Low-level chemiluminescent analysis of nondiluted human blood reveals its dynamic system properties.

Abstract:

:Lucigenin- and luminol-dependent chemiluminescence [(LC-CL) and (LM-CL)] in nondiluted human blood was studied. LM-CL was low in fresh blood and disappeared after its storage for 3 h, though the respiratory burst (RB) stimulation in blood was followed by high intensity and long-lasting LM-CL. LC-CL was high in fresh blood and was steadily increasing with blood storage. Blood dilution with saline resulted in LC-CL attenuation and LM-CL elevation. LC-CL did not depend on air supply to blood, while LM-CL elevation during RB needed constant blood aeration. The results suggest that besides a well-known mechanism of reactive oxygen species production by neutrophils during RB, another process of electron excited state generation reflected by LC-CL operates in blood. It needs blood integrity for its manifestation and uses oxygen supplied by erythrocytes. Dynamic system properties of blood were revealed also in experiments with blood transfer from one sample to another in the course of RB. Highly nonlinear changes of CL intensity both in a "donor" and in a "recipient" sample resulted in strong differences in CL levels in two samples, one of which was prepared by blood subtraction, and another by blood addition. We suggest that CL data from measurements on nondiluted blood may be informative of integrative properties of blood tissue in addition to its being a measure of some sort of oxidative metabolism in it. © 1999 Society of Photo-Optical Instrumentation Engineers.

journal_name

J Biomed Opt

authors

Voeikov VL,Novikov CN,Vilenskaya ND

doi

10.1117/1.429921

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

54-60

issue

1

eissn

1083-3668

issn

1560-2281

pii

1101237

journal_volume

4

pub_type

杂志文章
  • Dual/differential coherent anti-Stokes Raman scattering module for multiphoton microscopes with a femtosecond Ti:sapphire oscillator.

    abstract::In the last decade, coherent anti-Stokes Raman scattering (CARS) microscopy has emerged as a powerful multiphoton imaging technique offering label-free chemical sensitivity and high three-dimensional resolution. However, its widespread application in the life sciences has been hampered by the use of costly pulsed lase...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.18.6.066004

    authors: Li B,Borri P,Langbein W

    更新日期:2013-06-01 00:00:00

  • Fast spatiotemporal image reconstruction based on low-rank matrix estimation for dynamic photoacoustic computed tomography.

    abstract::In order to monitor dynamic physiological events in near-real time, a variety of photoacoustic computed tomography (PACT) systems have been developed that can rapidly acquire data. Previously reported studies of dynamic PACT have employed conventional static methods to reconstruct a temporally ordered sequence of imag...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.19.5.056007

    authors: Wang K,Xia J,Li C,Wang LV,Anastasio MA

    更新日期:2014-05-01 00:00:00

  • Diagnostic performance of receptor-specific surgical specimen staining correlates with receptor expression level.

    abstract::Intraoperative margin assessment is imperative to cancer cure but is a continued challenge to successful surgery. Breast conserving surgery is a relevant example, where a cosmetically improved outcome is gained over mastectomy, but re-excision is required in >25  %   of cases due to positive or closely involved margin...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.24.2.026002

    authors: Schaefer JM,Barth CW,Davis SC,Gibbs SL

    更新日期:2019-02-01 00:00:00

  • Practicability and safety of laser-assisted reduction surgery.

    abstract::We have presented an innovative laser-assisted reduction surgery (LARS) based on plasma-induced ablation and photodisruption effects. In addition, we developed a laser operation system. Fetuses of mice from the Institute for Cancer Research that were immersed in physiological saline were irradiated by convergent-pulse...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.18.11.118002

    authors: Wang Y,Xiong Q,Ye Z,Ge J

    更新日期:2013-11-01 00:00:00

  • Unsupervised analysis of small animal dynamic Cerenkov luminescence imaging.

    abstract::Clustering analysis (CA) and principal component analysis (PCA) were applied to dynamic Cerenkov luminescence images (dCLI). In order to investigate the performances of the proposed approaches, two distinct dynamic data sets obtained by injecting mice with (32)P-ATP and (18)F-FDG were acquired using the IVIS 200 optic...

    journal_title:Journal of biomedical optics

    pub_type: 信件

    doi:10.1117/1.3663442

    authors: Spinelli AE,Boschi F

    更新日期:2011-12-01 00:00:00

  • Optical reflectance assay for the detection of biofilm formation.

