Water wavenumber calibration for visible light optical coherence tomography.

abstract：:Higher-order optical errors of the human eye are often responsible for reduced visual acuity in spite of an optimal spherical or cylindrical refraction. These optical aberrations are of natural origin or can result from operations in the eye that involve optical structures. The ocular aberrometer presented is based on...

journal_title：Journal of biomedical optics

authors： Mierdel P,Kaemmerer M,Mrochen M,Krinke HE,Seiler T

更新日期：2001-04-01 00:00:00

abstract：:Planar glass waveguides with a specific number of modes were fabricated by Ag(+)-Na(+) exchange in Schott SG11 glass. The effective refractive indices were determined using m-line spectroscopy in both s- and p-polarization. By using the reversed Wentzel-Kramers-Brillouin approximation, the index profiles were describe...

journal_title：Journal of biomedical optics

authors： Hassanzadeh A,Nitsche M,Armstrong S,Nabavi N,Harrison R,Dixon SJ,Langbein U,Mittler S

更新日期：2010-05-01 00:00:00

abstract：:Breast cancer is one of the most common cancers in females. To monitor chemotherapeutic efficacy for breast cancer, medical imaging systems such as x-ray mammography, computed tomography, magnetic resonance imaging, and ultrasound imaging have been used. Currently, it can take up to 3 to 6 weeks to see the tumor respo...

journal_title：Journal of biomedical optics

authors： Lee S,Jeong H,Seong M,Kim JG

更新日期：2017-12-01 00:00:00

abstract：:Red blood cell (RBC) anomalies are significant symptoms for identification of health disorders and several blood diseases, which involve the modification of the parameters and biophysical characteristics of such cells. The aim of this study is to measure the three-dimensional phase information of healthy RBCs and thei...

journal_title：Journal of biomedical optics

authors： Agarwal S,Kumar V,Shakher C

更新日期：2017-10-01 00:00:00

abstract：:Spatially resolved spectroscopy (SRS) allows the estimation of absolute tissue oxygen saturation, the ratio of oxygenated to total hemoglobin concentration, which may facilitate the comparison of results among patients. Eighty-two premature infants were included over two years. The cerebral tissue oxygenation index (c...

journal_title：Journal of biomedical optics

authors： Sorensen LC,Leung TS,Greisen G

更新日期：2008-11-01 00:00:00

abstract：:An approach to an established technique that is potentially applicable for a more comprehensive understanding of the electrical properties of red blood cells (RBCs) is presented. Using a high-intensity gradient laser trap, RBCs can be singly trapped and consequentially ionized. The subsequent dynamics of the ionized c...

journal_title：Journal of biomedical optics

authors： Kelley M,Cooper J,Devito D,Mushi R,Aguinaga MDP,Erenso DB

更新日期：2018-05-01 00:00:00

abstract：:We experimentally compare the performance and image contrast of spontaneous Raman and coherent Stokes Raman scattering microscopy. We demonstrate the differences between these techniques on a series of geometry-controlled samples that range in complexity from a point (array of tips) to one-dimensional (line grating) a...

journal_title：Journal of biomedical optics

authors： Kim H,Michaels CA,Bryant GW,Stranick SJ

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:Investigations of foveal aberrations assume circular pupils. However, the pupil becomes increasingly elliptical with increase in visual field eccentricity. We address this and other issues concerning peripheral aberration specification. METHODS:One approach uses an elliptical pupil similar to the actual pupil ...

journal_title：Journal of biomedical optics

authors： Charman WN,Mathur A,Scott DH,Hartwig A,Atchison DA

更新日期：2012-02-01 00:00:00

abstract：:We have presented an innovative laser-assisted reduction surgery (LARS) based on plasma-induced ablation and photodisruption effects. In addition, we developed a laser operation system. Fetuses of mice from the Institute for Cancer Research that were immersed in physiological saline were irradiated by convergent-pulse...

journal_title：Journal of biomedical optics

authors： Wang Y,Xiong Q,Ye Z,Ge J

更新日期：2013-11-01 00:00:00

abstract：:A new skin-imaging method, which was developed recently, gives an informative image data about skin moles by collecting scattered polarized light reflected from their tissue area at different wavelengths and polarizations. This method is called as optical rotational spectropolarimetric imaging (ORSI), which scans the ...

journal_title：Journal of biomedical optics

authors： Graham L,Yitzhaky Y,Abdulhalim I

更新日期：2013-11-01 00:00:00

abstract：:Lumpectomy coupled with radiation therapy and/or chemotherapy is commonly used to treat breast cancer patients. We are developing an enhanced thermal IR imaging technique that has the potential to provide real-time imaging to guide tissue excision during a lumpectomy by delineating tumor margins. This enhanced thermal...

