Practicability and safety of laser-assisted reduction surgery.

abstract：:Most reconstruction algorithms used in photoacoustic tomography do not account for the effects of acoustic attenuation on the recorded signals. For experimental measurements made in biological tissue, the frequency dependent acoustic attenuation causes high frequency components of the propagating photoacoustic waves t...

journal_title：Journal of biomedical optics

authors： Treeby BE

更新日期：2013-03-01 00:00:00

abstract：:According to the valence asymmetry hypothesis, the left/right asymmetry of prefrontal cortex (PFC) activity is correlated with specific emotional responses to mental stress and personality traits. Here, we evaluated the relation between emotional state and asymmetry in PFC activity at rest by using near-infrared spect...

journal_title：Journal of biomedical optics

authors： Ishikawa W,Sato M,Fukuda Y,Matsumoto T,Takemura N,Sakatani K

更新日期：2014-02-01 00:00:00

abstract：:Alzheimer's disease (AD) is a neurodegenerative disorder that leads to a decline in cognitive and intellectual abilities and an irreversible mental deterioration. Based on multidisciplinary AD research, the most universally accepted hypotheses on AD pathogenesis are the intracerebral aggregate formation of beta-amyloi...

journal_title：Journal of biomedical optics

authors： Kim CB,Choi YY,Song WK,Song KB

更新日期：2014-05-01 00:00:00

abstract：:In near-infrared spectroscopy, concentration changes in oxygenated and deoxygenated hemoglobin are calculated from the changes in the attenuation of the measurement light. This is done by solving a linear equation based on the modified Lambert-Beer law. To solve this equation, we need to know the partial optical pathl...

journal_title：Journal of biomedical optics

authors： Umeyama S,Yamada T

更新日期：2009-05-01 00:00:00

abstract：:We demonstrate dynamic in vivo imaging using a low-cost portable pulsed laser diode (PLD)-based photoacoustic tomography system. The system takes advantage of an 803-nm PLD having high-repetition rate ∼7000  Hz combined with a fast-scanning single-element ultrasound transducer leading to a 5 s cross-sectional imaging....

journal_title：Journal of biomedical optics

authors： Upputuri PK,Pramanik M

更新日期：2017-09-01 00:00:00

abstract：:The Nikon C1 confocal laser scanning microscope is a relatively inexpensive and user-friendly instrument. We describe a straightforward method to convert the C1 for multiphoton microscopy utilizing direct coupling of a femtosecond near-infrared laser into the scan head and fiber optic transmission of emission light to...

journal_title：Journal of biomedical optics

authors： Mancuso JJ,Larson AM,Wensel TG,Saggau P

更新日期：2009-05-01 00:00:00

abstract：:We have developed a novel parallel-plate diffuse optical tomography (DOT) system for three-dimensional in vivo imaging of human breast tumor based on large optical data sets. Images of oxy-, deoxy-, and total hemoglobin concentration as well as blood oxygen saturation and tissue scattering were reconstructed. Tumor ma...

journal_title：Journal of biomedical optics

authors： Choe R,Konecky SD,Corlu A,Lee K,Durduran T,Busch DR,Pathak S,Czerniecki BJ,Tchou J,Fraker DL,Demichele A,Chance B,Arridge SR,Schweiger M,Culver JP,Schnall MD,Putt ME,Rosen MA,Yodh AG

更新日期：2009-03-01 00:00:00

abstract：:Monitoring a degranulation process in a live mast cell is a quite important issue in immunology and pharmacology. Because the size of a granule is normally much smaller than the resolution limit of an optical microscope system, there is no direct real-time live cell imaging technique for observing degranulation proces...

journal_title：Journal of biomedical optics

authors： Yang W,Lee S,Lee J,Bae Y,Kim D

更新日期：2010-07-01 00:00:00

abstract：:A need exists for the continued development of diagnostic tools and methods capable of distinguishing and characterizing slight differences in the optical properties of tissues. We present a method to estimate the scattering coefficient contribution as a function of particle size in complex mixtures of polystyrene sph...

journal_title：Journal of biomedical optics

authors： Cameron BD,Li Y,Nezhuvingal A

更新日期：2006-09-01 00:00:00

abstract：:Raman spectroscopy on single, living epithelial cells captured in a laser trap is shown to have diagnostic power over colorectal cancer. This new single-cell technology comprises three major components: primary culture processing of human tissue samples to produce single-cell suspensions, Raman detection on singly tra...

