Performance of a lookup table-based approach for measuring tissue optical properties with diffuse optical spectroscopy.

abstract：:Fluorescence spectroscopy is a promising technology for detection of epithelial precancers and cancers. While age and menopausal status influence measurements in the cervix, other variables do not significantly affect the diagnosis. In this study we examine probe pressure as a variable. A fiber optic probe to measure ...

journal_title：Journal of biomedical optics

authors： Nath A,Rivoire K,Chang S,Cox D,Atkinson EN,Follen M,Richards-Kortum R

更新日期：2004-05-01 00:00:00

abstract：:Cardiac architecture is inherently three-dimensional, yet most characterizations rely on two-dimensional histological slices or dissociated cells, which remove the native geometry of the heart. We previously developed a method for labeling intact heart sections without dissociation and imaging large volumes while pres...

journal_title：Journal of biomedical optics

authors： Huang H,Macgillivray C,Kwon HS,Lammerding J,Robbins J,Lee RT,So P

更新日期：2009-07-01 00:00:00

abstract：:The authors' aim is to assess and quantitatively measure brain hemodynamic and morphological variations during closed-head injury (CHI) in mice using orthogonal diffuse near-infrared reflectance spectroscopy (o-DRS). CHI is a type of injury to the head that does not penetrate the skull. Usually, it is caused by mechan...

journal_title：Journal of biomedical optics

authors： Abookasis D,Shochat A,Mathews MS

更新日期：2013-04-01 00:00:00

abstract：:Smart toilets could be used to monitor different components of urine in daily life for early detection of lifestyle-related diseases and prompt provision of treatment. For analysis of biological samples such as urine by midinfrared spectroscopy, thin-film samples like liquid cells are needed because of the strong abso...

journal_title：Journal of biomedical optics

authors： Yamamoto N,Kawashima N,Kitazaki T,Mori K,Kang H,Nishiyama A,Wada K,Ishimaru I

更新日期：2018-05-01 00:00:00

abstract：:Lucigenin- and luminol-dependent chemiluminescence [(LC-CL) and (LM-CL)] in nondiluted human blood was studied. LM-CL was low in fresh blood and disappeared after its storage for 3 h, though the respiratory burst (RB) stimulation in blood was followed by high intensity and long-lasting LM-CL. LC-CL was high in fresh b...

journal_title：Journal of biomedical optics

authors： Voeikov VL,Novikov CN,Vilenskaya ND

更新日期：1999-01-01 00:00:00

abstract：:Utilizing a laser scanning confocal microscope system, the refractive indices of articular cartilage (AC) with mechanical or biochemical degenerations were characterized to investigate whether potential correlations exist between refractive index (RI) and cartilage degeneration. The cartilage samples collected from th...

journal_title：Journal of biomedical optics

authors： Wang K,Wu J,Day R,Kirk TB,Hu X

更新日期：2016-09-01 00:00:00

abstract：:Ophthalmic surgery may benefit from use of more precise fiber delivery systems during laser surgery. Some current ophthalmic surgical techniques rely on tedious mechanical dissection of tissue layers. In this study, chains of sapphire microspheres integrated into a hollow waveguide distal tip are used for erbium:YAG l...

journal_title：Journal of biomedical optics

authors： Hutchens TC,Darafsheh A,Fardad A,Antoszyk AN,Ying HS,Astratov VN,Fried NM

更新日期：2012-06-01 00:00:00

abstract：:The epithelium (EP) thickness and the standard deviation (SD) of A-mode scan intensity in the laminar propria (LP) layer are used as effective indicators for the diagnosis of oral submucous fibrosis (OSF) based on the noninvasive clinical scanning of a swept-source optical coherence tomography (OCT) system of approxim...

journal_title：Journal of biomedical optics

authors： Lee CK,Tsai MT,Lee HC,Chen HM,Chiang CP,Wang YM,Yang CC

更新日期：2009-09-01 00:00:00

abstract：:Vectorial models of focused beams are important to a variety of fields including microscopy, lithography, optical physics, and biomedical imaging. This has led to many models being developed, which calculate how beams of various profiles are focused both in free space and in the presence of stratified media. The major...

journal_title：Journal of biomedical optics

authors： Munro PRT

更新日期：2018-09-01 00:00:00

abstract：:Full-field optical coherence tomography (FF-OCT) capable of in vivo cellular-level imaging is demonstrated for nonscanning horizontal cross-sectional imaging. The system is based on a white light interference microscope illuminated by a thermal light source. A dual-channel two-dimensional (2-D) detection technique inc...

