated Blepharisma japonicum cells. It was used to reveal the composition of solutions that were hypothesized to contain the photoreceptor of the ciliate. A Bio-Gel A 1.5 m fine ...

journal_title：Photochemistry and photobiology

authors： Podestà A,Gioffré D,Grossi T,Montagnoli G

更新日期：2000-05-01 00:00:00

abstract：:Photodynamic treatment is often thought to produce reactive oxygen species (ROS) that directly induce killing; the nomenclature and phrases revolve around such notions of light-dependency. Few studies reference the possible existence of oxidation products formed in secondary reactions, which bear cytotoxicity competit...

journal_title：Photochemistry and photobiology

authors： Chiemezie C,Greer A

更新日期：2019-01-01 00:00:00

abstract：:Photosensitized protein cross-linking has been recently developed to seal wounds and strengthen tissue. Although the photosensitizing dye, Rose Bengal (RB), is phototoxic to cultured cells, cytotoxicity does not accompany RB-photosensitized tissue repair in vivo. We investigated whether the environment surrounding cel...

journal_title：Photochemistry and photobiology

authors： Yao M,Gu C,Doyle FJ Jr,Zhu H,Redmond RW,Kochevar IE

更新日期：2014-03-01 00:00:00

abstract：:In cultured human keratinocytes, the tumor suppressor p53 acts as a control element in the protective response to UVB radiation and is affected by a variety of factors linked to cellular adhesion and differentiation. Because keratinocytes within the epidermis are not a homogeneous population but differ in their prolif...

journal_title：Photochemistry and photobiology

authors： Will K,Neben M,Schmidt-Rose T,Deppert W,Wittern KP,Bergemann J

更新日期：2000-03-01 00:00:00

abstract：:To clarify the role of the Golgi apparatus in photodynamic therapy-induced apoptosis, its signaling pathway was studied after photodynamic treatment of human cervix carcinoma cell line HeLa, in which a photosensitizer, 2,4,5,7-tetrabromorhodamine 123 bromide (TBR), was incorporated into the Golgi apparatus. Laser scan...

journal_title：Photochemistry and photobiology

authors： Ogata M,Inanami O,Nakajima M,Nakajima T,Hiraoka W,Kuwabara M

更新日期：2003-09-01 00:00:00

abstract：:The photoinduced covalent binding of the title compound to native and heat denatured DNA is described. The level of binding has been measured by UV (for DNA) and atomic absorption (for Rh) analysis. Quantum efficiencies of 6.4 x 10(-4) mol Rh per mol photons and 1.6 x 10(-3) mol Rh per mol photons have been determined...

journal_title：Photochemistry and photobiology

authors： Mahnken RE,Bina M,Deibel RM,Luebke K,Morrison H

更新日期：1989-04-01 00:00:00

abstract：:The efficiency of ruthenium complexes for photosensitizing DNA damage depends on the oxidizing character of their ligands. Here we report on the difference in behavior of tris(2.2'-bipyrazyl)ruthenium(II) (Ru[bpz]3(2+)), tris(2,2'-bipyridyl)ruthenium(II) (Ru[bipy]3(2+)) and cis-dichlorobis (2,2'-bipyrazyl)ruthenium(II...

journal_title：Photochemistry and photobiology

authors： Vicendo P,Mouysset S,Paillous N

更新日期：1997-04-01 00:00:00

abstract：:Herpes simplex virus (HSV) normally causes vescular lesions on mucocutaneous surfaces but can also cause encephalitis. The virus can reactivate from the latent state in neurons to form recrudescent lesions. One common stimulus for reactivation is exposure to sunlight. In the present study, the effects of irradiating r...

journal_title：Photochemistry and photobiology

authors： Garssen J,van der Molen R,de Klerk A,Norval M,van Loveren H

更新日期：2000-11-01 00:00:00

abstract：:Systemic injection of hematoporphyrin derivative (HpD) in contribution with visible light (red or blue-green) delivered by laser was used to treat a patient with psoriasis. The psoriatic lesions responded vigorously to laser treatments, forming eschars by 1 week post irradiation. In contrast, only minimal erythema was...

journal_title：Photochemistry and photobiology

authors： McCullough JL,Weinstein GD,Douglas JL,Berns MW

更新日期：1987-07-01 00:00:00

abstract：:The capacity of some linear and angular furocoumarins to induce DNA-protein cross-links by UVA (320-400 nm) irradiation has been evaluated in Chinese hamster ovary cells. Two linear furocoumarins, psoralen and 8-methoxypsoralen appeared to be capable of inducing DNA-protein cross-links to a noticeable extent. 4'-Methy...