journal_title：Journal of biomedical optics

authors： Zheng F,Qin Y,Chen K

更新日期：2007-05-01 00:00:00

abstract：:We present the light scattering properties of individual human red blood cells (RBCs). We show that both the RBC static and dynamic scattering signals are altered by adenosine 5'-triphosphate (ATP)-driven membrane metabolic remodeling. To measure the light scattering signal from individual RBCs, we use diffraction pha...

journal_title：Journal of biomedical optics

authors： Park Y,Best-Popescu CA,Dasari RR,Popescu G

更新日期：2011-01-01 00:00:00

abstract：:The nEUROPt protocol is one of two new protocols developed within the European project nEUROPt to characterize the performances of time-domain systems for optical imaging of the brain. It was applied in joint measurement campaigns to compare the various instruments and to assess the impact of technical improvements. T...

journal_title：Journal of biomedical optics

authors： Wabnitz H,Jelzow A,Mazurenka M,Steinkellner O,Macdonald R,Milej D,Żołek N,Kacprzak M,Sawosz P,Maniewski R,Liebert A,Magazov S,Hebden J,Martelli F,Di Ninni P,Zaccanti G,Torricelli A,Contini D,Re R,Zucchelli L,Spine

更新日期：2014-08-01 00:00:00

abstract：:A classifier capable of ranking structural alterations of the cytoskeleton is developed. Images of cytoskeletal microtubules obtained from the epifluorescence microscopy of primary culture rat hepatocytes are analyzed. Morphological descriptors are extracted by contour and mass fractal analysis, direct methods, and sp...

journal_title：Journal of biomedical optics

authors： Crosta GF,Urani C,Fumarola L

更新日期：2006-03-01 00:00:00

abstract：:Near-infrared spectroscopy is a novel imaging technique potentially sensitive to both brain hemodynamics (slow signal) and neuronal activity (fast optical signal, FOS). The big challenge of measuring FOS noninvasively lies in the presumably low signal-to-noise ratio. Thus, detectability of the FOS has been controversi...

journal_title：Journal of biomedical optics

authors： Medvedev AV,Kainerstorfer JM,Borisov SV,Gandjbakhche AH,Vanmeter J

更新日期：2010-11-01 00:00:00

abstract：:The use of reduced nicotinamide adenine dinucleotide (NADH) fluorescence to gain metabolic information on kidneys in response to an alteration in oxygen availability has previously been experimentally demonstrated, but signal quantification has not, to date, been addressed. In this work the relative contribution to ra...

journal_title：Journal of biomedical optics

authors： Raman RN,Pivetti CD,Rubenchik AM,Matthews DL,Troppmann C,Demos SG

更新日期：2009-03-01 00:00:00

abstract：:Characterization and three-dimensional (3-D) localization of human cancerous prostate tissue embedded in normal prostate tissue were demonstrated using backscattering scanning polarization imaging and an inverse imaging reconstruction algorithm, optical tomography using independent component analysis (OPTICA). Two-dim...

journal_title：Journal of biomedical optics

authors： Pu Y,Wang W,Xu M,Eastham JA,Tang G,Alfano RR

更新日期：2012-08-01 00:00:00

abstract：:Using commercially available organic fluorophores, the current applications of Förster (fluorescence) resonance energy transfer (FRET) are limited to about 80 Å. However, many essential activities in cells are spatially and/or temporally dependent on the assembly/disassembly of transient complexes consisting of large-...

journal_title：Journal of biomedical optics

authors： Maliwal BP,Raut S,Fudala R,D'Auria S,Marzullo VM,Luini A,Gryczynski I,Gryczynski Z

更新日期：2012-01-01 00:00:00

abstract：:Shallow lesions less than 1.5-cm deep are frequently seen in breast patients when they are scanned in reflection geometry. Two boundary conditions are compared for imaging shallow lesions, and a new probe design is introduced. A partial reflection boundary condition is suitable for imaging shallow lesions less than 1....

journal_title：Journal of biomedical optics

authors： Xu C,Yuan B,Zhu Q

更新日期：2008-07-01 00:00:00

abstract：:Fast estimation of optical properties from reflectance measurements at two spatial frequencies could pave way for real-time, wide-field and quantitative mapping of vital signs of tissues. We present a machine learning-based approach for estimating optical properties in the spatial frequency domain, where a random fore...

journal_title：Journal of biomedical optics

authors： Panigrahi S,Gioux S

更新日期：2018-12-01 00:00:00

abstract：:Investigating the elasticity of ocular tissue (cornea and intraocular lens) could help the understanding and management of pathologies related to biomechanical deficiency. In previous studies, we introduced a setup based on optical coherence tomography for shear wave elastography (SWE) with high resolution and high se...