journal_title：Journal of biomedical optics

authors： Akiba M,Chan KP

更新日期：2007-11-01 00:00:00

abstract：:Diffuse optical imaging is an effective technique for noninvasive functional brain imaging. However, the measurements respond to systemic hemodynamic fluctuations caused by the cardiac cycle, respiration, and blood pressure, which may obscure or overwhelm the desired stimulus-evoked response. Previous work on this pro...

journal_title：Journal of biomedical optics

authors： Zhang Y,Brooks DH,Franceschini MA,Boas DA

更新日期：2005-01-01 00:00:00

abstract：:The efficacy of existing therapies and the discovery of innovative treatments for central nervous system (CNS) diseases have been limited by the lack of appropriate methods to investigate complex molecular processes at the synaptic level. To improve our capability to investigate complex mechanisms of synaptic signalin...

journal_title：Journal of biomedical optics

authors： Labrecque S,Sylvestre JP,Marcet S,Mangiarini F,Bourgoin B,Verhaegen M,Blais-Ouellette S,De Koninck P

更新日期：2016-04-30 00:00:00

abstract：:Breast cancer is one of the most common cancers in females. To monitor chemotherapeutic efficacy for breast cancer, medical imaging systems such as x-ray mammography, computed tomography, magnetic resonance imaging, and ultrasound imaging have been used. Currently, it can take up to 3 to 6 weeks to see the tumor respo...

journal_title：Journal of biomedical optics

authors： Lee S,Jeong H,Seong M,Kim JG

更新日期：2017-12-01 00:00:00

abstract：:Cellular therapies hold promise to replace the implantation of whole organs in the treatment of disease. For most cell types, in vivo viability depends on oxygen delivery to avoid the toxic effects of hypoxia. A promising approach is the in situ vascularization of implantable devices which can mediate hypoxia and impr...

journal_title：Journal of biomedical optics

authors： Weidling J,Sameni S,Lakey JR,Botvinick E

更新日期：2014-08-01 00:00:00

abstract：:We present the first experimental result of direct delineation of the nuclei of living rat bladder epithelium with ultrahigh-resolution optical coherence tomography (uOCT). We demonstrate that the cellular details embedded in the speckle noise in a uOCT image can be uncovered by time-lapse frame averaging that takes a...

journal_title：Journal of biomedical optics

authors： Pan YT,Wu ZL,Yuan ZJ,Wang ZG,Du CW

更新日期：2007-09-01 00:00:00

abstract：:Cochlear implantation offers the potential to restore sensitive hearing in patients with severe to profound deafness. However, surgical placement of the electrode array within the cochlea can produce trauma to sensorineural components, particularly if the initial turn of the cochlea is not successfully navigated as th...

journal_title：Journal of biomedical optics

authors： Gurbani SS,Wilkening P,Zhao M,Gonenc B,Cheon GW,Iordachita II,Chien W,Taylor RH,Niparko JK,Kang JU

更新日期：2014-05-01 00:00:00

abstract：:We describe a computer eye model that allows for aspheric surfaces and a three-dimensional computer-based ray-tracing technique to simulate optical properties of the human eye and visual perception under various eye defects. Eye surfaces, such as the cornea, eye lens, and retina, are modeled or approximated by a set o...

journal_title：Journal of biomedical optics

authors： Fink W,Micol D

更新日期：2006-09-01 00:00:00

abstract：:This paper presents comprehensive and depth-resolved retinal microvasculature images within human retina achieved by a newly developed ultrahigh sensitive optical microangiography (UHS-OMAG) system. Due to its high flow sensitivity, UHS-OMAG is much more sensitive to tissue motion due to the involuntary movement of th...

journal_title：Journal of biomedical optics

authors： An L,Shen TT,Wang RK

更新日期：2011-10-01 00:00:00

abstract：:Pedicle screw (PS) fixation has been widely used for spine diseases. Scientists and clinicians employ several approaches to navigate PS during operation. We have demonstrated the feasibility of monitoring the reduced scattering coefficient (μ's) on the trajectory of PS using near-infrared spectroscopy (NIRS). To perfo...

journal_title：Journal of biomedical optics

authors： Liu Y,Wang Y,Qian Z,Zhao J,Cao X,Li W

更新日期：2014-01-01 00:00:00

abstract：:The measurement of changes in blood volume in tissue is important for monitoring the effects of a wide range of therapeutic interventions, from radiation therapy to skin-flap transplants. Many systems available for purchase are either expensive or difficult to use, limiting their utility in the clinical setting. A low...

journal_title：Journal of biomedical optics

authors： Glennie DL,Hayward JE,McKee DE,Farrell TJ

更新日期：2014-01-01 00:00:00

abstract：:Flow imaging is an important technique in a range of disease areas, but estimating low flow speeds, especially near the walls of blood vessels, remains challenging. Pulsed photoacoustic flow imaging can be an alternative since there is little signal contamination from background tissue with photoacoustic imaging. We p...