journal_title：Photochemistry and photobiology

authors： Bordin F,Carlassare F,Busulini L,Baccichetti F

更新日期：1993-07-01 00:00:00

abstract：:The recently discovered photo-activated adenylyl cyclase (mPAC from Microcoleus chthonoplastes) is the first PAC that owes a light-, oxygen- and voltage-sensitive (LOV) domain for blue-light sensing. The photoreaction of the mPAC receptor was studied by time-resolved UV/vis and light-induced Fourier transform infrared...

journal_title：Photochemistry and photobiology

authors： Kerruth S,Langner P,Raffelberg S,Gärtner W,Heberle J

更新日期：2017-05-01 00:00:00

abstract：:Collagen was exposed to an ultraviolet (UV) lamp that emitted predominantly in the UVB range. The cross-linking of collagen type I and type IV by UV irradiation was observed. Amino acid analyses revealed that Tyr residues in both collagen types I and IV were decreased by irradiation. In collagen type IV, losses of His...

journal_title：Photochemistry and photobiology

authors： Kato Y,Nishikawa T,Kawakishi S

更新日期：1995-04-01 00:00:00

abstract：:Photoisomerization of a protein-bound chromophore is the basis of light sensing and signaling in many photoreceptors. Phytochrome photoreceptors can be photoconverted reversibly between the Pr and Pfr states through photoisomerization of the methine bridge between rings C and D. Ground-state heterogeneity of the chrom...

journal_title：Photochemistry and photobiology

authors： Stensitzki T,Yang Y,Wölke AL,Knapp EW,Hughes J,Mroginski MA,Heyne K

更新日期：2017-05-01 00:00:00

abstract：:All-trans retinoic acid (ATRA) plays essential roles in the normal biological processes and the treatment of cancer and skin diseases. Considering its photosensitive property, many studies have been focused on the photochemistry of ATRA. In this study, we investigated the transient phenomena in the laser flash photoly...

journal_title：Photochemistry and photobiology

authors： Li K,Wang M,Wang T,Sun D,Zhu R,Sun X,Wu X,Wang SL

更新日期：2013-09-01 00:00:00

abstract：:Cumulative and intermittent sun exposure are risk factors for skin cancer, highlighting the need to monitor exposure during childhood. There is currently very little available information concerning the accuracy of self-reported levels of sun exposure, particularly for very young children. In this study, UV radiation ...

journal_title：Photochemistry and photobiology

authors： O'Riordan DL,Stanton WR,Eyeson-Annan M,Gies P,Roy C

更新日期：2000-01-01 00:00:00

abstract：:The effect of pretreatment with vitamin E on cytotoxicity, DNA single strand breaks, and chromosomal aberrations as well as on mutation induced by ultraviolet-B light (UV-B) was investigated in Chinese hamster V-79 cells. Cellular pretreatment with non-toxic levels of 25 microM alpha-tocopherol succinate (vitamin E) f...

journal_title：Photochemistry and photobiology

authors： Sugiyama M,Tsuzuki K,Matsumoto K,Ogura R

更新日期：1992-07-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00

abstract：:Photodamage to the endoplasmic reticulum (ER) can initiate a death pathway termed paraptosis. The "canonical" model of paraptosis, initiated by certain drugs and other stimuli, requires a brief interval of protein synthesis, involves the action of MAP kinases and can be followed by biochemical markers. The latter incl...

journal_title：Photochemistry and photobiology

authors： Kessel D

更新日期：2020-09-01 00:00:00

abstract：:Our recent study follows up an earlier one which demonstrated hypericin-mediated photocytotoxic effects on HT-29 adenocarcinoma cells by light fractionation with a longer dark pause between two unequal light doses (Sackova, A. [2005] Photochem. Photobiol.81, 1411-1416). Here, we present closer study on events invoked ...

journal_title：Photochemistry and photobiology

authors： Kuliková L,Mikeš J,Hýžďalová M,Palumbo G,Fedoročko P

更新日期：2010-11-01 00:00:00

abstract：:In recent years the class of known fluorescent proteins (FPs) has dramatically expanded as an ever-increasing numbers of variants and homologs of the green fluorescent protein (GFP) from Aequorea jellyfish have been either engineered in the lab or discovered in other marine organisms. The red fluorescent protein (RFP)...

journal_title：Photochemistry and photobiology

authors： Li Y,Sierra AM,Ai HW,Campbell RE

更新日期：2008-01-01 00:00:00