Abstract:
:Breast cancer is one of the most common cancers in females. To monitor chemotherapeutic efficacy for breast cancer, medical imaging systems such as x-ray mammography, computed tomography, magnetic resonance imaging, and ultrasound imaging have been used. Currently, it can take up to 3 to 6 weeks to see the tumor response from chemotherapy by monitoring tumor volume changes. We used near-infrared spectroscopy (NIRS) to predict breast cancer treatment efficacy earlier than tumor volume changes by monitoring tumor vascular reactivity during inhalational gas interventions. The results show that the amplitude of oxy-hemoglobin changes (vascular reactivity) during hyperoxic gas inhalation is well correlated with tumor growth and responded one day earlier than tumor volume changes after chemotherapy. These results may imply that NIRS with respiratory challenges can be useful in early detection of tumor and in the prediction of tumor response to chemotherapy.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Lee S,Jeong H,Seong M,Kim JGdoi
10.1117/1.JBO.22.12.121603subject
Has Abstractpub_date
2017-12-01 00:00:00pages
121603issue
12eissn
1083-3668issn
1560-2281pii
2644397journal_volume
22pub_type
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