Abstract:
:We introduce the concept of deliberate placement of absorbers to alter the average path of photons through tissue for a biomedical optical device. By changing the reflectivity of a needle that separates a source and detector, the average photon path through a turbid medium can be changed. Totally reflective needles have photon scattering density functions similar to a point source and detector in an infinite medium. An absorbing needle moves the average photon path of photons that reach the detector away from the needle. Thus, by modulating the reflectivity of the needle, it is possible to modify the sensitive volume, and simple tomography data should be possible. These results are confirmed by Monte Carlo simulations and experiment. Experiments include moving a black target relative to an optical "needle" and measuring the resulting intensity and phase lag of light reaching a detector at the distal end of the needle.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Simonson P,D'Amico E,Gratton Edoi
10.1117/1.2168167subject
Has Abstractpub_date
2006-01-01 00:00:00pages
014023issue
1eissn
1083-3668issn
1560-2281journal_volume
11pub_type
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