journal_title：Journal of biomedical optics

authors： van den Berg PJ,Daoudi K,Steenbergen W

更新日期：2016-02-01 00:00:00

abstract：UNLABELLED:Temperature changes caused by laser irradiation can promote damage to the surrounding dental tissues. In this study, we evaluated the temperature changes of recently extracted human mandibular incisors during intracanal irradiation with an 810-nm diode laser at different settings. Fifty mandibular incisors w...

journal_title：Journal of biomedical optics

authors： da Fonseca Alvarez A,Moura-Netto C,Daliberto Frugoli A,Fernando C,Aranha AC,Davidowicz H

更新日期：2012-01-01 00:00:00

abstract：:Multiphoton microscopy (MPM) has the capacity to record second-harmonic generation (SHG) and endogenous two-photon excitation fluorescence (2PEF) signals emitted from biological tissues. The development of fiber-based miniaturized endomicroscopes delivering pulses in the femtosecond range will allow the transfer of MP...

journal_title：Journal of biomedical optics

authors： Garofalakis A,Kruglik SG,Mansuryan T,Gillibert A,Thiberville L,Louradour F,Vever-Bizet C,Bourg-Heckly G

更新日期：2019-10-01 00:00:00

abstract：:Studies of bioluminescence in living animals, such as cell-based biosensor applications, require measurement of light at different wavelengths, but accurate light measurement is impeded by absorption by tissues at wavelengths<600 nm. We present a novel approach to this problem--the use of a plastic window in the skin/...

journal_title：Journal of biomedical optics

authors： Huang Q,Acha V,Yow R,Schneider E,Sardar DK,Hornsby PJ

更新日期：2007-09-01 00:00:00

abstract：:The erratum concerns amendment of Section 2.5 of the published article. ...

journal_title：Journal of biomedical optics

authors： Hu XS,Arredondo MM,Gomba M,Confer N,DaSilva AF,Johnson TD,Shalinsky M,Kovelman I

更新日期：2020-05-01 00:00:00

abstract：:A transgenic mouse model with a Clim [co-factor of LIM (a combination of first letters of Lin-11 (C. elegans), ISL1 (rat), and Mec-3 (C. elegans) gene names) domain proteins] gene partially blocked in the epithelial compartment of its tissues is used to establish the sensitivity of intrinsic reflectance nonlinear opti...

journal_title：Journal of biomedical optics

authors： Lyubovitsky JG,Spencer JA,Krasieva TB,Andersen B,Tromberg BJ

更新日期：2006-01-01 00:00:00

abstract：:Muscle blood flow (MBF) and muscle oxygen saturation (SmO(2)) were measured at eight locations (four proximal, four distal) over a 4 x 8 cm(2) area of the vastus lateralis at rest and immediately after isometric, maximal quadriceps contraction using multichannel, frequency-domain, near-infrared spectroscopy. A venous ...

journal_title：Journal of biomedical optics

authors： Quaresima V,Ferrari M,Franceschini MA,Hoimes ML,Fantini S

更新日期：2004-03-01 00:00:00

abstract：:Treatment of deep venous thrombosis (DVT)--a primary cause of potentially fatal pulmonary embolism (PE)--depends on the age of the thrombus. The existing clinical imaging methods are capable of visualizing a thrombus but cannot determine the age of the blood clot. Therefore, there is a need for an imaging technique to...

journal_title：Journal of biomedical optics

authors： Karpiouk AB,Aglyamov SR,Mallidi S,Shah J,Scott WG,Rubin JM,Emelianov SY

更新日期：2008-09-01 00:00:00

abstract：SIGNIFICANCE:The potential of fluorescence lifetime imaging microscopy (FLIM) is recently being recognized, especially in biological studies. However, FLIM does not directly measure the lifetimes, rather it records the fluorescence decay traces. The lifetimes and/or abundances have to be estimated from these traces dur...

journal_title：Journal of biomedical optics

authors： Guo S,Silge A,Bae H,Tolstik T,Meyer T,Matziolis G,Schmitt M,Popp J,Bocklitz T

更新日期：2021-01-01 00:00:00

abstract：:An evolving area of biomedical research is related to the creation of implantable units that provide various possibilities for imaging, measurement, and the monitoring of a wide range of diseases and intrabody phototherapy. The units can be autonomic or built-in in some kind of clinically applicable implants. Because ...

journal_title：Journal of biomedical optics

authors： Sheinman V,Rudnitsky A,Toichuev R,Eshiev A,Abdullaeva S,Egemkulov T,Zalevsky Z

更新日期：2014-01-01 00:00:00