Bipolar cellular morphology of malignant melanoma in unstained human melanoma skin tissue.

Abstract:

:Microstructures of unstained human melanoma skin tissues have been examined by multimodal nonlinear optical microscopy. The polarized shape of the individual melanoma cell can be readily recognized-a phenotype that has been identified in laboratory cultures as characteristic of proliferating melanocytes but has not been demonstrated in clinical instances. The results thus provide snapshots of invading melanoma cells in their native environment and suggest a practical means of connecting in vitro laboratory studies to in vivo processes.

journal_name

J Biomed Opt

authors

Zhang K,Zhang W,Yang CY,Yang H

doi

10.1117/1.3120491

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

024042

issue

2

eissn

1083-3668

issn

1560-2281

journal_volume

14

pub_type

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