journal_title：Journal of biomedical optics

authors： Nguyen TM,Arnal B,Song S,Huang Z,Wang RK,O'Donnell M

更新日期：2015-01-01 00:00:00

abstract：:The capability of optical coherence tomography (OCT) to perform "optical biopsy" of tissues within a depth range of 1 to 2 mm with micron-scale resolution in real time makes it a promising biomedical imaging modality for dermatologic applications. Three high-speed, spectrometer-based frequency-domain OCT systems opera...

journal_title：Journal of biomedical optics

authors： Alex A,Povazay B,Hofer B,Popov S,Glittenberg C,Binder S,Drexler W

更新日期：2010-03-01 00:00:00

abstract：:Microstructures of unstained human melanoma skin tissues have been examined by multimodal nonlinear optical microscopy. The polarized shape of the individual melanoma cell can be readily recognized-a phenotype that has been identified in laboratory cultures as characteristic of proliferating melanocytes but has not be...

journal_title：Journal of biomedical optics

authors： Zhang K,Zhang W,Yang CY,Yang H

更新日期：2009-03-01 00:00:00

abstract：:We describe a wide-field optical tomography technique, which allows the measurement-guided optimization of illumination patterns for enhanced reconstruction performances. The iterative optimization of the excitation pattern aims at reducing the dynamic range in photons transmitted through biological tissue. It increas...

journal_title：Journal of biomedical optics

authors： Venugopal V,Intes X

更新日期：2013-03-01 00:00:00

abstract：:Collagen fiber orientation plays an important role in determining the structure and function of the articular cartilage. However, there is currently a lack of nondestructive means to image the fiber orientation from the cartilage surface. The purpose of this study is to investigate whether the newly developed optical ...

journal_title：Journal of biomedical optics

authors： Yao X,Wang Y,Ravanfar M,Pfeiffer FM,Duan D,Yao G

更新日期：2016-11-01 00:00:00

abstract：:Quantitative and qualitative evaluations of structure and composition are important in monitoring development of engineered vascular tissue both in vitro and in vivo. Destructive techniques are an obstacle for performing time-lapse analyses from a single sample or animal. This study demonstrates the ability of time-re...

journal_title：Journal of biomedical optics

authors： Fatakdawala H,Griffiths LG,Humphrey S,Marcu L

更新日期：2014-08-01 00:00:00

abstract：:Dynamic analyses of vibrational motion in cell membranes provide a lot of information on the complex dynamic motilities of a red blood cell (RBC). Here, we present the correlation properties of membrane fluctuation in discocyte and spherocyte RBCs by using quantitative phase microscopy (QPM). Since QPM can provide nan...

journal_title：Journal of biomedical optics

authors： Lee S,Lee JY,Park CS,Kim DY

更新日期：2011-07-01 00:00:00

abstract：:In a previous study, we investigated physical methods to reduce whole-body, diet-related autofluorescence interference in several mouse strains through changes in animal diet. Measurements of mice with an in vivo multispectral imaging system over a 21-day period allowed for the quantification of concentration changes ...

journal_title：Journal of biomedical optics

authors： Bouchard MB,MacLaurin SA,Dwyer PJ,Mansfield J,Levenson R,Krucker T

更新日期：2007-09-01 00:00:00

abstract：:Laser speckle contrast imaging is a technique used for imaging blood flow without scanning. Though several studies have attempted to combine spatial and temporal statistics of laser speckle images for reducing image noise as well as preserving acceptable spatiotemporal resolution, the statistical accuracy of these spa...

journal_title：Journal of biomedical optics

authors： Qiu J,Li P,Luo W,Wang J,Zhang H,Luo Q

更新日期：2010-01-01 00:00:00

abstract：:A reflectance volume holographic imaging (VHI) endoscope has been designed for simultaneous in vivo imaging of surface and subsurface tissue structures. Prior utilization of VHI systems has been limited to ex vivo tissue imaging. The VHI system presented in this work is designed for laparoscopic use. It consists of a ...

journal_title：Journal of biomedical optics

authors： Howlett ID,Han W,Gordon M,Rice P,Barton JK,Kostuk RK

更新日期：2017-05-01 00:00:00

abstract：:A confocal imaging and image processing scheme is introduced to visualize and evaluate the spatial distribution of spectral information in tissue. The image data are recorded using a confocal laser-scanning microscope equipped with a detection unit that provides high spectral resolution. The processing scheme is based...

journal_title：Journal of biomedical optics

authors： Maeder U,Marquardt K,Beer S,Bergmann T,Schmidts T,Heverhagen JT,Zink K,Runkel F,Fiebich M

更新日期：2012-10-01 00:00:00