journal_title：Journal of biomedical optics

authors： Case JR,Young MA,Dréau D,Trammell SR

更新日期：2015-11-01 00:00:00

abstract：:A miniature fiber optic spectrometer enclosed within a semipermeable (dialysis) membrane is proposed for in vivo interstitial sensing applications. The semipermeable membrane acts as a molecular filter, allowing only small molecules to pass through to the sampling volume. This filtering, in principle, should enable co...

journal_title：Journal of biomedical optics

authors： Blazkiewicz P,Blazkiewicz K,Verhaege A,Anissimov YG,Roberts MS,Zvyagin AV

更新日期：2006-01-01 00:00:00

abstract：:Fluorescence lifetime imaging microscopy (FLIM) using multiphoton excitation techniques is now finding an important place in quantitative imaging of protein-protein interactions and intracellular physiology. Recent developments in multiphoton FLIM methods are reviewed and a novel multiphoton FLIM system using a streak...

journal_title：Journal of biomedical optics

authors： Krishnan RV,Masuda A,Centonze VE,Herman B

更新日期：2003-07-01 00:00:00

abstract：:The present report addresses the application of surface plasmon resonance (SPR) phenomenon for urea sensing. The former promises a high sensitivity, label-free detection, and real-time information by monitoring the refractive index change at the metal–dielectric interface. In the present report, a highly sensitive ure...

journal_title：Journal of biomedical optics

authors： Paliwal A,Tomar M,Gupta V

更新日期：2016-08-01 00:00:00

abstract：:As molecular imaging moves towards lower detection limits, the elimination of endogenous background signals becomes imperative. We present a facile background-suppression technique that specifically segregates the signal from surface-enhanced Raman scattering (SERS)-active nanoparticles (NPs) from the tissue autofluor...

journal_title：Journal of biomedical optics

authors： Mallia RJ,McVeigh PZ,Veilleux I,Wilson BC

更新日期：2012-07-01 00:00:00

abstract：:An integrated miniature multi-modal microscope (4M device) for microendoscopy was built and tested. Imaging performance is evaluated and imaging results are presented for both fluorescence and reflectance samples. Images of biological samples show successful imaging of both thin layers of fixed cells prepared on a sli...

journal_title：Journal of biomedical optics

authors： Rogers JD,Landau S,Tkaczyk TS,Descour MR,Rahman MS,Richards-Kortum R,Kärkäinen AH,Christenson T

更新日期：2008-09-01 00:00:00

abstract：:A computer simulation called RHME (Retinal Heating in Moving Eye) is developed to simulate the heating pattern that occurs in the retina during a long-duration exposure to a continuous wave laser beam. The simulation takes into account eye movements that occur during a deliberate fixation. Due to the rapid (millisecon...

journal_title：Journal of biomedical optics

authors： Lund BJ

更新日期：2004-09-01 00:00:00

abstract：:The effect of sampling region size and tissue heterogeneity is examined using fluorescence histogram assessment in a rat prostate tumor model with benzoporphyrin derivative fluorophore. Spatial heterogeneity in the fluorescence signal occurs on both macroscopic and microscopic scales. The periphery of the tumor is mor...

journal_title：Journal of biomedical optics

authors： Pogue BW,Chen B,Zhou X,Hoopes PJ

更新日期：2005-07-01 00:00:00

abstract：:An autofluorescence lifetime wide-field imaging system that can generate contrast in underlying tissue structures of normal and malignant brain tissue samples with video rate acquisition and processing time is presented. Images of the investigated tissues were acquired with high resolution (∼35 μm) using an algorithm ...

journal_title：Journal of biomedical optics

authors： Papour A,Taylor Z,Sherman A,Sanchez D,Lucey G,Liau L,Stafsudd O,Yong W,Grundfest W

更新日期：2013-06-01 00:00:00

abstract：:Our long-term goal was to investigate the potential of incorporating redox imaging technique as a breast cancer (BC) diagnosis component to increase the positive predictive value of suspicious imaging finding and to reduce unnecessary biopsies and overdiagnosis. We previously found that precancer and cancer tissues in...