    abstract::We describe the protocol for an inexpensive and nondestructive optical reflectance assay for the measurement of biofilm formation. Reflectance data are obtained using an Ocean Optics (Dunedin, Florida) USB 2000 spectrometer with a polychromatic light source. A fiber optic cable is used both for illumination and collec...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.1953347

    authors: Broschat SL,Loge FJ,Peppin JD,White D,Call DR,Kuhn E

    更新日期:2005-07-01 00:00:00

  • Accurate single-shot quantitative phase imaging of biological specimens with telecentric digital holographic microscopy.

    abstract::The advantages of using a telecentric imaging system in digital holographic microscopy (DHM) to study biological specimens are highlighted. To this end, the performances of nontelecentric DHM and telecentric DHM are evaluated from the quantitative phase imaging (QPI) point of view. The evaluated stability of the micro...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.19.4.046022

    authors: Doblas A,Sánchez-Ortiga E,Martínez-Corral M,Saavedra G,Garcia-Sucerquia J

    更新日期:2014-04-01 00:00:00

  • Micro-Raman spectroscopy study of cancerous and normal nasopharyngeal tissues.

    abstract::The capabilities of micro-Raman spectroscopy for differentiating normal and malignant nasopharyngeal tissues were evaluated. Raman scattering signals were acquired from 22 normal and 52 malignant nasopharyngeal tissue samples. Distinctive spectral differences in Raman spectra between normal and malignant nasopharyngea...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.18.2.027003

    authors: Li Y,Pan J,Chen G,Li C,Lin S,Shao Y,Feng S,Huang Z,Xie S,Zeng H,Chen R

    更新日期:2013-02-01 00:00:00

  • Navigation of a robot-integrated fluorescence laparoscope in preoperative SPECT/CT and intraoperative freehand SPECT imaging data: a phantom study.

    abstract::Robot-assisted laparoscopic surgery is becoming an established technique for prostatectomy and is increasingly being explored for other types of cancer. Linking intraoperative imaging techniques, such as fluorescence guidance, with the three-dimensional insights provided by preoperative imaging remains a challenge. Na...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.21.8.086008

    authors: van Oosterom MN,Engelen MA,van den Berg NS,KleinJan GH,van der Poel HG,Wendler T,van de Velde CJ,Navab N,van Leeuwen FW

    更新日期:2016-08-01 00:00:00

  • Effect of noise on modulation amplitude and phase in frequency-domain diffusive imaging.

    abstract::We theoretically investigate the effect of noise on frequency-domain heterodyne and/or homodyne measurements of intensity-modulated beams propagating through diffusive media, such as a photon density wave. We assumed that the attenuated amplitude and delayed phase are estimated by taking the Fourier transform of the n...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.17.1.016010

    authors: Kang D,Kupinski MA

    更新日期:2012-01-01 00:00:00

  • Correlation between asymmetry of spontaneous oscillation of hemodynamic changes in the prefrontal cortex and anxiety levels: a near-infrared spectroscopy study.

    abstract::According to the valence asymmetry hypothesis, the left/right asymmetry of prefrontal cortex (PFC) activity is correlated with specific emotional responses to mental stress and personality traits. Here, we evaluated the relation between emotional state and asymmetry in PFC activity at rest by using near-infrared spect...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.19.2.027005

    authors: Ishikawa W,Sato M,Fukuda Y,Matsumoto T,Takemura N,Sakatani K

    更新日期:2014-02-01 00:00:00

  • Theory and practical recommendations for autocorrelation-based image correlation spectroscopy.

    abstract::Image correlation spectroscopy (ICS) is a powerful technique for detecting arrangement of fluorophores in images. This tutorial gives background into the mathematical underpinnings of ICS, specifically image autocorrelation. The effects of various artifacts and image processing steps, including background subtraction,...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.17.8.080801

    authors: Robertson C,George SC

    更新日期:2012-08-01 00:00:00

  • New pediatric vision screener employing polarization-modulated, retinal-birefringence-scanning-based strabismus detection and bull's eye focus detection with an improved target system: opto-mechanical design and operation.

    abstract::Amblyopia ("lazy eye") is a major public health problem, caused by misalignment of the eyes (strabismus) or defocus. If detected early in childhood, there is an excellent response to therapy, yet most children are detected too late to be treated effectively. Commercially available vision screening devices that test fo...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.19.6.067004

    authors: Irsch K,Gramatikov BI,Wu YK,Guyton DL

    更新日期:2014-06-01 00:00:00

  • Hyperspectral wide gap second derivative analysis for in vivo detection of cervical intraepithelial neoplasia.

    abstract::Hyperspectral reflectance imaging technique has been used for in vivo detection of cervical intraepithelial neoplasia. However, the clinical outcome of this technique is suboptimal owing to multiple limitations such as nonuniform illumination, high-cost and bulky setup, and time-consuming data acquisition and processi...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.20.12.121303

    authors: Zheng W,Wang C,Chang S,Zhang S,Xu RX

    更新日期:2015-12-01 00:00:00

  • Bipolar cellular morphology of malignant melanoma in unstained human melanoma skin tissue.

    abstract::Microstructures of unstained human melanoma skin tissues have been examined by multimodal nonlinear optical microscopy. The polarized shape of the individual melanoma cell can be readily recognized-a phenotype that has been identified in laboratory cultures as characteristic of proliferating melanocytes but has not be...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.3120491

    authors: Zhang K,Zhang W,Yang CY,Yang H

    更新日期:2009-03-01 00:00:00

  • Infrared laser thermal fusion of blood vessels: preliminary ex vivo tissue studies.

    abstract::Suture ligation of blood vessels during surgery can be time-consuming and skill-intensive. Energy-based, electrosurgical, and ultrasonic devices have recently replaced the use of sutures and mechanical clips (which leave foreign objects in the body) for many surgical procedures, providing rapid hemostasis during surge...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.18.5.058001

    authors: Cilip CM,Rosenbury SB,Giglio N,Hutchens TC,Schweinsberger GR,Kerr D,Latimer C,Nau WH,Fried NM

    更新日期:2013-05-01 00:00:00

  • On the noninvasive optical monitoring and differentiation of methemoglobinemia and sulfhemoglobinemia.

    abstract::There are several pathologies whose study and diagnosis is impaired by a relatively small number of documented cases. A practical approach to overcome this obstacle and advance the research in this area consists in employing computer simulations to perform controlled in silico experiments. The results of these experim...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.17.9.097005

    authors: Baranoski GV,Chen TF,Kimmel BW,Miranda E,Yim D

    更新日期:2012-09-01 00:00:00

  • Dual closed-loop, optoelectronic, auto-oscillatory detection circuit for monitoring fluorescence lifetime-based chemical sensors and biosensors.

    abstract::We present a new detection instrument for sensor measurements based on excited-state fluorescence lifetimes. This system consists of a primary optoelectronic loop containing a resonance-type rf amplifier, a modulatable fluorescence-excitation light source, a fiber optic feedback loop (with a gap for a fluorescent sens...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.1688814

    authors: Rabinovich E,Sviminoshvilli T,O'Brien MJ,Brueck SR,Lopez GP

    更新日期:2004-05-01 00:00:00

  • Technical considerations in longitudinal multispectral small animal molecular imaging.

    abstract::In a previous study, we investigated physical methods to reduce whole-body, diet-related autofluorescence interference in several mouse strains through changes in animal diet. Measurements of mice with an in vivo multispectral imaging system over a 21-day period allowed for the quantification of concentration changes ...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.2799188

    authors: Bouchard MB,MacLaurin SA,Dwyer PJ,Mansfield J,Levenson R,Krucker T

    更新日期:2007-09-01 00:00:00

  • Monitoring the reduced scattering coefficient of bone tissues on the trajectory of pedicle screw placement using near-infrared spectroscopy.

    abstract::Pedicle screw (PS) fixation has been widely used for spine diseases. Scientists and clinicians employ several approaches to navigate PS during operation. We have demonstrated the feasibility of monitoring the reduced scattering coefficient (μ's) on the trajectory of PS using near-infrared spectroscopy (NIRS). To perfo...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.19.11.117002

    authors: Liu Y,Wang Y,Qian Z,Zhao J,Cao X,Li W

    更新日期:2014-01-01 00:00:00

  • Pediatric Vision Screener 2: pilot study in adults.

    abstract::Amblyopia is a form of visual impairment caused by ocular misalignment (strabismus) or defocus in an otherwise healthy eye. If detected early, the condition can be fully treated, yet over half of all children with amblyopia under age 5 escape detection. We developed a Pediatric Vision Screener (PVS) to detect amblyopi...

    journal_title:Journal of biomedical optics

    pub_type: 临床试验,杂志文章

    doi:10.1117/1.1805561

    authors: Nassif DS,Piskun NV,Gramatikov BI,Guyton DL,Hunter DG

    更新日期:2004-11-01 00:00:00

  • Human graft cornea and laser incisions imaging with micrometer scale resolution full-field optical coherence tomography.