journal_title：Journal of biomedical optics

authors： Xu HN,Tchou J,Feng M,Zhao H,Li LZ

更新日期：2016-11-01 00:00:00

abstract：:Ultrasmall scale implants have recently attracted focus as valuable tools for monitoring both acute and chronic diseases. Semiconductor optical technologies are the key to miniaturizing these devices to the long-sought sub-mm scale, which will enable long-term use of these devices for medical applications. This can al...

journal_title：Journal of biomedical optics

authors： Mujeeb-U-Rahman M,Adalian D,Chang CF,Scherer A

更新日期：2015-09-01 00:00:00

abstract：:We investigate the feasibility of using diode laser gas spectroscopy for sinusitis diagnostics. We simulate light propagation using the Monte Carlo concept, as implemented by the Advanced Systems Analysis Program (ASAP) software. Simulations and experimental data are compared for a model based on two scattering bodies...

journal_title：Journal of biomedical optics

authors： Persson L,Kristensson E,Simonsson L,Svanberg S

更新日期：2007-09-01 00:00:00

abstract：:A modified spatial-temporal speckle correlation technique for operational assessment of structural changes in muscle tissues after slaughtering is considered. Coefficient of biological activity as a quantitative indicator of structural changes of biochemical processes in biological tissues is proposed. The experimenta...

journal_title：Journal of biomedical optics

authors： Maksymenko OP,Muravsky LI,Berezyuk MI

更新日期：2015-09-01 00:00:00

abstract：:A clinical need exists for low-cost and noninvasive imaging tools capable of detecting inflammation in the joints of inflammatory arthritis patients. Previous studies have reported an optical contrast between inflamed and noninflamed joints resulting from distinct absorption and scattering properties. Accurate classif...

journal_title：Journal of biomedical optics

authors： Lighter D,Filer A,Dehghani H

更新日期：2019-06-01 00:00:00

abstract：:We combine laser tweezers with custom computer tracking software and robotics to analyze the motility [swimming speed, VCL (curvilinear velocity), and swimming force in terms of escape laser power (Pesc)] and energetics [mitochondrial membrane potential (MP)] of individual sperm. Domestic dog sperm are labeled with a ...

journal_title：Journal of biomedical optics

authors： Nascimento JM,Shi LZ,Chandsawangbhuwana C,Tam J,Durrant B,Botvinick EL,Berns MW

更新日期：2008-01-01 00:00:00

abstract：:Image resolution and signal level in fluorescence microscopy through inhomogeneous turbid media consisting of scatterers of multiple sizes under single- (1p), two- (2p), and three-photon (3p) excitation have been investigated based on a modified Monte Carlo model. The effects of the size distribution and the concentra...

journal_title：Journal of biomedical optics

authors： Deng X,Gan X,Gu M

更新日期：2003-07-01 00:00:00

abstract：:We present unsupervised clustering methods for automatic grouping of human red blood cells (RBCs) extracted from RBC quantitative phase images obtained by digital holographic microscopy into three RBC clusters with regular shapes, including biconcave, stomatocyte, and sphero-echinocyte. We select some good features re...

journal_title：Journal of biomedical optics

authors： Ahmadzadeh E,Jaferzadeh K,Lee J,Moon I

更新日期：2017-07-01 00:00:00

abstract：:The specificity of molecular and functional photoacoustic (PA) images depends on the accuracy of the photoacoustic absorption spectroscopy. The PA signal is proportional to the product of the optical absorption coefficient and local light fluence; quantitative PA measurements of the optical absorption coefficient ther...

journal_title：Journal of biomedical optics

authors： Bauer AQ,Nothdurft RE,Erpelding TN,Wang LV,Culver JP

更新日期：2011-09-01 00:00:00

abstract：:To evaluate retinal perfusion in the human eye, a dual-wavelength confocal scanning laser ophthalmoscope (cSLO) was developed that provides spectral imaging of the fundus using a combination of red (670 nm) and near-infrared (810 nm) wavelengths. The image of the ocular fundus was analyzed to find out if quantitative ...

journal_title：Journal of biomedical optics

authors： Rasta SH,Manivannan A,Sharp PF

更新日期：2012-11-01 00:00:00

abstract：:Nanophotothermolysis with long laser pulses for treatment of scattered cancer cells and their clusters is introduced with the main focus on real-time monitoring of temperature dynamics inside and around individual cancer cells labeled with carbon nanotubes. This technique utilizes advanced time- and spatially-resolved...

journal_title：Journal of biomedical optics

authors： Biris AS,Boldor D,Palmer J,Monroe WT,Mahmood M,Dervishi E,Xu Y,Li Z,Galanzha EI,Zharov VP

更新日期：2009-03-01 00:00:00