    abstract::Micrometer scale resolution full-field optical coherence tomography (FF-OCT) is developed for imaging human graft corneas. Three-dimensional (3-D) images with ultrahigh resolution (respectively, 1 and 1.5 μm in the axial and transverse directions), comparable to traditional histological sections, are obtained allowing...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.3486544

    authors: Latour G,Georges G,Lamoine LS,Deumié C,Conrath J,Hoffart L

    更新日期:2010-09-01 00:00:00

  • Continuous monitoring of arthritis in animal models using optical imaging modalities.

    abstract::Given the several difficulties associated with histology, including difficulty in continuous monitoring, this study aimed to investigate the feasibility of optical imaging modalities—cross-polarization color (CPC) imaging, erythema index (EI) imaging, and laser speckle contrast (LSC) imaging—for continuous evaluation ...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.JBO.19.10.106010

    authors: Son T,Yoon HJ,Lee S,Jang WS,Jung B,Kim WU

    更新日期:2014-01-01 00:00:00

  • Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging.

    abstract::This work reviews our research during the past several years on time-resolved (TR) near-infrared diffuse optical tomography (DOT). Following an introduction of the measuring modes, two proposed schemes of image reconstruction in TR-DOT are described: one utilizes the full TR data, and the other, referred to as the mod...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章,评审

    doi:10.1117/1.2815724

    authors: Zhao H,Gao F,Tanikawa Y,Yamada Y

    更新日期:2007-11-01 00:00:00

  • Cutaneous melanin exhibiting fluorescence emission under near-infrared light excitation.

    abstract::Under ultraviolet and visible light excitation, melanin is essentially a nonfluorescent substance. This work reports our study on near-infrared (NIR) fluorescence properties of melanins, and explores potential applications of NIR fluorescence techniques for evaluating skin disorders involving melanin. The NIR fluoresc...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.2204007

    authors: Huang Z,Zeng H,Hamzavi I,Alajlan A,Tan E,McLean DI,Lui H

    更新日期:2006-05-01 00:00:00

  • Real-time intraoperative fluorescence imaging system using light-absorption correction.

    abstract::We present a novel fluorescence imaging system developed for real-time interventional imaging applications. The system implements a correction scheme that improves the accuracy of epi-illumination fluorescence images for light intensity variation in tissues. The implementation is based on the use of three cameras oper...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.3259362

    authors: Themelis G,Yoo JS,Soh KS,Schulz R,Ntziachristos V

    更新日期:2009-11-01 00:00:00

  • New method for evaluation of in vivo scattering and refractive index properties obtained with optical coherence tomography.

    abstract::Optical coherence tomography (OCT) provides more parameters than pure morphology does. In a recent paper [A. Knuettel and M. Boehlau-Godau, J. Biomed. Opt. 5(1) 83-92 (2000)] we have shown that the refractive index (RI) can be evaluated in a localized manner in skin tissue under in vivo conditions. Based on a theory, ...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.1647544

    authors: Knüttel A,Bonev S,Knaak W

    更新日期:2004-03-01 00:00:00

  • Closure of skin incisions by laser-welding with a combination of two near-infrared diode lasers: preliminary study for determination of optimal parameters.

    abstract::Laser welding has the potential to become an effective method for wound closure and healing without sutures. Closure of skin incisions by laser welding with a combination of two near-infrared lasers (980 and 1064 nm), was performed for the first time in this study. One centimeter long, full-thickness incisions were ma...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.3552648

    authors: Hu L,Lu Z,Wang B,Cao J,Ma X,Tian Z,Gao Z,Qin L,Wu X,Liu Y,Wang L

    更新日期:2011-03-01 00:00:00

  • Confocal reflectance and two-photon microscopy studies of a songbird skull for preparation of transcranial imaging.

    abstract::We present experiments and analyses of confocal reflectance and two-photon microscopy studies of zebra finch skull samples. The thin and hollow structure of these birds' skulls is quite translucent, which can allow in vivo transcranial two-photon imaging for brain activation monitoring. However, the skull structure is...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.3155522

    authors: Abi-Haidar D,Olivier T

    更新日期:2009-05-01 00:00:00

  • Using ultrahigh sensitive optical microangiography to achieve comprehensive depth resolved microvasculature mapping for human retina.

    abstract::This paper presents comprehensive and depth-resolved retinal microvasculature images within human retina achieved by a newly developed ultrahigh sensitive optical microangiography (UHS-OMAG) system. Due to its high flow sensitivity, UHS-OMAG is much more sensitive to tissue motion due to the involuntary movement of th...

    journal_title:Journal of biomedical optics

    pub_type: 杂志文章

    doi:10.1117/1.3642638

    authors: An L,Shen TT,Wang RK

    更新日期:2011-10-01 00:00:00